Years Of Age Group Research Articles

Assessment of Screen Time with its Effect on Health among Secondary School Students

Background: Secondary school students are more and more immersed in a world dominated by screens in the modern digital era. Screens, ranging from laptops to tablets, televisions to smartphones, have embedded themselves into daily life and significantly impact how youngsters communicate, learn, and pass the time. Objective: The study's objective was to find out the assessment of screen time and its effect on health among rural secondary school students in Bangladesh. Methods: This cross-sectional descriptive type of study was carried out in Govt. Jalma Chakrakhali Secondary School in Batiaghata Upazilla under Khulna district. A total of 460 students were selected using a convenient sampling technique from a selected school in Khulna district. Face-to-face interviews with a semi-structured questionnaire were used to collect data. Data were analyzed following the study's objectives. Before data collection, informed consent was taken, and ethical concerns were addressed at different stages of the study. Results: Among 460 respondents, a large number 52% (241) were between 14-16 years of age group. Only 38% had a personal mobile phone, while where a maximum (72%) used their parents' phones. Male students (76%) had a greater tendency to operate mobile phones in comparison to females (64%). Among the parents, most of them (82%) had a smartphone. Most of the respondents [395 (86%)] had a TV at their house and 304 (66%) watched TV regularly. Almost half of the respondents [223(48%)] suffered from various health issues, where headaches and blurring of vision were the main features. Conclusion: This study painted a clear picture of the effect of screen time on Bangladeshi rural school-going youngsters, and it may be able to assist the relevant authorities in developing policies and formulating plans to address the issue. Mediscope 2024;11(2): 82-86

Prescription Testosterone is Associated with an Increased Risk of Anterior Cruciate Ligament Injury

To characterize the relationship between testosterone replacement therapy (TRT) and anterior cruciate ligament (ACL) injuries. A retrospective cohort study using a large insurance database was conducted. Patients who were prescribed TRT for at least 3 months were matched with controls who were not prescribed TRT. Rates of ACL tears were compared between the cohorts. Multiple subgroups were created based on age (<25 years, 25-35, 36-45, 46-55, 56-65, and 65+). Multivariable logistic regressions were performed to determine the association of TRT with ACL tears while accounting for demographic variables and comorbidities. After matching, there were 160,839 patients in both the TRT cohort and control cohort. The incidence of ACL injuries was 17.8 per 10,000 person-years (95% CI: 16.4-19.2) for patients who were prescribed TRT and 4.9 per 10,000 person-years (95% CI: 4.1-5.7) for controls (p<0.001). Within 2 years of filling a testosterone prescription for at least 3 months, 572 (0.35%) patients experienced an ACL injury compared to only 157 (0.10%) controls during the same follow-up period (OR: 2.77; 95% CI: 2.26-3.42, p<0.001). When stratified by age, all groups except the <25 years of age group demonstrated significantly higher rate of ACL tears (OR 3.91-12.3, p<0.001-0.009). When separated by sex, males on TRT were 3.13 (95% CI: 2.50-3.93, p<0.001) times more likely while females on TRT were 1.94 (95% CI: 1.13-3.41, p=0.018) times more likely to experience an ACL injury compared to controls. This study found that patients prescribed at least three months of TRT had a significantly higher incidence of ACL injuries compared to controls within a two-year follow-up period. Level III, retrospective comparative study.

Diffusion Tensor Imaging of the Auditory Pathway in Prelingual Deaf Children in Comparison to Normal Hearing Children in the 1 to 7 Years of Age Group

Abstract Objective This article aims to determine the microstructural alterations in the auditory pathway in prelingual deaf children using diffusion tensor imaging (DTI)-derived parameters—fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and secondarily to evaluate these changes in rubella and cytomegalovirus (CMV) positive cases. Method A consecutive series of consenting deaf and normal children between 1 and 7 years of age, forming the case and control groups, respectively, underwent DTI, audiological tests, and testing for rubella, CMV, and toxoplasma infections. FA and ADC were measured at four locations bilaterally: lateral lemniscus (LL), inferior colliculus, medial geniculate body, and auditory cortex (AC). Result The mean ADC values were higher and the mean FA values were lower in cases (19 males, 21 females, mean age 2.65 years) than the controls (21 males, 19 females, mean age 4.63 years) at all eight sites. Sixteen (40%), 17 (42.5%), and 7 (17.5%) cases had severe, severe to profound, and profound hearing loss, respectively, the FA and ADC values being significantly different for LL. For rubella and CMV immunoglobulin G, 20/40and 17/40 cases were positive, respectively, 11 for both, and none for toxoplasma. Significant decrease in FA was seen at LL and AC in rubella/CMV positive cases. Conclusion Microstructural changes are seen throughout the auditory pathway in prelingual deaf children, especially with rubella and/or CMV positive status. Further studies may pave the path to segregate out patient groups potentially more responsive to cochlear implant.

