Yashada Bhasma Research Articles

Exploring the Benefits of Yashada Bhasma (Zinc Oxide) in Sunscreen Formulations: Bridging Classical Wisdom with Scientific Validation

The utilization of minerals in cosmetic formulations has been a longstanding tradition, with Yashada Bhasma (zinc oxide) emerging as a prominent ingredient in modern sunscreen formulations due to its remarkable properties. This article provides a comprehensive examination of Yashada Bhasma historical significance, chemical composition, and therapeutic attributes as described in classical literature. The scientific analysis validates its efficacy as a physical barrier against UVA and UVB radiation, highlighting its photostability and compatibility with sensitive skin. Structural and chemical characterization techniques illuminate its nano-scale transformation during the purification process, enhancing its effectiveness. Comparative analyses with other sunscreen ingredients emphasize its superiority in terms of UV protection spectrum, skin compatibility, and regulatory approval. A market survey reveals the widespread incorporation of Yashada Bhasma into various Ayurvedic and herbal cosmetic products, reflecting its acceptance and popularity among consumers. Overall, this article bridges the gap between Classical wisdom and scientific validation, showcasing Yashada Bhasma as a versatile and effective component in sunscreen formulations, poised to meet the evolving needs of skincare and sun protection in contemporary times.

Application of Ayurvedic Bhasma for the Treatment of Cancer

ABSTRACT The application of Ayurvedic Bhasma in cancer treatment has garnered increasing interest due to its potential as an alternative therapeutic approach. Bhasma, a herbo-mineral formulation that consists of bioactive nanoparticles used in traditional Indian medicine, has shown promising preclinical evidence for its anticancer properties. Ayurveda, an ancient medicine system practiced in the Indian subcontinent, has successfully used various formulations to prevent or treat arbuda, which can be correlated with cancer. These formulations include Swarna Bhasma, Heerak Bhasma, Abhrak Bhasma, Manikya Bhasma, Yashada Bhasma, and many more. Using Ayurvedic medicines, the side effects of chemotherapy can be minimized, thereby increasing the life span of patients. With the advent of nanotechnology, traditional drug design and delivery are being looked upon in a completely new perspective. The anticancer activity of certain Bhasma is attributed to the presence of metallic nanoparticle content, enhancing its bioavailability and targeted action on cancer cells. In preclinical studies, some Bhasmas have demonstrated potential in inhibiting cancer cell proliferation, inducing apoptosis, and suppressing tumor growth. However, at the same time, limitations in the use of Bhasma for cancer treatment, such as the lack of standardized synthesis processes and documented scientific validation, have also been acknowledged. The multifaceted analysis presented underscores the need for rigorous research, including clinical trials, to validate the safety, efficacy, and specific applications of Bhasma in different cancer types and stages. Although the health-beneficial effects of these Bhasmas have been known for a long time, their mechanism of action is not clearly understood yet at least for some Bhasmas that have shown potential in clinical trials. Therefore, further detailed studies are needed to understand the therapeutic mode of action for different Bhasma. However, despite these limitations, the integration of Ayurvedic Bhasma into cancer treatment regimens emerges as a compelling prospect, potentially yielding synergistic effects.

COMPREHENSIVE STUDY ON THE TOXICOLOGICAL EVALUATION OF AYURVEDIC MEDICATIONS: A CASE OF YASHADA BHASMA AND YASHADA PUSHPA BHASMA IN SWISS ALBINO MICE

Ayurveda, an ancient system of medicine rooted in India, offers a treasure trove of herbal and mineral formulations. Yashada Bhasma1 and Yashada Pushpa Bhasma are two formulations that have gained popularity for their potential therapeutic properties. Traditional Ayurvedic medicines, such as Yashada Bhasma, have been used for centuries to treat various ailments. However, with the surge of interest in Ayurvedic medicine, there is a growing need for rigorous scientific assessments to evaluate their safety and efficacy. This study assessed the subacute toxicity of traditional Ayurvedic medicines, Yashada Bhasma and Yashada Pushpa Bhasma, in Swiss albino mice. This paper presents the results of a comprehensive toxicological study conducted on Swiss albino mice to determine the safety profiles of Yashada Bhasma and Yashada Pushpa Bhasma. These findings underscore the importance of proper dosing and further research, facilitating the safe and effective use of these traditional Ayurvedic preparations in modern healthcare.

