Комплексная диагностика острого панкреатита у собак

Abstract

This article presents typical results obtained from a general clinical blood test in dogs with signs of pancreatic pathology: leukocytosis with a shift to the left, thrombocytopenia, anemia, increased ESR. In the diagnosis of acute pancreatitis, an increase in a-amylase and lipase in the blood serum is considered important indicators. It is believed that the a-amylase activity indicator immediately indicates lesions of the pancreas, however, studies have been conducted that indicated that when the a-amylase level was normal, but the lipase level was elevated, the diagnosis of pancreatitis was confirmed. Therefore, an increase in the lipase enzyme is more specific for the diagnosis of pancreatitis. It is important to determine both enzymes to diagnose pancreatic lesions. The best diagnostic indicator of acute pancreatitis is an increase in lipase, a-amylase and creatinine, which gives up to 98 % accuracy in making a diagnosis. With pathologies of the pancreas, patients often experience disturbances in carbohydrate metabolism. As a rule, this is manifested by signs of diabetes mellitus, i.e. increase in serum glucose. The disorders are explained by damage to the cells of the islet apparatus of the pancreas. Research has shown that the canine pancreatic lipase test (SNAP®cPL) is better than other methods for diagnosing acute pancreatitis in dogs. To better test for pancreatitis in animal examinations, the SNAP®cPL Test also measures cPL concentrations using ELISA technology. Thus, the test for pancreatic lipase gave a 100 % result, which confirms its high sensitivity.