Abstract
Verrucous carcinoma, a variant of squamous cell carcinoma, was first described as a distinct clinical and histopathological entity by Ackerman in 1948. In this paper, two cases of verrucous carcinoma of the oral cavity are reported. One case was treated by surgical excision, but the other rejected the treatment. The first case is free from recurrence as of today, 4 years and 4 months after surgery.Ultrastructural observations demonstrated that gap junctions and desmosomes were numerously found in the verrucous carcinoma.A well preserved intercellular junction might be rclatcd to a better prognosis of this lesion in comparison with invasive carcinomas.
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