The use of zinc oxide ointment applied locally to the rectum three times daily and at bedtime in the treatment of pinworms has been described. Eighty per cent of twenty-five children so treated were cured compared to an 89.5 per cent cure rate in nineteen children treated with syrup of piperazine. The use of zinc oxide ointment applied locally to the rectum three times daily and at bedtime in the treatment of pinworms has been described. Eighty per cent of twenty-five children so treated were cured compared to an 89.5 per cent cure rate in nineteen children treated with syrup of piperazine.