Focusing on major earthquakes (EQs; MS ≥ 7) in Western China, this study primarily analyzes the fluctuation in Atmospheric Chemical Potential (ACP) before and after the Wenchuan, Yushu, Lushan, Jiuzhaigou, and Maduo EQs via Climatological Analysis of Seismic Precursors Identification (CAPRI). The distribution of vertical ACP revealed distinct altitude-dependent characteristics. The ACP at lower atmospheric layers (100–2000 m) exhibited a high correlation, and this correlation decreased with increasing altitude. Anomalies were detected within one month prior to each of the five EQs studied, with the majority occurring 14 to 30 days before the events, followed by a few additional anomalies. The spatial distribution of anomalies is consistent with the distribution of fault zones, with noticeable fluctuation in surrounding areas. The ACP at an altitude of 200 m gave a balance between sensitivity to seismic signals and minimal surface interference and proved to be optimal for EQ monitoring in Western China. The results offer a significant reference for remote sensing studies related to EQ monitoring and the Lithosphere–Atmosphere–Ionosphere Coupling (LAIC) model, thereby advancing our understanding of pre-seismic atmospheric variations in Western China.
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