TOPICAL MANAGEMENT OF NON-HEALING WOUND WITH PROPRIETARY AYURVEDIC CREAM FORMULATION: A CASE STUDY

A chronic non-healing wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time the way most wounds do; wounds that do not heal within three months are often considered chronic. Chronic wounds are difficult to heal and take their own time to do so. These wounds cause patients severe emotional and physical stress and create a significant financial burden on patients and the whole healthcare system. Non-healing ulcers i.e., Dushta vrana mentioned in Ayurveda can be treated effectively with the help of Ayurvedic formulations. Based on the line of treatment prescribed in the Samhitas, a proprietary Ayurvedic formulation Heal+ Cream was developed that includes- Jatyadi Tail, Vrana Ropan Tail, Panchavalkala, Mandukaparni (Centella asiatica), Yashtimadhu (Glycyrrhiza glabra), Nimb (Azadirachta Indica), Lodhra (Symplocos racemosa), Lajjalu (Mimosa pudica), Shala (Shorea robusta), Yashada bhasma (Zinc oxide) and used to treat such a patient of non-healing Wound in this case study. A case study revealed that Heal+ cream is having mode of action collaborated with Vrana shodhan, Vrana ropan, anti-inflammatory, analgesic, and antibacterial. After the use of Heal+ Cream, the patients with non-healing wounds showed significant improvement regarding the healing of the Wound without any adverse local effects with the restoration of skin structures and health.

A Critical Review on Method of Preparation of Tridhathu Garbha Pottali Rasayana

In Rasashastra all the formulations are primarily divided into four groups viz., Kharaliya rasayana, Parpati rasayana, Kupipakwa Rasyana and Pottali Rasayana. Pottali kalpana, one of the above-mentioned rasa rasayanas, has many qualifications, including minimal product waste, minimal drug dosage, rapid efficacy, and high potency in comparison to other Rasayogas. Tridhatu Garbha Pottali is a Sagandha, Sagni, Gandhakajarita, Kajjali bandha Pottali Kalpana containing Swarna, Naga Bhasma, Vanga Bhasma, Yashada Bhasma, Parada and Gandhaka processed in appropriate temperature. As described by Pandit Hariprapannaji in Rasa Yoga Sagar, this is a rare, one of a kind, potent, cost-effective, novel molecule with highly prospective therapeutic applications, particularly in Prameha, Putimeha, Pradararoga, and Shukradosha.

Pharmaceutico-Analytical Study of Vanaspati Jarita Marita Yashada Bhasma

Yashada is one of the Sapta dhatu, which is chemically Zn, Yashada bhasma is used therapeutically in many diseases like Prameha, Pandu, Vatavyadi etc., in the form of Bhasma (ZnO). Objectives: To prepare Yashada bhasma and its physico-chemical analysis of Yashada bhasma. Materials and Methods: Yashada was subjected Samanya Shodhana, Vishesha Shodhana and Jarana as per Rasatarangini. Yashada marana was done as per Rasayana sara. Bhasma was subjected to physico-chemical analysis which mainly included classical Bhasma parikshas like Rekhapurnata, Varitara, Unama, Nischandrata etc and modern parameters like Acid Insoluble Ash, pH, Total Ash value etc and advanced analytical techniques like XRD, SEM and AAS. Results: After 1st Puta pale yellow colored Yashada bhasma passed classical Bhasma parikshas. In classical reference two Puta are mentioned so, the 2nd Puta was given. XRD reports shows major peaks which were identified as Zinc oxide (ZnO) compound. Hence indicates complete transformation of metal to Bhasma form. Scanning electron microscopy in Yashada Bhasma after 2nd Puta the particle size ranging from 5-10μm. AAS reports shows zinc percentage of 77.08% after 2nd Puta. Conclusion: Pale yellow coloured Yashada bhasma was prepared after two Gaja putas which passed the classical Bhasma parikshas.

Comparing the Physico-Chemical Characteristics of Formulated and Marketed Yashada Bhasma

The present study is aimed to observe the difference in the Physico-Chemical characteristics of the marketed and formulated bhasma samples through X-Ray Diffraction analysis (XRD), Dynamic Light Scattering (DLS), Zeta potential, Thermo-Gravimetric analysis (TGA), Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray analysis (EDAX), apart from organoleptic methods. Inductively Coupled Plasma Mass Spectroscopy (ICPMS) analysis was also done to observe the presence of trace and heavy metals so that the safety of all these samples could be ensured. XRD shows variation in oxide nature of zinc as well crystallite size in all bhasma samples. DLS and SEM results show difference in particle size of marketed bhasma samples as compared to formulated Yashada bhasma. EDAX and ICPMS also confirm the alteration in elemental composition of all these bhasma samples. Thus, it can be concluded that these ayurvedic medicines should be prepared strictly using the formulation methods as mentioned in the Ayurvedic texts. This will help the prepared products to adopt the inherent quality of the ancient system of medicine, which shall be useful and devoid of any side effects for human consumption.

