In the crystal of the title compound, [ZnCl2(C5H5N3O)2], the molecule has m symmetry, with the ZnII cation and Cl− anions located on the mirror plane. The ZnII cation is coordinated by two Cl− anions and two pyrazine-2-carboxamide ligands in a distorted ZnCl2N2 tetrahedral geometry. The two pyrazine rings are nearly perpendicular to each other [dihedral angle = 86.61 (10)°]. Intermolecular N—H⋯O and N—H⋯N hydrogen bonds and weak C—H⋯O interactions stabilize the crystal packing.