Quality of life of covid-19 patients attending selected post-covid units

Background: Disease process and its outcome can create impacts on human life; it also impairs quality of life (QoL). During the COVID-19 pandemic situation, a devastating impairment of quality of human life has been occurred over the world. This study aimed to state the quality of life of COVID-19 patients attending post-COVID units of Dhaka Medical College Hospital and Bangabandhu Sheikh Mujib Medical University, Dhaka. Methods: A cross-sectional study was conducted among 90 COVID-19 Patients (post-COVID period) in post COVID unit of Dhaka Medical College Hospital and Bangabandhu Sheikh Mujib Medical University by pretested structured questionnaire, from July 2021 to December 2021, using a convenient sampling method. Data were collected through face-to-face interviews. Results: The majority of the respondents (46.7%) were within the 30 to 39 years of age group. In this study about 73.3% of respondents lead poor quality of life after recovery from COVID-19. The findings revealed that, Post COVID depression history of the respondents was associated with the quality of life of the respondents after recovery from COVID-19 (p=0.001). The findings also revealed that the type family of the respondents was associated with the quality of life of the respondents after recovery from COVID-19 (p=0.001). Those who were not admitted into hospital during COVID-19 period maintain good quality of life after recovery from COVID-19 than those who were admitted on hospital during COVID-19 period (p=0.006). Inferential statistics were done at a 95% confidence interval and 5% level of significance. Conclusions: This study described state of quality of life of COVID-19 patients attending on post-COVID units. It was found that near about three fourth of the respondents seemed that their quality of life became poor after recovery from COVID-19. JOPSOM 2023; 42(1):49-53

Examining Disparities in Regional Anesthesia Utilization, Opioid Prescriptions, and Pain Scores Among Patients Who Received Primary or Revision Total Knee Arthroplasty at a Veterans Affairs Medical Center: A Retrospective Cohort Study.

Total knee arthroplasty (TKA) is one of the most performed surgical operations in the United States. Managing postoperative pain after TKA is of vital importance, as it is positively associated with outcome measures related to recovery of function and quality of life. Two commonly used methods to control postoperative pain are regional anesthesia (RA), consisting of a single or a combination of peripheral nerve and epidural blocks, and pain medication, such as opioids. Our retrospective analysis sought to better understand whether revision versus primary TKA impacted previously discovered disparities in perioperative pain management and use of RA at the Atlanta Veterans Affairs Health Care System (AVAHCS). Before data collection, we hypothesized that revision TKA would have a higher proportion of Black and older patients and that revision TKA patients would have lower postoperative pain scores. This was a retrospective analysis of AVAHCS patients who underwent elective unilateral primary or revision TKA surgery between 2014 and 2020. After application of our exclusion criteria, data from 562 patients were analyzed. Data collected included demographics information, type of RA used, and pain scores. Statistical analyses included chi-square test, t-tests, multiple logistic regression, and multiple linear regression, as appropriate to the outcomes of interest. Revision TKA patients were more likely to be Black (P = .018) and younger (P = .023 for <50 years of age group, P = .006 for 50 to 64 years of age compared to the >65 years group). Black patients, compared to White patients, had significantly higher pain scores at baseline (P = .0086) and at 24 hours postsurgery (P = .0037). Older patients (≥50 years old) had significantly higher baseline pain scores (P = .021 for the 50 to 64 years group, P < .01 for the >65 years group) and significantly lower first postanesthesia care unit pain scores (P < .05). Black race (P < .01) and age > 65 years (P < .01) were associated with a significant decrease in total oral morphine equivalents (OME) prescribed at discharge. None of the predictor variables-race, age, type of surgery (primary versus revision), baseline, and first postanesthesia care unit pain scores-were significantly associated with the use of RA in our cohort. Sociodemographic disparities in pain management have been reported in all healthcare systems, including the VAHCS. This moderately sized retrospective study, conducted at a single veterans affairs site, yielded several noteworthy findings. One finding of particular interest was that, despite Black patients reporting higher baseline and 24-hour postoperative pain scores, they were prescribed fewer opioids at discharge. Our results highlight the presence of clinically significant disparities in perioperative TKA pain management, emphasizing the need for continuous investigation and focused mitigation efforts among Veterans.

