A globally aging population results in the long-term care of people with chronic illnesses, affecting the living quality of the elderly. Integrating smart technology and long-term care services will enhance and maximize healthcare quality, while planning a smart long-term care information strategy could satisfy the variety of care demands regarding hospitals, home-care institutions, and communities. The evaluation of a smart long-term care information strategy is necessary to develop smart long-term care technology. This study applies a hybrid Multi-Criteria Decision-Making (MCDM) method, which uses the Decision-Making Trial and Evaluation Laboratory (DEMATEL) integrated with the Analytic Network Process (ANP) for ranking and priority of a smart long-term care information strategy. In addition, this study considers the various resource constraints (budget, network platform cost, training time, labor cost-saving ratio, and information transmission efficiency) into the Zero-one Goal Programming (ZOGP) model to capture the optimal smart long-term care information strategy portfolios. The results of this study indicate that a hybrid MCDM decision model can provide decision-makers with the optimal service platform selection for a smart long-term care information strategy that can maximize information service benefits and allocate constrained resources most efficiently.