Abstract
The one of the urgent problems in dentistry is earlier and effective treatment of premalignant diseases of the oral mucosa. High risks of malignant mucosal lesions necessitate a combination of conservative and surgical treatment. In this article we presents clinical examples of treatment of leukoplakia with extensive lesions of the oral mucosa. We performed cryodestruction for patients with liquid nitrogen (t = -1960C), with a preliminary histological examination and further observation. We estimated the duration of rehabilitation, wound healing and mucosal repair Immediately after cryotherapy, edema and hyperemia appeared. Within three days a fibrin membrane was formed, under which the process of epithelialization of the mucosa proceeded from 7 to 10 days. Clinically, there was no deformation of the mucous areas of the oral cavity, contractures.
Published Version
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