Pregnancy-induced Hypertension: What Are the Associated Factors in Rural Areas? A Study from Rural Dehradun, Uttarakhand

Abstract Background: Pregnancy-induced hypertension (PIH) is a major significant cause of adverse pregnancy outcomes – mortality and morbidities in both mother and foetus. Aims: The present study aims to determine the prevalence of PIH and its associated factors among pregnant women attending antenatal care in rural field areas of a tertiary care hospital in Uttarakhand. Patients and Methods: A cross-sectional study was conducted on pregnant women-seeking antenatal services from January 2020 to October 2020 at three sub-centres (Raiwala, Pratit Nagar and Haripur Kala) of the Primary Health Centre (Raiwala) after giving informed consent. A sample size of 113 was calculated and included in our study. A pre-tested structured schedule was used to interview the study participants after a pilot test. Blood pressure was determined using an average of three measurements, and some clinical and laboratory findings were reviewed from medical records; these were mainly the mother-child protection card. Data were presented as frequency, percentage frequencies and the results are presented with the table. Fisher’s exact statistics were calculated for the association with pregnancy-induced hypertension, and logistic regression was performed to identify independent predictors. P &lt;0.05% was considered statistically significant. Results: The prevalence of PIH among total study participants in Dehradun District, Uttarakhand, was 6.2% (95% confidence interval [CI], 1.8%–10.6%). The majority of respondents were noted in ≤ 30 years of age group (91.15%), followed by &gt; 30 years of age group (8.84%). In univariate regression, factors such as age, pre-term birth, abortion, pedal oedema, blurred vision, proteinuria, present history of gestational diabetes mellitus, present history of diabetes, present history of other morbidities, past history of diabetes, past history of other morbidities, i.e. surgeries, otitis media, obesity and thyroid, family history of hypertension and family history of diabetes were associated with pregnancy-induced hypertension. In multivariate logistic regression, maternal age (adjusted odds ratio AOR = 18.29, 95 CI% =2.3–141.4, P = 0.005*), pre-term birth (AOR = 61.7, 95% CI = 3.5–1071.3, P = 0.005*), (proteinuria AOR = 8, CI = 0.80–79.6, P = 0.006*), gestational diabetes (AOR = 19.9, CI = 2.9–133.06, P = 0.002*), history of other morbidities (AOR = 13.4, 95% CI; 1.7–106.5, P = 0.014*) and family history of diabetes (AOR; 8.7, 95% CI = 1.7–43.3, P = 0.008*) were found as the predictor factors for developing PIH. Conclusions: Early detection and treatment of pregnancy-induced hypertension and risk factors in pregnant women by healthcare professionals and policy-makers at the community level should be strengthened.

Influence of Health-Seeking Behavior on Treatment Initiation of Cancer Patients at a Tertiary Care Hospital in Varanasi