Ayurvedic metal nanoparticles could be novel antiviral agents against SARS-CoV-2.

Purpose of reviewThe pandemic COVID-19 has affected more than seventy million people globally. The whole world is eagerly waiting for an effective antiviral therapy to combat COVID-19, but it is yet to get. The emergence of COVID-19 makes imperative the need for safe and potent antiviral drugs. Many metal nanoparticles exhibit significant antiviral potential against many viral diseases. The Ayurvedic system of medicine is the treasure of many metal nanoparticulate drugs termed as Bhasma.Recent findingsGold, silver, copper, zinc and iron oxide nanoparticles are effective against coronavirus. A possible mechanism of action of the metal nanoparticles against coronavirus is a disruption of outer layers of coronavirus. Swarna Bhasma, Rajata Bhasma, Tamra Bhasma and Yashada Bhasma are recommended for COVID-19 treatment due to the ability to reduce the plasma interleukins, interferons and TNFα levels.SummaryThe Ayurvedic Bhasma preparations are unique metal nanoparticles. These metal nanoparticles are safe, stable in solid state and are having excellent biological activities. Ayurvedic metal nanoparticles, Swarna Bhasma, Rajata Bhasma, Tamra Bhasma and Yashada Bhasma could be proved as novel antiviral agents against SARS-CoV-2 for their anti-inflammatory, immunomodulatory, antiviral and adjuvant activities.

Appraisal of Preventive and Curative Outcome of Yasad Bhasma in Anemic Children.

Introduction: In Ayurveda, lot of drugs have been mentioned to treat Anemia (Pandu roga) and is supposed to treat the disease relatively early and more rationally. Yashad Bhasma is considered as one of the drug to treat anemia disease of children in terms of improvement in hemoglobin, serum iron etc. Aim: The aim of the study was to find out the effect of Yashada Bhasma in anemic children when given with or without iron salt (ferrous Ascorbate) as well as in diseased children. Methodology: All the cases were registered from the O.P.D./I.P.D. of department of Kaumarbhritya/Bal Roga, FOA, IMS, BHU, after getting written informed consent from either parents or guardian of the baby/ child. The study protocol was approved by the PG Medical Board of FOA, IMS, BHU and ethical committee of IMS, BHU. Observation and Result: Mean serum iron level was seems to be increased in group –‘A’ after first follow up and on final follow up but on inter group comparison increase in serum iron level was more consistent and significant (t value of group A & B =4.6 Vs 12.43 and 7.53 Vs 8.78 respectively) in group B than others. Discussion: Serum iron has better improvement in, when give iron along with Yashad bhasma rather than only iron. The present study also clarifies that incidence of URTI (upper respiratory tract infection), diarrhea associated with fever is found reduced at first follow up and maximum reduced in group-C. After final follow up patients of A, B & C do not show onset of any sign and symptoms of any disease.

Safety of Ayurvedic Metal Origin Bhasma (Dhatu varga) through Acute Toxicity Studies: A Review

