X-ray Source Research Articles

Laboratory x-ray nano-computed tomography for biomedical research

High-resolution x-ray tomography is a common technique for biomedical research using synchrotron sources. With advancements in laboratory x-ray sources, an increasing number of experiments can be performed in the lab. In this paper, the design, implementation, and verification of a laboratory setup for x-ray nano-computed tomography is presented using a nano-focus x-ray source and high geometric magnification not requiring any optical elements. Comparing a scintillator-based detector to a photon counting detector shows a clear benefit of using photon counting detectors for these applications, where the flux of the x-ray source is limited and samples have low contrast. Sample contrast is enhanced using propagation-based phase contrast. The resolution of the system is verified using 2D resolution charts and using Fourier Ring Correlation on reconstructed CT slices. Evaluating noise and contrast highlights the benefits of photon counting detectors and the contrast improvement through phase contrast. The implemented setup is capable of reaching sub-micron resolution and satisfying contrast in biological samples, like paraffin embedded tissue.

Multiwavelength identification of millisecond pulsar candidates in the Galactic bulge

Context. The existence of a population of millisecond pulsars in the Galactic bulge is supported, along with other evidence, by the Fermi GeV excess, an anomalous γ-ray emission detected almost 15 years ago in the direction of the Galactic center. However, radio surveys searching for pulsations have not yet revealed bulge millisecond pulsars. Aims. Identifying promising bulge millisecond pulsar candidates is key to motivating pointed radio pulsation searches. Candidates are often selected among steep-spectrum or polarized radio sources, but multiwavelength information can also be exploited: The aim of this work is to pinpoint strong candidates among the yet unidentified X-ray sources. Methods. We investigated the multiwavelength counterparts of sources detected by the Chandra X-ray observatory that have spectral properties expected for millisecond pulsars in the Galactic bulge. We considered that ultraviolet, optical, and strong infrared counterparts indicate that an X-ray source is not a bulge pulsar, while a radio or a faint infrared counterpart makes it a promising candidate. Results. We identify a large population of more than a thousand X-ray sources without optical, ultraviolet, or strong infrared counterparts. Among them, five are seen for the first time in unpublished radio imaging data from the Very Large Array. We provide the list of promising candidates, for most of which follow-up pulsation searches are ongoing.

Dual-Domain Collaborative Diffusion Sampling for Multi-Source Stationary Computed Tomography Reconstruction.

The multi-source stationary CT, where both the detector and X-ray source are fixed, represents a novel imaging system with high temporal resolution that has garnered significant interest. Limited space within the system restricts the number of X-ray sources, leading to sparse-view CT imaging challenges. Recent diffusion models for reconstructing sparse-view CT have generally focused separately on sinogram or image domains. Sinogram-centric models effectively estimate missing projections but may introduce artifacts, lacking mechanisms to ensure image correctness. Conversely, image-domain models, while capturing detailed image features, often struggle with complex data distribution, leading to inaccuracies in projections. Addressing these issues, the Dual-domain Collaborative Diffusion Sampling (DCDS) model integrates sinogram and image domain diffusion processes for enhanced sparse-view reconstruction. This model combines the strengths of both domains in an optimized mathematical framework. A collaborative diffusion mechanism underpins this model, improving sinogram recovery and image generative capabilities. This mechanism facilitates feedback-driven image generation from the sinogram domain and uses image domain results to complete missing projections. Optimization of the DCDS model is further achieved through the alternative direction iteration method, focusing on data consistency updates. Extensive testing, including numerical simulations, real phantoms, and clinical cardiac datasets, demonstrates the DCDS model's effectiveness. It consistently outperforms various state-of-the-art benchmarks, delivering exceptional reconstruction quality and precise sinogram.

X-Ray Bright Active Galactic Nuclei in Local Dwarf Galaxies: Insights from eROSITA