Abstract Background: Cancer is one of the leading causes of death worldwide, and in order to prevent it, it is vital to understand cancer patients’ health-seeking behavior that contributes to patient delays in receiving cancer treatment globally; however, no similar studies have been conducted in India. Therefore, this study made an effort to know health-seeking behavior among delayed cancer patients receiving treatment at a tertiary care hospital, Varanasi. Methods: A cross-sectional study was conducted at the Department of Surgical Oncology OPD, Sir Sunder Lal Hospital, IMS, BHU, Varanasi. Randomly selected 440 registered patients were interviewed with the help of semi-structured questionnaire. Binary logistic regression analysis and 2-test were used in this study. Results: Out of total 440 patients included in this study, 207 (47.05%) were males and 233 (52.95%) were females. The majority (59.32%) of patients were more than 45 years of age group. Most (80%) of the patients had delay in cancer treatment of more than 60 days from onset of symptoms. Only 29.55% of patients were aware of any symptoms of Cancer. Those patients who were doing self-medication (P=0.03) and did not attend any cancer screening program (P=0.04) showed a statistically significant association with delayed initiation of treatment. Patients referred from another centre (P = 0.03) also show a significant association with delayed treatment initiation. Cancer patients who visited the screening program (AOR= 0.22, P=0.003) were significantly associated with a lower likelihood of delayed treatment initiation. Conclusion: The study showed that 80% of patients were delayed in seeking treatment for Cancer and highly influenced by low awareness, self-medication and visiting multiple health centres for diagnosis and treatment. Therefore, there is a strong need to address the reasons for the delay in seeking treatment.

Differences in Cervical Spine Fractures in Patients Younger or Older Than 65 Years of Age: Implications for the Canadian C-Spine Rule.

There has been a distinction made in the 2001 Canadian C-Spine Rule regarding patients 65 and older and younger than 65 years of age as far as indications for cervical spine CT scanning. We sought to determine if there are differences in the symptoms, mechanisms of injury, fracture locations, and types that are still relevant in 2024. The institutional review board approved this retrospective study of cervical spine CT emergency department results from 2 hospitals in our health system after reviewing 5 years of data in patients experiencing trauma. In addition to the primary variable of age (younger than 65 years and 65 years and older), we looked at injury mechanism, fracture types, sites, symptoms, and operative or medical treatments. Because the demographics of our home site is different from most towns in the United States, we provide race/ethnicity data. Of 21,986 cervical spine CTs, 190/9455 (2.0%) participants 65 years of age and older and 199/12,531 (1.6%) participants younger than 65 years of age had fractures (total, 389/21,986, 1.8%). There were more cases of falls from standing (106, 55.8%) and falls from a height (46, 4.2%) in those 65 years and older and this mechanism was associated with a higher risk of C1 and C2 fractures (52, 27.4%; and 78, 41.1%, respectively). Among the C1 fractures, anterior and posterior arch fractures predominated (37, 19.5%). For C2 fractures, types 2 and 3 odontoid fractures (39, 20.5%; and 12, 6.3%) were more common in the older cohort. Motor vehicle collisions were more common in the younger cohort (89, 44.7%), and they were associated with more C5-C7 fractures (47, 23.6%; 60, 30.2%; and 66, 33.2%, respectively) including the facets (49, 24.6%), spinous processes (31, 15.6%), and transverse processes (52, 26.1%). Overall, the rates of instability, surgical intervention, and asymptomatic fractures were similar in the 2 age groups. Cervical spine fractures appear in about 1.8% of the CT scans performed in a busy emergency department environment. Fractures in the elderly occur more commonly due to falls, are located at C1 and C2, and may involve ligamentous injuries. Younger patients incur trauma more commonly due to motor vehicle collisions, and they are more likely to affect the posterior elements, especially C5-C7. The differences in trends for fractures in the 65 years of age and older and younger than 65 years of age groups have persisted since the Canadian C-Spine Rule 1996-1998 data were collected.

The Prevalence Pediatric Patients Attending in A Tertiary care Hospital in Dhaka, Bangladesh

Introduction The incidence of skin conditions in young people typically varies between nations and within a single nation’s regions based on social, economic, racial, and environmental factors. A significant public health issue is the morbidity that skin diseases cause in children. There is a dearth of research on this pediatric issue in our nation, which is either centered on a condition, a community, or a particular population group. Objective To evaluate the dermatological complaints of the pediatric patients attending a dermatology outpatient department in a tertiary care hospital. Materials And Methods We retrospectively analyzed a total of 2472 pediatric patients who were in age range 0-18 years and came to the OPD of dermatology &amp; venereology department of Ibn Sina Medical College Hospital, Dhaka, Bangladesh, over a period of 1½ year from January, 2020 to June, 2021. Data were collected on special proforma and analyzed with appropriate method. Results Among 2472 patients 1157 (46.8%) were male and 1315 (53.2%) were female and most of the patients belonged to the age group 12-18 year (52.6%). Male female ratio was 0.88:1. All diseases were broadly classified into noninfectious (71.2%) and infectious dermatoses (28.8%). Dermatitis (38.9%), infections (28.8%) and acne (14.44%) came out to be the top most common cause for OPD attendances. For the specific skin diseases, 20.1% were atopic dermatitis, 14.44% were acne, and 11.8 % were fungal infections. Atopic dermatitis was the most common condition below 12 years of age. In 12-18 years of age group, the most common condition was acne; females were more affected than males. Among the viral infections, wart was the most common (22.1%). Conclusion Atopic dermatitis was found to be the most common noninfectious disease and fungal infection was the most common infectious disease in all age groups and genders. Bangladesh Journal of Medical Science Vol. 23 No. 04 October’24 Page : 1054-1059

