To study the distribution characteristics of atmospheric pollutants and their correlation with meteorological factors. The PM_(2.5), PM_(10), NO_2, SO_2, O_(3-1 h), O_(3-8 h) and CO daily average concentration data from 2014 to 2020 were obtained from Lanzhou Environmental Protection Bureau. The interannual changes of pollutants, monthly changes, seasonal changes and trend of spatial distribution were analysed. Spearman correlation analysis was performed on the relationship among pollutants. The main pollutants exceeding the standard in Lanzhou from 2014 to 2020 were PM_(10), PM_(2.5) and NO_2, average annual concentration of PM_(10), PM_(2.5), NO_2 and CO were decreasing year by year, and O_3 was increasing year by year. The monthly average concentration of PM_(10) was the highest in December, January, March and November were the second highest, and it was higher in February, April and May. The monthly change trends of PM_(2.5), NO_2, SO_2 and CO concentrations were the same, and the monthly change trends of the 1 hour average and daily maximum 8-hour average concentrations of O_3 were the same. The seasonal variation of atmospheric pollutant concentration was obvious, the concentrations of PM_(10), PM_(2.5), SO_2, NO_(2 )and CO were the highest in winter and the lowest in summer. O_3 concentration was the highest in summer and lowest in winter. Average annual concentration of 6 pollutants in different regions had statistically significant differences(H=750.40, 1112.99, 1410.05, 352.04, 360.17, 619.20, 729.52; P<0.001). Among them, the average annual concentration of PM_(10), PM_(2.5), SO_(2 )and O_(3-1 h) in Xigu District were the highest. PM_(10), PM_(2.5), NO_2, SO_2, CO average annual concentration were negatively correlated with temperature and wind speed(r_s=-0.423, -0.561, -0.395, -0.660, -0.569, -0.043, -0.094, -0.130, -0.172, -0.135), the concentration of PM_(10), PM_(2.5), O_3, SO_2 concentration were negatively correlated with humidity(r_s=-0.238, -0.121, -0.110, -0.094), only O_3 was positively correlated with temperature(r_s=0.486). The primary pollutants in Lanzhou from 2014 to 2020 were PM_(10), PM_(2.5) and NO_2.O_3 had an obvious upward trend year by year. The 6 pollutants had obvious seasonal changes and regional distribution characteristics. Some pollutants had the same homology, and meteorological factors affected each pollution. The concentration of the substance had an important influence. Relevant air pollution control measures should be formulated based on the main excessive pollutants, the monthly change trend of air pollution and the seasonal pollution characteristics, the same emission sources and geographical distribution characteristics should be considered, and the meteorological factors should be combined.