ФАРМАКОЛОГІЧНА ДІЯ ПРЕПАРАТУ «ЕКОСОРБ 25» ТА ВПЛИВ НА РІВЕНЬ НАПРУЖЕНОСТІ ІМУНІТЕТУ СВИНЕЙ, ЩО ЗНАХОДЯТЬСЯ НА ВІДГОДІВЛІ

Abstract

In the articles resulted the uses of preparation given inrelation to expediency are with adsorbent properties of «Еcosorb 25» for pigs that are on fattening. Undertakenstudies it is well–proven that introduction in the complementof ration of the indicated adsorbent from a calculation 5 kg/1the ton of forage is predetermined by an increase in the serum of blood of content of immunoproteins. Content ofimmunoproteins is in the serum of blood of pigs, that it isexposed to research to application of adsorbent was differentand was in a wide range, a mean value was 15.9 ± 3.2 gs/l immune status of investigational population is different Accordingly. Consider that such wide range of data testifiesto different activity of functioning of the immune system andconditioned by the different antigen loading each ofinvestigationalanimals. In a 21 twenty–four hours, after thebeginning of application of adsorbent of «Еcosorb 25» content of immunoproteins in the serum of blood of pigs of anexperience group is considerably less in comparing to theanimals that in composition a ration got «Ecosorb 25». Forthese pigs (control group) content of immunoproteins was at the level of a 16.6 ± 1.27g/l, but substantially differed for every animal, that testifiedtheir immune status to different. For the pigs of an experiencegroup a difference is between the least and maximal index ofcontent of immunoproteins presented 17.8% that specified onalmost identical reactivity of the immune system (reduction ofreceipt of antigens, maybe and mycotoxins from agastrointestinal tract). Got the given is conditioned by thedisplay of adsorbent action of preparation that is entered to the ration of pigs of an experience group. Positive influence of «Ecosorb 25» on functioning of the immune system atintroduction to the ration of pigs that are on fattening, theresults of research of serum of blood testify through 2 missesafter the beginning of application. Reduction to content of immunoproteins is registered in theserum of blood of pigs of control group on 15.7% comparing to the previous index (21twenty–four hours) and 19.5% animals of an experience group. For certain (Р ≥ 0,99) contentof immunoproteins increased in the serum of blood of pigs ofan experience group 17 ± 0.25 gs/of to 14.0 ± 0.76 g/l that maybe it contingently the receipt of substances with animmunodepressive action (including and micotoxins) in the organism of animals of control group. Id est, at feeding to the pigs of preparation of «Ecosorb 25» with adsorbent properties during 2th months, stipulated reduction of receiptof toxins in blood, and accordingly and reduction offunctional activity immune. It provides rapid reactivity of the immune system andsynthesis of sufficient amount of antibodies at the hit ofmicroorganisms to the organism of pigs, that in compositiona ration got an adsorbent. As for the animals of control group registered reduction to content of immunoproteins in theserum of blood, it testifies to weakening of functional activityof the immune system. The difference of content ofimmunoproteins in the serum of blood of pigs testifies to the increase of providing of better immunological defence in the organism of animals of anexperience group and reduction of him in a control group.