Mobility challenges for women: A case study of bus rapid transit Peshawar

In Pakistan, women face significant barriers to urban mobility. This is due to limited access to safe, affordable, and sustainable public transportation, exacerbated by socio-cultural norms and experiences of harassment. Addressing these challenges is crucial for promoting gender equality and unlocking women's potential for growth. This research inspects women's mobility experiences and challenges and proposes potential improvements for bus rapid transit (BRT) Peshawar. Interviews were conducted for data collection, and statistical tools and methods were employed to analyze the results. The most common modes of travel to and from the BRT stations were walk (39%&45%) followed by Taxi/Rickshaw (32%each) and car/bike(15%&9%), respectively. Most users accessed the BRT system within a 3km radius (55%) and typically traveled during the daytime (56% from 6-10 am and 51%from 2-6 pm). The main challenges identified, mainly for the younger users, were harassment faced at stations (66%for 18-30 years and 52%for 31-45 years of age groups, respectively) while on the buses with 54%for <18 years and 56%for 18-30 years of age groups, respectively, with a visual type of harassment in major. The study highlights women's unique mobility challenges with Peshawar BRT. Addressing these issues can boost their education and economic prospects, as a major study sample was comprised of lower-income employees (80% having an income less than 40,000PKR*) and middle-aged students (48%). The findings provide valuable insights for BRT Peshawar and future BRT projects in developing countries. Despite separate seats, challenges persist during peak hours due to the absence of partitions between male and female sections within buses and other BRT amenities.

Comparative Study of Pancreatic Head and Body Size in Diabetic and Nondiabetic Individuals Age Group &gt;65 Years by USG

Abstract Background and Objectives: Diabetes mellitus is the collective term for disorders affecting glucose homeostasis. The pancreas is situated in the retroperitoneum within the anterior pararenal fascial space and positioned anteriorly to the aorta and inferior vena cava. Specifically, the pancreas is commonly located just below the origin of the superior mesenteric artery. Ultrasound imaging serves as a valuable tool for acquiring detailed information about the pancreas, encompassing factors such as pancreatic size, echotexture, ductal anatomy, and the surrounding structures. This imaging modality not only facilitates diagnostic evaluations but also allows for interventional procedures, all accomplished efficiently within a brief time frame and at a minimal cost. Subjects and Methods: One hundred and fifty healthy adults as controls and 150 diabetic patients of the same age group &gt;65 years of age group were evaluated by ultrasound sonography. Results: The mean pancreatic head and body is 2.01 ± 0.38 cm and 1.26 ± 0.18 cm, respectively, in diabetic participants, whereas in controls, it is 2.40 ± 0.13 cm and 1.59 ± 0.17 cm. This showed a significant decrease in pancreatic head and body size in diabetic individuals. Interpretation and Conclusions: Diabetic individuals exhibit smaller pancreatic head and body compared to normal controls.