Bhasma possess broad-spectrum therapeutic utility but are blamed due to frequently raising toxicity concerns. Although their safety has been evident with practice since ancient times, scientifically proven through toxicity studies, clinical safety, still comprehensive conclusive documentation is needed. Online published research articles on in vivo, oral single dose, acute toxicity studies on Bhasma of Dhatu Varga were searched through search engines and observations on behavioural, ponderal, autopsy, maximum tolerated dose (MTD), LD 50 and safety were summarized. Total 11 published paper of acute toxicity study of Dhatu Bhasma (Rajata Bhasma (RB)-1, Tamra Bhasma (TB)-3, Vanga Bhasma (VB)-3, Naga Bhasma (NB)-1, Yashada Bhasma (YB)-1, Loha Bhasma (LB)-1, Trivanga Bhasma-1 were found in rat (Wistar Albino-2, Charles Foster albino-1, Albino-1 total-4) and mice (Swiss Albino-1, Albino-1 total-3) models, MTD and LD 50 of RB are 1500 and >2000 mg/kg, three out of eighteen mice died on day 11. LD 50 of LB and NB is >4160 mg/kg, with honey and also > than 40 and 100 time of TED, respectively. TB (Kajjali (black sulphide of mercury), Gandhaka marit-Shuddha, (purification) Ashuddha, with and without Amritikarana) has LD 50 > 2000 mg/kg licked with honey and it is > 40 TED in Hingula, Gandhaka Marita TB. YB (30 Kukkuta Puta (calcination) up to 300 mg/kg (100 times TED) and YB (Parada pishti, Gandhaka Marit) > 40 TED) is safer. Vastraputi VB up to the 2000 mg/kg (40 TED) and VB (Parada Pishti, Hartala and Jarit Vanaspati Marit by 3, 4 and 7 Puta (calcination), respectively) at 400 mg/kg are safe. Bhasma of Rajat, Loha, Tamra, Yashada, Naga and Vanga are safe at behavioural and some at ponderal, autopsy level through per oral single dose, in vivo acute toxicity studies in rat and mice at 2000, 4160, 2000, 300, 4160 and 2000 mg/kg body weight of animals which are up to 100 times of TED. Keyword: Safety, Ayurveda, Bhasma, acute toxicities, maximum tolerated dose (MTD), clinical safety Cite this Article Pravin Jawanjal, Prashant Bedarkar, Biswajit Patgiri, S.S. Savrikar. Safety of Ayurvedic Metal Origin Bhasma (Dhatu varga) through Acute Toxicity Studies: A Review. Research & Reviews: A Journal of Toxicology . 2019; 9(3): 43–50p.

Physico-chemical characterization of traditionally prepared Yashada bhasma

BackgroundYashada bhasma has been found to be very useful for the treatment of ailments like diabetes, eye disorder, urinary disorder etc. Since bhasma is a metallic preparation, so to prove its non-toxicity; modern standardization of the prepared samples is a must apart from other organoleptic tests as mentioned in the ancient text. ObjectivesThe present study is aimed to synthesize bio-compatible Yashada bhasma from bio-incompatible zinc metal. Further, comparative study of their chemical and physical properties through some quality control tests, physico-chemical tests and modern tests like XRD, DLS, Zeta potential, SEM and EDAX are carried out. Materials and methodsYashada bhasma is prepared by a three step process i.e. Shodhan, Jarana and Marana. The inclusion of plant extracts and herbs during calcination process enhances its medicinal qualities, and reduces it to a nano size. ResultsThe XRD analysis of Yashada bhasma shows hexagonal ZnO crystalline phase whereas the raw metal confirms the presence of crystallite Zinc metal. DLS shows reduction in particle size of Yashada Bhasma (339.8 nm) as compared to raw metal (2063 nm) and this reduction is further supported by SEM which shows the particle size of Yashada bhasma (324 nm) and raw metal (1-2μ). The zeta potential value confirms the stability of Yashada bhasma. EDAX revealed difference in concentration of Zinc and Oxygen in both the samples. ConclusionAn effort has been made to characterize the preparation of Yashada bhasma using sophisticated analytical tools as a step towards standardization of the bhasma. The results help in scientifically establishing the findings in line with the principle of Ayurveda.

Anticancer activity of Yashada Bhasma (bioactive nanoparticles of zinc): A human pancreatic cancer cell line study.

Background:Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer-related mortality. Efforts to improve cancer treatment through nanotechnology are at the developmental stage, and it will be gracious if the drug with anticancer property itself is a nanoparticle. Bhasma is organomineral complexes which are bioactive nanoparticles. Yashada Bhasma (incinerated processed zinc) is widely used in Ayurveda for various diseases, and there are evidence that ZnO nanoparticles are promising antitumor agent. However, no studies have been conducted on the effectiveness of Yashada Bhasma in pancreatic cancer.Materials and Methods:Two types of test drugs, Parada Marita Yashada Bhasma (PMY) and Vanaspati Jarita Marita Yashada Bhasma (JMY), were prepared as per the guidelines of pharmaceutics of Ayurveda. Particle size analyses of Yashada Bhasma and Zeta potential study was carried out initially. Further human pancreatic cancer cell line (MIA PaCa-2) study was done using in vitro sulforhodamine B assay, keeping adriamycinas control. After 48 h of incubation, antiproliferative effects were assessed.Results:JMY and adriamycin showed dose-dependent growth inhibition of cancer cells. Both Yashada Bhasma samples showed a cytostatic effect at this concentration.Conclusion:The study leads to new avenues for cancer treatment by developing such unique and highly effective bioactive nano-sized therapeutic agent.

