Abstract
We have estimated the state of target-organ damage in 95 pregnant women with different forms of hypertension. The early and potentially reversible pathophysiological and pathomorphological changes of the target organs in pregnant women with hypertension are structural and functional changes of the heart and kidneys. To assess the state of the target organs we were examined the blood vessels of the ocular fundus, the presence of left ventricular hypertrophy, the thickness of the intima-media complex and the presence of microalbuminuria. It was shown that the earliest target-organ damage in pregnant women with hypertension was left ventricular hypertrophy regardless of its form. Detection of microalbuminuria depending on gestational age may serve as an additional criterion of pre-eclampsia. With consideration of the high frequency changes in the retinal vessels, especially in preeclampsia superimposed on chronic hypertension, is required further researches to evaluate the prognostic significance of these changes. Assessment of target organs in pregnant women with hypertension can be used as a surrogate prediction point of complications and adverse pregnancy outcomes.
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