Endoscopic Tympanoplasty in Chronic Otitis Media with Inactive Mucosal Disease

&amp;lt;i&amp;gt;Background:&amp;lt;/i&amp;gt; Chronic otitis media (COM) is a condition usually seen in patients attending the ENT department. Chronic inactive mucosal disease (CIMD) is characterized by tympanic membrane (TM) perforation with hearing loss. Endoscopic tympanoplasty (ET) is a surgical method to repair TM perforation with minimal invasion. &amp;lt;i&amp;gt;Objective:&amp;lt;/i&amp;gt; The present analysis was done to find out the outcome of ET surgeries in CIMD. &amp;lt;i&amp;gt;Methods:&amp;lt;/i&amp;gt; Retrospective data analysis was done in 30 patients underwent ET with endoscopic under-lay technique at Al-Ameen medical college, Vijapur, India. &amp;lt;i&amp;gt;Results:&amp;lt;/i&amp;gt; Average age of patients was 34.17±9.52 years. Majority (40%) patients were from 18-30 years of age group. There were 12 (40%) males and 18 (60%) females. Right-side and left-side CIMD was equally distributed in 30 patients. Sixteen (53.3%) and 14 (46.7%) patients were having right and left TM perforation, respectively. TM perforation size was small, medium and large in 43.3%, 30% and 26.7% of patients, respectively. Twenty-eight (93.3%) patients had temporalis fascia and 2 (6.7%) patients had tragal cartilage as graft material. Two (6.7%) patients had graft rejection without improvement in hearing. No patient had complication or any miscellaneous issues. Eighteen (60.0%), 11 (36.7%) and 1 (3.3%) pre-operative patient with pure-tone average (PTA) had mild, moderate, and severe conductive hearing loss (CHL), respectively. All patients with PTA were improved after surgery. &amp;lt;i&amp;gt;Conclusion: &amp;lt;/i&amp;gt;ET is an effective, minimally invasive, and less painful surgical technique for repair of central TM perforations in CIMD.

Improving the Cardamom Marketing: Assessing the Marketing Efficiency of Cardamom in Theni District, Tamil Nadu

Introduction: The cardamom is the oldest spices and belongs to Zingiberaceae family. It is cultivated in the thick shady, rainy forests of the Western Ghats of the South India. The major growing states are Kerala, Karnataka and Tamil Nadu in reference to green cardamom (Small) and its botanical name Elettaria cardamomum. The part of Theni district is constituted by thick vegetations of hills of Western Ghats and Cumbum Valley at Bodi and Uthamapalayam taluk. In these areas, the farmers are cultivating the Cardamom. This study aims to find out the socio-economic characters, marketing behavior, assess the marketing efficiency of different supply channels and ranking the major problems faced by farmers to market their agricultural product. Methodology: The author used both primary and secondary data. The maximum area covered by cardamom was used as criteria for selecting the blocks. Purposive random sampling method was used to select the villages and the data was collected from the 60 farmers and other stakeholders using well-structured questionnaire. The descriptive statistics and percentage analysis were used for interpreting the results. For marketing analysis, marketing costs, marketing margin and price spread were estimated. For marketing efficiency, Acharya’s method (2003) was used. Results: The 34 respondents with 56.67 percent were found to be 21-35 years of age group. It was found that 7 respondents only with 11.67 percent and 26 respondents with 43.33 percent were found to be illiterate and the annual turnover of 1-5 lakh respectively. Using Acharya’s method (2003), the marketing efficiency of the channel I, II, III were 5.92, 9.97, 7.27 respectively. The price spread in the marketing channel I, II, and III are Rs. 295.94 per Kg, Rs. 163.54 per Kg and 229.48 per Kg respectively. It was shown that channel II is efficient due to high efficiency value and less price spread. Producer in the marketing channel II had highest share (90.88) in consumer rupee. The result showed that the Lack of timely adequate funds were major problem faced by the cardamom farmers with garret mean score of 65.23. The financial problems were common in the respondents. Conclusion: Marketing channel II was efficient because the spice auction center plays a vital role in protecting the farmer as well as consumer from the malpractices and exploitation of Intermediaries and to provide the transparency in trading operations of cardamom. The government may increase the financial assistance or technical support program to support the cardamom growers of the Tamil Nadu. The board should educate the farmers to grade or sort the cardamom before entering the e-Auction center to get better price for better quality of the commodity and to expand the pilot project of separate e-auctions for lab tested cardamom for artificial colours and pesticidal residues to potential markets of Tamil Nadu.