A Case Report on Pressure Ulcer

Pressure ulcer in an otherwise sick patient and individuals with traumatic paraplegia is a matter of concern for the care givers as well as the medical personnel. Complication caused by pressure ulcers, especially for debilitated elderly patients will be life threatening one. In this report, we describe the successful use of Mrudupratisaraneeya Apamarga Kshara Karma and Hamsapadi Taila to treat pressure ulcer. A 68-year-old woman visited our hospital who had presented with complex pressure ulcers at the level of L5, S2 and on the sacrococcygeal region with discharge of pus since 4 months. She was Cardiomyopathic. She had suffered from Right hemiparasis and Facial palsy 2yrs back and treated for the same in Narayana Hrudayalaya for 10 days and while discharging she had expressive aphasia and was ambulatory with minimal support. Her medical history confirmed pressure ulcer and we started with Mrudupratisaraneeya Apamarga Kshara Karma followed by Hamsapadi Taila dressing, final closure of wound occurred after 4 months. Mrudupratisaraneeya Kshara Karma with Hamsapadi Taila + Yashada Bhasma is an effective treatment protocol and it can reduce the healing time of the pressure ulcer.

Adaptogenic potential of Oxitard in experimental chronic stress and chronic unpredictable stress induced dysfunctional homeostasis in rodents

BackgroundOxitard, a polyherbal formulation comprising the extracts of Withania somnifera, Mangifera indica, Glycyrrhiza glabra, Daucus carota, Vitis vinifera, powders of Syzygium aromaticum, Yashada bhasma and Emblica officinalis; and oils of Triticum sativum. ObjectiveCurrent study deals with the assessment of Oxitard (a marketed polyherbal formulation) for its adaptogenic potential in chronic unpredictable stress (CUS) and chronic stress (CS) induced dysfunctional homeostasis in rodents. Materials & methodsAnimals were immobilized for 2 h every day for ten days to induce CS. In order to induce CUS, animals were employed in a battery of stressors of variable value and duration for ten days. Following administration of Oxitard, stress was induced in the animals. Stress-induced efficient changes were evaluated by assessing organ (adrenal gland) weights, ulcer index, hematological parameters and biochemical levels of reduced glutathione (GSH), thiobarbituric acid reactive substances (TBARS) and catalase (CAT). ResultsCS and CUS significantly modified the oxidative stress parameters (increased MDA and decreased GSH). Furthermore, CS and CUS lead to weight reduction, adrenal hypertrophy and gastric ulceration. Pre-treatment with Oxitard (200 and 400 mg/kg, p.o.) significantly modified CS and CUS induced hematological changes, oxidative stress parameters and pathological effects. ConclusionIn conclusion, Oxitard-intervened antioxidant actions are accountable for its adaptogenic effects in stress-induced dysfunctional homeostasis.

SOME OBSERVATIONS OF THE ZINC-METALS BASED PREPARATIONS AND ITS PROPERTIES IN AYURVEDA WITH REGARD TO STABILITY OF MEDICINES IN THE NANO STATE

In Indian system of medicine, herbo - mineral/ m etallic formulation s are used since 2 nd Century. However, the scarcity of complete scientific evaluation of their physic o - chemical c haracterization, therapeutic efficacy and stability study is t he major cause for creating hindrance in their acceptance at global lev el . It is a thinking of modern pharmaceutical scientist, that expiry date express on Ay urvedic medicine is arbitrary. This paper will briefly explore the physic o - chemical properties of two different samples of Yashada Bhasma prepared at a time interval of 12 years . During different pharmaceutical process temperature was recorded w ith non - contact pyrometer. The p resence of different elements was determined by Energy dispersive X - ray analy sis (EDAX). The surface morphology as well as the nanoparticles nature was observed by scanning electron microscopy (SEM). The crystalline nature of Bhasma was assessed by powdered X - ray diffractom etry . This study revealed that both the formulations have n early same findings in different parameter s considered for study and even after the passage of 12 years the Bhasma didn't show any significant change s .

Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation).

