The stratigraphic succession of a forearc basin provides crucial information on the history of a convergent plate margin. In particular, it helps to establish the origin of the underlying ophiolites and to unravel the earliest evolutionary stage of arc-trench systems, which remain poorly understood. The Xigaze forearc basin in southern Tibet is one of the best examples of a fossil forearc basin. This study illustrates detailed stratigraphic and high-precision SIMS U–Pb zircon geochronological and Hf isotopic data from the Chongdui Formation, representing the very base of the Xigaze forearc-basin succession, and reconstructs when and how the basin was formed. The Chongdui Formation includes tuffaceous chert and siliceous mudrocks deposited directly on top of pillow basalts of the Xigaze ophiolite and conformably overlain by volcaniclastic turbidites. Tuff layers are interbedded throughout the unit, and their U–Pb zircon ages range from 119 to 113 Ma in the lower member and from 113 to 110 Ma in the upper member, broadly consistent with the established radiolarian biostratigraphy. U–Pb ages and Hf isotope signatures of zircons contained in both tuff layers and turbiditic sandstones indicate clear affinity with magmatic rocks of the Lhasa terrane. Direct depositional and chronostratigraphic relationship with the underlying oceanic crust, dated between 131 and 124 Ma, proves that the Xigaze ophiolite is the basement of the Xigaze forearc basin. After an initial prolonged stage of starved siliceous sedimentation, influx of terrigenous detritus began at 113–110 Ma, reflecting the onset of topographic growth and erosion of the Lhasa terrane in response to intense magmatic activity. Formation of the ophiolitic basement during the early stage of subduction and the subsequent topographic growth of the arc source induced by subduction-related magmatism are thus two critical factors for the birth of the Xigaze forearc basin. Similar stratigraphies were identified in the Great Valley and Luzon Central Valley forearc basins, suggesting that the initial geodynamic evolution of the Xigaze forearc basin may be common to many other forearc basins worldwide.