Runx2 gene single nucleotide polymorphism in Class II and Class III malocclusions

To assess the prevalence of RUNX2 gene polymorphism in skeletal class II and class III malocclusions. : Unstimulated salivary samples of 36 patients (18- 30 years of age group), comprising 18 with skeletal class II and 18 with skeletal class III were collected from a tertiary care hospital in Mangalore. Salivary DNA samples were collected and analyzed using Sanger sequencing. Digital tracing was performed on lateral cephalometric radiographs by using AutoCAD software for digitization to assess the anterio-posterior and vertical relationship of the maxillary and mandibular arch.When polymorphism of 36 samples comprised of 18 Class II and 18 Class III were assessed, 83.3% Class III malocclusion and 5.6% Class II showed RUNX2 gene polymorphism in the population. Chi Square test which indicated that the results are statistically significant in Class III malocclusion for RUNX2 single nucleotide polymorphism (p&amp;#60;0.001). RUNX2 gene polymorphism was statistically significant in skeletal Class III malocclusion when compared to skeletal Class II malocclusion. This is a preliminary study done on a smaller sample, we need a larger sample size to confirm our findings.

Revision arthrodesis in a failed knee arthrodesis for a giant cell tumor excision of distal femur: a case report

Giant cell tumor is a benign tumor with locally aggressive behaviour. It is common in 20–40 years of age group. Common location of the tumor includes distal end of femur, proximal end of tibia. It is slightly more common in females than males. We present a case of forty-four years-old lady with a persistent swelling over her left knee and was diagnosed with a distal femur giant cell tumor. After a wide excision, dual free fibula grafting and arthrodesis of the knee with a long nail was performed. However, she experienced pain and progressive deformity three years after surgery. X-rays revealed the failure of union of the free fibula graft to the residual femur and the breakage of the nail at that site. A revision arthrodesis was performed with removal of implant and stabilizing the non-united ends with dual plating with bone grafting from lateral tibial condyle and bone graft substitutes. She was discharged with left side non weight bearing mobilization with walker support and was started on full weight-bearing mobilization after one year with satisfactory union on X-rays.

Changeable factors for diabetes mellitus type II patients and compare it with healthy control

A study has been analysed “Changeable factors for diabetes mellitus type II patients and compare it with healthy control.” A random sample total 150 well-informed, informed consented subjects of either male and female 35-70 years of age group has been selected from Bihar. 100 patients suffering from diabetes mellitus type II were placed in group 1 (serving as cases) and fifty (50) apparently healthy individuals with matched age were place in group 2 (serving as a healthy control). The number of the disease population is believed to be approx. 70-90 per% of apparently healthy Indians have under vitamin D level across all the regions and age groups. In the present, diabetic cases had 19.09±5.34 ng/ml of serum vitamin D level. Healthy control subjects had 26.55±3.61 ng/ml of serum. The results been showed that 53% male and 47% female participants among cases. 40% male and 60% female participants among healthy control. Diabetes mellitus of patients, 17 cases were under good control, 28 were under fair control and 55 were under poor control. Diabetic cases had 19.09±5.34 ng/ml of serum vitamin D level. Healthy control subjects had 26.55±3.61 ng/ml of serum vitamin D.

Correlation of Hypothyroidism with Age and Comorbidities Among Women: A Cross-Sectional Study

Background Hypothyroidism, an endocrine disorder caused by thyroid dysfunction found to be more prevalent globally in females than in males. Young females are more prone to subclinical hypothyroidism (SCH). The study aimed to estimate the different types of hypothyroidism based on the clinical profile of thyroid hormone and to detect various comorbidities in correlation with age in women. In female patients with hypothyroidism, there is a significant association between age groups and the type of hypothyroidism (subclinical, clinical, overt), with younger age groups showing a higher prevalence of SCH. Additionally, comorbidities, such as polycystic ovarian disorder (PCOD), are more prevalent in hypothyroidism patients, particularly in those with SCH. Materials and Methods A prospective cross-sectional study executed in a tertiary care hospital for one year with an inclusion of female hypothyroid patients above 18 years of age. An informed written consent form was received from each patient with clarification of the protocol. Results A total of 44.6% women were in the 18–28 years of age group (young females) and 42.8% of women with SCH. PCOD (38.2%) was a predominant comorbid condition among hypothyroidism women. In the age group of 18–28 years, there were significantly more patients 114 (81.4%) with SCH ( p &lt; 0.01) than those with clinical 22 (18.4%) and overt hypothyroidism 10 (14.7%). The hypothyroidism of women with PCOD 95 (67.8%) was significantly ( p &lt; 0.01) more in subclinical than clinical 28 (23.5%) and overt hypothyroidism 2 (2.9%). Conclusion Thyroid dysfunction is uncertain in females, bulges to complications of maternal and fetal outcomes, and is associated with other comorbidities, leading to an increase in the mortality rate. Hypothyroidism is a growing burden for other comorbidities. Pharmaceutical care by healthcare professionals is to be adopted with prompt diagnostic and screening techniques.

