Редкие клинические случаи поражения глазной поверхности различной этиологии

Abstract

The article presents several rare cases from clinical practice. In particular, they concern conjunctivitis, which was the first sign of COVID 19 infection, corneotoxic corneal lesions in the form of an extensive ulcer due to the abuse of local anesthetic oxybuprocaine. Other clinical cases of ocular surface damage are associated with vaccination against a new coronavirus infection, namely with the development of adenoviral keratoconjunctivitis after LASIK refractive intervention and subsequent early (after 5 days) immunoprophylaxis with the Gam-COVID-Vac vaccine, as well as with such a rare allergic complication as toxic epidermal necrolysis or Lyell's syndrome. Finally, a clinical case is presented on the membranous, hyperergic form of epidemic keratoconjunctivitis, which requires the attention of ophthalmologists, primarily in relation to differential diagnosis with true diphtheria lesions of the conjunctiva. Keywords: rare clinical cases, ocular surface, corneotoxic lesion, corneal ulcer, COVID 19, vaccination, toxic epidermal necrolysis, adenoviral conjunctivitis, hyperergic form