Background: Respiratory diseases are among the comorbidities associated with obesity. According to changes in their lifestyles, young people are more likely to become obese. This correlation between obesity and respiratory diseases is particularly concerning for young people, as their lifestyle choices play a significant role in their overall health. Factors such as sedentary behavior, unhealthy eating habits, and a lack of physical activity contribute to the increased likelihood of obesity in this age group. Aims and Objectives: The objective of the study was to compare the respiratory fitness levels of obese males and females to evaluate the effect of obesity on respiratory fitness in young people. Materials and Methods: In this research study, 100 young adults of age group 18–25 years from medical college were examined. Two groups were made one group consisted of 50 adults with obesity and another group of 50 controls, encompassing both males and females. We have used body mass index and waistto-hip ratio to decide obesity. Vital capacity, peak expiratory flow rate (PEFR), and respiratory rate were measured in them. Results: Comparing the obese group to the control group, a significant decrease in vital capacity (2.50 ± 0.57 vs. 2.82 ± 0.61; P = 0.01*) and PEFR (487.44 ± 94.91 vs. 586.40 ± 77.78; P ≤ 0.001**). When comparing the vital capacity and PEFR of males and females who were obese, we observed that the females had a considerably reduced vital capacity (2.35 ± 0.51 vs. 2.67 ± 0.59; P < 0.05*) and reduced PEFR (400.00 ± 69.10 vs. 487.44 ± 94.91; P < 0.001**) than obese males. Conclusion: The findings indicate that young obese people, male and female alike, have a higher likelihood of developing respiratory comorbidities in the future. Compared to obese males, obese females are more vulnerable. Therefore, by promoting physical fitness among young people, we can help reduce the risk of developing respiratory comorbidities later in life. It is crucial to prioritize their health and provide them with the necessary support and resources to maintain a healthy lifestyle.