РАЗРАБОТКА КИШЕЧНОРАСТВОРИМЫХ МАТРИЧНЫХ ТАБЛЕТОК С ГУМИНОВЫМИ ПРОИЗВОДНЫМИ

Abstract

Medicines based on compounds of iron, copper and zinc occupy a certain place in the pharmaceutical market. A lack of iron in the body can contribute to the development of iron deficiency anemia, and in the case of copper and zinc, a deficiency in the immune response and inflammation caused by lipid peroxidation, which ultimately leads to various joint diseases such as arthritis. The basis of the treatment and prevention of diseases is the use of chelates of salts of iron, copper and zinc, the effectiveness of which largely depends on their stability and the degree of release of trace elements in various parts of the gastrointestinal tract. Therefore, there is a need to create new long-acting drugs with a certain solubility and sufficient bioavailability. This study is devoted to the development of the optimal composition of iron, copper and zinc humate matrix tablets for oral administration.