탄수화물-전해질음료 보충이 고온 환경에서의 운동 시 혈중 기관 손상 지표 및 HSP 70에 미치는 영향

Abstract

The purpose of the current research is to investigate the effects of body fluid replacement by carbohydrate-electrolyte drink on serum organ damage index and heat shock protein 70(HSP 70) during exercise in high ambient temperature. The subjects of the current research were 9 healthy male. The subjects were asked to perform treadmill running at 75%HRR for 60minutes in three different conditions controlled by the environmental chamber: 1) thermoneutral environment(ET), 2) high ambient temperature environment(EH), and 3) high ambient temperature environment and body fluid replacement by carbohydrate-electrolyte drink(EHS). Ambient temperature and relative humidity were set at 18℃ and 50%, respectively, for the theromoneutral environment, and 32℃ and 50% for the high ambient temperature environment. The identical amount of carbohydrate- electrolyte drink to the amount of body fluid loss for each subject was orally ingested in the EHS. Blood sampling were taken at pre-exercise, at immediately post-exercise, and at 60minute post-exercise for examining the levels of serum organ function enzyme and HSP 70. The serum concentration of creatine kinase(CK), lactate dehydrogenase(LDH), and HSP 70 immediately post exercise appeared to be significantly higher in EH compared to the ET(p.05). The serum concentration of aspartate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN), creatinine, phosphorus was shown to significantly increase at immediately post exercise(p.05). On the base of the results of the current study, it is suggested that exercise in high ambient temperature can induce increase concentrations of organ function enzymes(CK, LDH) and HSP 70 which may negatively influence on human organ functions. Body fluid replacements during exercise in high ambient temperature, however, can attenuate the negative consequences of thermal stress on human organ functions by preventing dehydration and reducing thermal stress.