Abstract Paleogeographic reconstructions are of key importance for understanding the history of continental breakups and amalgamations during the whole history of the Earth. A special case is the history of the Asian continent, which, compared to other continents, consists of several large cratons and numerous smaller continental blocks. The history of the assembly of South China remains controversial in terms of the timing, Late Neoproterozoic or Early Paleozoic, and the participating continental blocks, e.g., Yangtze, Cathaysia, India and/or Australia. Detrital rutile U-Pb dating possesses a significant potential for deciphering tectonic settings as rutile frequently crystallizes during orogenic events associated with the processes of collision and subduction. Detrital zircon U-Pb dating is a perfect instrument for identifying provenance characteristics and age characteristics of sedimentary sources. An integration of these two methods of dating offers better opportunities for reconstructing tectonic settings. This paper presents a first attempt to reconstruct the Neoproterozoic to Early Palaeozoic tectonic history and paleogeography of the whole South China Block based on U-Pb geochronology of rutile and zircon and Hf-in-zircon isotopes from Lower Jurassic Baitianba Formation sedimentary rocks of the western margin of the Yangtze Block, a major part of South China. Our obtained integrated U-Pb rutile and zircon age data show three main age populations of 960-940 Ma, 630-610 Ma and 530-520 Ma. The new U-Pb detrital rutile and zircon ages, compared with former data from Gondwana and Australia, suggest that Yangtze amalgamated with Cathaysia to form South China during the Sibao orogeny at 960-940 Ma. The detrital rutile and zircons of the new 630-610 Ma age group could have been delivered from western Australia during Late Neoproterozoic to Cambrian Paterson-Petermann orogeny. The abundant 530-520 Ma detrital rutile and zircon ages fit well the coeval zircon age populations recorded in Gondwana-derived terranes, like India and Indochina.