Abstract
Organic-inorganic hybrid nanostructures with flower-like morphology, so called nanoflowers, have received an increasing attention due to their capability to greatly enhance the activity, stability, and durability of entrapped biomolecules, which is much better than those from the conventional immobilization strategies. These hybrid nanoflowers are simply synthesized via the incubation at room temperature but show high surface roughness and large surface-tovolume ratio, which enables high loading capacity of biomolecules without severe mass transfer limitation. Based on the advantageous features, they have been applied in the field of biotechnology such as biosensor, biofuel cell, and protein digestion. To highlight the research progress on organic-inorganic hybrid nanoflowers, this review discusses the synthetic methods, structural characteristics, and recent applications of the nanoflowers. Finally, we address the future prospects of the hybrid nanoflowers in biotechnology industry, particularly for sensing, medicine, and catalyst.
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