Abstract

The aim of this paper is to provide evidence regarding the necessity and the effectiveness of early intervention for ADHD, by reviewing the most important international early intervention programs for ADHD and by presenting a relevant program implemented in Greece, based on the multi-level approach in developmental psychopathology. These programs are underpinned theoretically by the biopsychosocial epigenetic model which claims that ADHD is not just the outcome of structural and functional neurobiological deficits but results from the dynamic interplay among genetic, neurophysiological, neurochemical, and environmental factors, affecting brain structure and function early in the process of development. Early intervention focuses on those processes that take place very early in development and have a causal relationship with ADHD, with the aim of modifying the underlying neurophysiology and producing generalized long-lasting change. The efficacy of early intervention mainly lies in the fact that it takes place during a period when brain plasticity is great. Plasticity is an intrinsic property of the brain that ensures dynamic modifications at multiple levels of neural organization, allowing the brain to process, encode, and implement new knowledge. Although this neuronal development is to a great extent genetically programmed, it is widely acknowledged that environment also plays a major role through the process of epigenesis by moderating gene expression with subsequent alterations in brain structure and function and allowing even modification of certain deficient structures.

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