The first distributed feedback (DFB) dye laser on the basis of microporous quartz glass (MQG) is reported. MQG consists of a specially processed quartz sample doped with a dye. As a pumping source a second harmonic YAG: Nd3+ laser with 12.5 pps repetition rate was used. Stable generation of the narrow line tuned within a spectral range of 562–584 nm and 633–663 nm with a linewidth of 0.04 nm was obtained. A high photochemical stability of the dye in the quartz matrix and reliability of MQG as an active medium for the tunable DFB laser were experimentally demonstrated.