Although supermassive black holes (SMBHs) reside in the heart of virtually every massive galaxy, it remains debated whether dwarf galaxies commonly host SMBHs. Because low-mass galaxies may retain memory of the assembly history of their black holes (BHs), probing the BH occupation fraction of local dwarf galaxies might offer insights into the growth and seeding mechanisms of the first BHs. In this work, we exploit the Western half of the eROSITA all-sky survey (covering 20,000 deg2) and compile a catalog of accreting SMBHs in local (D < 200 Mpc) dwarf galaxies. Cleaning our sample from X-ray background sources, X-ray binaries, and ultraluminous X-ray sources, we identify 74 active galactic nucleus (AGN)–dwarf galaxy pairs. Using this large and uniform sample, we derive the luminosity function of the dwarf galaxy AGN, fitting it with a power-law function and obtaining dN/dLX=(15.9±2.2)×LX−1.63±0.05 . Measuring the offset between the dwarf galaxies' centroids and the X-ray sources, we find that ≈50% of the AGN are likely off-nuclear, in agreement with theoretical predictions. We compare the BH-to-stellar mass relation of our sample with the local and high-redshift relations, finding that our sources better adhere to the former, which suggests that local AGN across different mass scales undergo similar growth histories. Finally, we compare our sources with semianalytical models: while our sample’s shallowness prevents distinguishing between different seeding models, we find that the data favor models that keep SMBHs in dwarf galaxies active at a moderate rate, motivating model improvement by comparison to AGN in the dwarf galaxy regime.

Measurements of K-edge and L-edge extended x-ray absorption fine structure at the national ignition facility (invited).

High-energy-density laser facilities and advances in dynamic compression techniques have expanded access to material states in the Terapascal regime relevant to inertial confinement fusion, planetary science, and geophysics. However, experimentally determining the material temperature in these extreme conditions has remained a difficult challenge. Extended X-ray Absorption Fine Structure (EXAFS), referring to the modulations in x-ray absorption above an absorption edge from photoelectrons' interactions with neighboring atoms, has proven to be a versatile and robust technique for probing material temperature and density for mid-to-high Z elements under dynamic compression. The current platform at the National Ignition Facility has developed six configurations for EXAFS measurements between 7 and 18keV for different absorption edges (Fe K, Co K, Cu K, Ta L3, Pb L3, and Zr K) using a curved-crystal spectrometer and a bright, continuum foil x-ray source. In this work, we describe the platform geometry, x-ray source performance, spectrometer resolution and throughput, design considerations, and data in ambient and dynamic-compression conditions.

The influence of miscentering on radiation dose during computed tomography head examinations and the role of localiser orientation: A phantom study

IntroductionComputed Tomography (CT) chest, abdomen and pelvis research demonstrates a relationship between vertical phantom positioning and radiation dose. Moving the phantom closer or further from the x-ray source results in magnification or minimisation of the localiser. As automatic tube current modulation (ATCM) algorithms use localisers to estimate patient size and calculate required tube current, magnification or minimisation results in the incorrect provision of radiation dose. Radiation dose changes also depend on localiser orientation, changes with anteroposterior (AP) and posteroanterior (PA) localisers demonstrating an inverse relationship. However, within CT head literature often attributes radiation dose changes on impaired function of the bow-tie filter instead. The current study investigated the role of miscentering on ATCM function within CT head, paying particular attention to localiser orientation. MethodsHead scanning was performed with an anthropomorphic phantom at the isocentre, alongside ten vertically miscentered positions. This was performed three times, with an AP, PA and lateral localiser. CT dose index values at each miscentered level were compared across conditions. ResultsVertical miscentering altered radiation dose in both AP and PA conditions, radiation dose linearly increasing (up to 17.05%) when positioning the phantom closer to the x-ray source and decreasing when positioning away (up to −13.13%). Changes across AP and PA conditions demonstrated an inverse relationship. Radiation dose was unaffected in the lateral condition. ConclusionsMiscentering during CT head alters ATCM function due to magnification/minimisation of the localiser image, causing ATCM algorithms to misinterpret patient size and miscalculate required tube current. Implications for practiceRadiographers should be accurate when centering for CT head, avoiding any potential radiation dose changes. Further research into vertical miscentering and image quality during CT head is recommended.

The operational principles of MICROMEGAS gas detectors at low pressure: A comprehensive exploration

Extensive efforts at INFN Pisa have focused on optimizing a gas detector for low pressures down to 100mbar. MICROMEGAS technology, with its tunable avalanche volume, is inherently suited for these conditions. However initial standard simulations predicted low gain at these pressures. An extensive test campaign with X-ray sources and refined simulations based on experimental results have provided a better understanding of the detector’s performance across different gas pressures.