Correlation of optic nerve on magnetic resonance imaging with visual acuity in children with cerebral visual impairment

Abstract: AIM: The aim of the study was to correlate the optic nerve dimensions at various locations on magnetic resonance imaging (MRI) with the visual acuity of children with cerebral visual impairment (CVI). MATERIALS AND METHODS: A 1-year cross-sectional study was conducted in a tertiary care hospital involving 60 children aged 1 to 12 years diagnosed with CVI but without ocular pathologies. Visual acuity was evaluated using teller acuity cards (TACs). MRI of the brain and orbit was performed using three-dimensional high-resolution, volumetric heavily T2-weighted sequences to screen for brain pathologies and measure optic nerve dimensions at two locations. The correlation between visual acuity and optic nerve dimensions was analyzed. The Chi-square test was employed to assess significance using SPSS software. RESULTS: In our study, 64% (n = 38) of the participants were children under 3 years of age. The severity and characteristics of CVI influenced visual functioning at different ages. As children with CVI grew older and moved from Phase I to Phase III, the proportion with very low visual acuity significantly decreased from 85.2% in Phase I to 22.2% in Phase III and from 63.2% in the &lt;3-year age group to 18.2% in more than 5-year age group. No direct correlation was found between optic nerve dimensions and visual acuity but optic disc changes such as optic disc pallor significantly correlated with low visual acuity. CONCLUSION: Our findings suggest that there may not be a direct correlation between optic nerve dimensions and visual acuity in children with CVI. However, optic disc changes do correlate with visual acuity, but optic disc changes alone are not a criterion for assessing visual function. Additionally, our study highlights the significance of a combined assessment by a neuro- ophthalmologist and neuro-pedaitrician in children with CVI.

Neck Circumference as A Screening Tool for Childhood Obesity: A Cross-Sectional Study

Introduction: Obesity is found to be one of the most common modifiable risk factor for lifestyle diseases, its screening has become crucial to identify it at an early stage. This study aims to find whether neck circumference is a reliable indicator to measure childhood obesity. Objectives: To analyse neck circumference as a marker of abdominal obesity in children. Methodology: A cross sectional study was conducted among 220 children between 6-11 years of age group by visiting their school. Data was analysed using MS Excel and SPSS (version 20.0). Results: 220 students were included in the study. Age, waist circumference, hip circumference and BMI are positively correlated with Neck Circumference. Conclusion: Neck circumference is a reliable tool to measure childhood obesity.

Epidemiological and Clinico-therapeutic Studies on Dermatophytosis in Cattle at Parbhani

Background: To investigate prevalence, risk factors, diagnosis and alternative treatment regimens of dermatophytosis in cattle in and around Parbhani. Methods: The overall period of prevalence study was from January, 2022 to December, 2022 in and around Parbhani. The presumptive diagnosis was done by SDA culture media and treatment was given to 18 selected positive cattle which was equally categorized into three group viz; Clove oil, Cow urine distillate and whitfield ointment/control group. Result: The overall prevalence recorded was 17.2 per cent. The most affected cattle were 4 to 8 years of age group, non-descript breed and male cattle. Dermatophytosis in adult cattle is typically manifested as a circumscribed, crusty, whitish grey lesion with focal alopecia, whereas in calf asbestos, crusty lesion was observed. The hump, neck and back were the major sites of occurrence for dermatophytosis. On cultural examination, Trichophyton verrucosumwas mostly isolated. On haematological investigation granulocytosis, monocytosis and lymphopenia were observed in affected cattle. The recovery period for Clove oil was 7 days, Cow urine distillate showed recovery in days and cattle treated with whitfield ointment recovered in 19 days.