Background: Metabolic syndrome (MetS) is closely related to the risk of cardiovascular disease (CVD), particularly in stressful occupations. Firefighting is a hazardous profession and is associated with high metabolic risk. However, limited studies on firefighters are available. Objectives: This study aimed to determine the prevalence of MetS among firefighters in Zahedan city, Iran. Methods: This cross-sectional study was performed on 140 firefighters (age range, 16 - 55 years) employed at the fire department in Zahedan city, southeast Iran. Anthropometric characteristics and metabolic risk parameters, including blood pressure (BP), fasting blood sugar (FBS), and lipid profile were measured, and the prevalence of metabolic syndrome was assessed based on National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Results: MetS was presented in 47 (33.6%) of the firefighters. Among the metabolic risk factors, abdominal obesity (87.1%), low-high density lipoprotein (HDL-C) (62.1%), and hypertriglyceridemia (61.4%) were more prevalent. Moreover, a significant increasing trend was found with increasing age and work experience (both, P = 0.05). However, no significant differences were found for the remaining metabolic risk factors. Conclusions: The findings showed that about one-third of the firefighters had MetS. Age, abdominal obesity, and dyslipidemia were independent risk factors for MS in the firefighters. Thus, efforts should be undertaken to implement healthy lifestyle promotion programs for firefighters.