Searching for the Highest-z Dual Active Galactic Nuclei in the Deepest Chandra Surveys

We present an analysis searching for dual active galactic nuclei (AGN) among 62 high-redshift (2.5 < z < 3.5) X-ray sources selected from the X-UDS, AEGIS-XD, CDF-S, and COSMOS-Legacy Chandra surveys. We aim to quantify the frequency of dual AGN in the high-redshift Universe, which holds implications for black hole merger timescales and low-frequency gravitational wave detection rates. We analyze each X-ray source using BAYMAX, an analysis tool that calculates the Bayes factor for whether a given archival Chandra AGN is more likely a single or dual point source. We find no strong evidence for dual AGN in any individual source in our sample. We increase our sensitivity to search for dual AGN across the sample by comparing our measured distribution of Bayes factors to that expected from a sample composed entirely of single point sources and find no evidence for dual AGN in the sample distribution. Although our analysis utilizes one of the largest Chandra catalogs of high-z X-ray point sources available to study, the findings remain limited by the modest number of sources observed at the highest spatial resolution with Chandra and the typical count rates of the detected sources. Our nondetection allows us to place an upper limit on the X-ray dual AGN fraction at 2.5 < z < 3.5 of 4.8% at the 95% confidence level. Expanding substantially on these results at X-ray wavelengths will require future surveys spanning larger sky areas and extending to fainter fluxes than has been possible with Chandra. We illustrate the potential of the AXIS mission concept in this regard.

Deep learning based x-ray spectrometer for high repetition rate characterization of betatron radiation

Betatron radiation produced from a laser-wakefield accelerator is a broadband, hard x-ray (&amp;gt;1 keV) source that has been used in a variety of applications in medicine, engineering, and fundamental science. Further development and optimization of stable, high repetition rate (HRR) (&amp;gt;1 Hz) betatron sources will provide a means to extend their application base to include single-shot dynamical measurements of ultrafast processes or dense materials. Recent advances in laser technology used in such experiments have enabled increases in shot-rate and system stability, providing improved statistical analysis and detailed parameter scans. However, unique challenges exist at high repetition rate, where data throughput and source optimization are now limited by diagnostic acquisition rates and analysis. Here, we present the development of a machine-learning algorithm for the real-time analysis of betatron radiation. We report on the fielding of this deep learning algorithm for online source characterization at the Institut National de la Recherche Scientifique's Advanced Laser Light Source. By fine-tuning an algorithm originally trained on a fully synthetic dataset using a subset of experimental data, the algorithm can predict the betatron critical energy with a percent error of 7.2 % with a reconstruction time of 1.5 ms, providing a valuable tool for real-time, multi-objective optimization at HRR.

Simultaneous co-axial multi-modal inspection using a laser driven x-ray and neutron source.

Laser-plasma interactions have been demonstrated to produce bright sources of energetic radiation including ions, electrons, photons across the electro-magnetic spectrum, and neutrons. Combinations of species can significantly increase information from non-destructive imaging. Here we demonstrate single-shot co-axial radiography with both x-ray and fast-neutron radiation from a laser-driven source using a pair of gated microchannel plate photomultiplier tube channels and a fast scintillator medium. The outlined system demonstrates recovery full-width-half-maximum of (18 ± 3) ns, which is sufficient to isolate x-rays from neutrons up to (72 ± 20) MeV and could be isolated only a short distance (2m) from the target.

An X-ray fluorescence experimental method for photon-counting detector in computed tomography system

The X-ray fluorescence (XRF) spectrum of specific elements can be utilized in energy calibration, energy resolution measurement, and analysis of energy response functions for photon-counting detectors (PCDs). The applications can be beneficial for PCD threshold accuracy, performance verification, and optimizing image quality. In previous literature, the experimental configuration for the XRF spectrum typically employed a vertical configuration to avoid the influence of the primary X-ray beam. However, such an experimental configuration is constrained by the fixed position of the X-ray source and detector in the computed tomography (CT) system. Hence, the purpose of this study is to investigate a horizontal configuration for XRF measurements and compare the differences in XRF spectrum with vertical configuration. The results indicate that the spectral characteristics of the horizontal and vertical configurations are similar, suggesting that the horizontal configuration could be applied for energy calibration and spectral analysis in PCD-CT systems.