Introduction:Laghu Malini Vasanta (LMV) Rasa is a well-known Vasanta Kalpa (formulation). As per reference of Yoga Ratnakara, Rasaka and Maricha are chief ingredients in 2:1 proportion. Bhavana (levigation) is said to be given first with Navaneeta (freshly prepared cow's butter) and then with Nimbu Swarasa (lemon juice) until Ghrita Vimukta stage is reached. Quantity of Bhavana Dravya (levigating media) and duration of levigation are not mentioned.Aims:To develop standard manufacturing procedure of LMV Rasa.Materials and Methods:The study was carried out in two stages - preparation of Yashada Bhasma and preparation of LMV Rasa and its tablet. A pilot study was carried out to fix quantity of cow's butter as levigation media. Based on results of the pilot study, LMV Rasa was prepared in two groups, that is, LMV 50 (LMV Rasa - prepared with weight of freshly prepared butter in 50% quantity of total ingredients) and LMV 75 (LMV Rasa prepared with weight of freshly prepared butter in 75% quantity of total ingredients). Complete drying of levigated mass and minimal spreading of fatty portion on filter paper was considered as the end point of levigation. Tablets of both samples were prepared by adding Pippali and honey in it and analyzed for their quality control parameters.Results:Twenty-eight hours duration of repeated levigation was required in LMV 50 which was prolonged up to 48 h in batch carried out in rainy season. In LMV 75, comparatively maximum duration of 54 h was required for levigation which was prolonged in the rainy season to 88 h. In both groups, lemon juice required for repeated levigation was 10 times of quantity of butter added initially.Conclusion:From pharmaceutical point of view, preparation of LMV Rasa tablets with quantity of butter in 50% of total ingredients is more convenient.

Yashada bhasma (Zinc calx) and Tankana (Borax) inhibit Propionibacterium acne and suppresses acne induced inflammation in vitro.

Yashada bhasma (YB) and Tankana (TA) are well characterized minerals used in traditional medicine for the treatment of various skin ailments. Yashada bhasma and TA are a unique preparation of zinc and borax, respectively. The study was conducted to evaluate the in vitro inhibitory effect of YB, TA and its combination (YBTA) on Propionibacterium acne growth and P.acne-induced inflammation. The minerals were tested for anti-P.acne activity by disc diffusion and broth microdilution methods. The effect of these minerals on P.acne induced TNF-α and IL-8 production and gene expression were studied in THP-1 cells. In vitro toxicity was tested on human keratinocytes (HaCaT) and mouse embryonic fibroblasts (NIH3T3) using MTT assay. The minimum inhibitory concentrations (MIC values) for YB, TA and YBTA against P.acne were 0.1±0.2, 1.9±0.5 and 0.3±0.5mgmL(-1) , respectively. YB, TA and YBTA inhibited TNFα by 57.57%, 59.09% and 68.93% and IL-8 production by 48.76%, 47.92% and 51.13% in P.acne-stimulated THP-1 cells, respectively. The CTC50 values on HaCaT and NIH3T3 was 17.44±0.5 and 16.37±0.2μgmL(-1) for YB, 1023.03±4.0 and 1286.17±4.4μgmL(-1) for TA and 89.12±2.3 and 111.58±3.5μgmL(-1) for YBTA, respectively. The present study revealed the inhibitory effect of YB, TA and YBTA on P.acne growth and inflammation. Clinical studies have suggested the anti-acne benefits of formulations containing YB and TA. The findings obtained from the present in vitro studies provide evidence to support the mechanism of anti-acne properties of YB and TA.

Analytical Study of Yashada bhasma (Zinc Based Ayurvedic Metallic Preparation) with reference to Ancient and Modern Parameters

Analytical Study of Yashada bhasma (Zinc Based Ayurvedic Metallic Preparation) with reference to Ancient and Modern Parameters

Evaluation of market samples of ′Yashada bhasma′ using ′Namburi Phased Spot Test′

Yashada bhasma (Calx of Yashada i.e. Zinc) which has its main indication in Prameha (Diabetes) and Netra vikaras (Eye disorders) was prepared according to the prescription in the Ayurvedic classics and subjected to various bhasma parikshas, including the Namburi Phased Spot Test (NPST), one of the qualitative tests described for various Ayurvedic preparations. NPST helps differentiate between, and thus identify, various bhasmas. It depends upon the pattern of the spot, which develops after a specific chemical reaction. Three market samples of Yashada bhasma, which were said to be Parada marita (incinerated using Mercury), were also subjected to the above tests and results compared. The various bhasmas exhibited marked differences in colour, and though NPST yielded desired results for all the samples, there were differences in their spot patterns and colour. The bhasma prepared in our department produced the most accurate results.