Introduction. Heat emission and plastic deformation during friction stir welding (FSW) cause profound changes in the microstructure and structural properties of weld joints. The grain size, crystallographic texture evolution and second-phase precipitate are the most important microstructural changes during welding of aluminum alloys, which largely influence the strength properties of weld joints. In addition to process-dependent parameters (instrument sump force, its rotation frequency, and travel rate) of the FSW process, a significant factor, determining the properties of the obtained weld joints, is also a mutual orientation of structural elements of the weld material and the direction of the instruments impact on the material during welding. In this regard, the purpose of the work is to analyze the combined influence of the direction of the initial rolling and the instrument pressure during FSW on the structure and properties of weld joints from the AA5056 aluminum alloy. Methods. Research methods are mechanical tests for statistical tension, microhardness as well as metallographic analysis of the structure of welded joints. Results and discussion. As a result, it is established that at low values of the axial force on the instrument (7 kN), defects such as the joint line and voids are observed in welded joints both rolling and transverse directions. When the load increases from 8 kN to 12 kN, defect-free weld joints with enhanced mechanical properties form. It is determined that the rolling direction of AA5056 during FSW does not influence the structure and tensile strength of the weld joints, but it influences the relative elongation and microhardness. It is shown that in the stir zone of the weld joint, obtained by FSW in the transverse direction of AA5056 flats, the relative elongation is 1.3-2 times greater, and the microhardness is by 4-10% greater than that in the stir zone of weld joints, obtained by FSW in the rolling direction of AA5056 flats.