La-MOF has an excellent chance of eliminating food and industrial coloring pollutants from water because it is a typical metal-organic framework material. Nevertheless, the challenging liquid recovery has restricted the use of this powdered adsorbent. In order to solve this shortcoming, we created composite beads (La-MOF@CA aerogel composite sponge) by solidifying sodium alginate and La-MOF together. A common technique to boost an adsorbent material's adsorption capability is to modify its composition; this is especially true for adsorbents composed of metal organic framework. The effects of La-MOF@CA aerogel composite sponge on the adsorption and elimination of tartrazine (TZ) were examined in this study. Following thorough characterization, the following tests were performed: X-ray diffraction (XRD), energy-dispersive X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and Brunauer-Emmett-Teller surface area (BET). The La-MOF@CA aerogel composite sponge has a significant high surface area of 1244.68 m2/g and this surface area was decrease after adsorption of TZ to be 768.98 m2/g. the greatest adsorption capacity (qmax) of for TZ, 710.75 mg/g. Examine how the adsorption process is impacted by factors like temperature, adsorbent dosage, pH, and TZ concentration. The pHZPC was 5.18 and optimum pH for adsorption and removal of TZ was 4. The adsorption process was fitted to the pseudo-second-order equation kinetically, and to the Langmuir equation isothermally. As the adsorption energy Ea was 22.76 kJ/mol indicated that the adsorption process was chemisorption. The adsorption process was thought to be endothermic and spontaneous based on adsorption thermodynamics. The temperature increased in tandem with the amounts of materials absorbed. With good efficiency, no change in chemical composition, and similar XRD and XPS data before and after reuse, the La-MOF@CA aerogel composite sponge was reused five times. Examine the interaction mechanism between the heavy TZ and the La-MOF@CA aerogel composite sponge. Box Behnken-design was used to maximize the adsorption results (BBD).