Stripe 82X Data Release 3: Multiwavelength Catalog with New Spectroscopic Redshifts and Black Hole Masses

We present the third catalog release of the wide-area (31.3 deg2) Stripe 82 X-ray survey. This catalog combines previously published X-ray source properties with multiwavelength counterparts and photometric redshifts, presents 343 new spectroscopic redshifts, and provides black hole masses for 1297 Type 1 active galactic nuclei (AGN). With spectroscopic redshifts for 3457 out of 6181 Stripe 82X sources, the survey has a spectroscopic completeness of 56%. This completeness rises to 90% when considering the contiguous portions of the Stripe 82X survey with homogeneous X-ray coverage at an optical magnitude limit of r < 22. Within that portion of the survey, 23% of AGN can be considered obscured by being either a Type 2 AGN, reddened (R − K > 4, Vega), or X-ray obscured with a column density of N H > 1022 cm−2. Unlike other surveys, there is only an 18% overlap between Type 2 and X-ray obscured AGN. We calculated black hole masses for Type 1 AGN that have Sloan Digital Sky Survey spectra using virial mass estimators calibrated on the Hβ, Mg ii, Hα, and C iv emission lines. We find wide scatter in these black hole mass estimates, indicating that statistical analyses should use black hole masses calculated from the same formula to minimize bias. We find that the AGN with the highest X-ray luminosities are accreting at the highest Eddington ratios, consistent with the picture that most black hole mass accretion happens in the phase when the AGN is luminous (L 2−10keV > 1045 erg s−1).

Exploring the nature of an ultraluminous X-ray source in NGC 628

Aims. In this work, we study the X-ray spectral and temporal properties of an ultraluminous X-ray source (ULX) in NGC 628 by using multi-epoch archival X-ray data. The physical parameters were estimated in each epoch in order to constrain the nature of the compact object in the system. Also, the optical counterpart candidates of the ULX were examined using the archival Hubble Space Telescope (HST)/Wide Field Camera 3 (WFC3) data. Methods.XMM-Newton, Chandra, and Swift data were used to create the long-term light curve (which covers a period of 22 years) and perform the spectral analysis. Lomb-Scargle periodograms of the source were constructed to examine the short-term variability in each epoch. In order to search for an optical counterpart in the HST/WFC3 images, a relative astrometric correction was initially applied to the Chandra and HST/WFC3 images. Results. The X-ray flux of the source changes by a factor of ∼200 throughout the observations. The previously detected quasi-periodic signal (in the range of 0.1−0.4 mHz) was confirmed by using the Lomb-Scargle method. After astrometric correction, two optical counterpart candidates were detected for the source. The obtained spectral energy distributions in the optical band for both candidates indicate that the optical emission is dominated by the irradiation of the accretion disc. Considering the best-fit model parameters of the multi-colour disc black-body model, we derived the mass of the black hole in the system as being in the range of (5−28) M⊙. Nonetheless, the long-term variability and the spectral transitions in the hardness–luminosity diagram make it difficult to rule out the neutron star scenario.

Preoperative Planning for Shoulder Arthroplasty is Feasible with Computed Tomography at Lower-Than-Conventional Radiation Doses

Computed tomography (CT) offers a detailed assessment of the shoulder for preoperative shoulder arthroplasty planning; however, this technique exposes the patient to ionizing radiation. The purpose of this study was to prospectively evaluate the practicality of reducing the CT radiation dose compared to conventional dose levels for manual and preoperative planning software measurements for shoulder arthroplasty. A total of 10 shoulder CT examinations were performed for preoperative planning purposes on a dual x-ray source CT scanner. A specialized dose-split scan technique was utilized to reconstruct CT images corresponding to 100%, 70%, and 30% radiation dose relative to our institution's standard of care imaging protocol. Glenoid version, inclination, and humeral head subluxation were measured manually by three authors and by commercially available software platforms. These measurements were analyzed for agreement between the 100%, 70%, and 30% dose levels for each patient. Tolerances of 5° of glenoid version, 5° of glenoid inclination, and 10% humeral head subluxation were used as equivalent for preoperative planning. Automated measurements of 70% dose images were within 5° of version, 5° of inclination, and 10% subluxation in 95.0% of cases. Manual measurements of 70% RD images were within 5° of version for 90.0% of cases, 5° of inclination in 86.7% of cases, and 10% subluxation in 100% of cases. Automated measurements from the 30% dose images were within 5° of version, 5° of inclination, and 10% subluxation for 100% of cases. Manual measurements from the 30% dose images were within 5° of version for 86.7% of cases, 5° of inclination in 76.7% of cases, and 10% subluxation in 100% of cases. The mean absolute difference in software measurement of glenoid version (p = 0.96), glenoid inclination (p = 0.64), or humeral head subluxation (p = 0.09) or in aggregated manual mean absolute difference of version (p = 0.22), inclination (p = 0.31), or humeral head subluxation (p = 0.56) was not significant. Good to excellent reliability was determined by interclass correlation coefficients among the manual observers and automatic software platforms for measurements at all doses (P<0.001) CONCLUSIONS: The results indicate that both preoperative planning software platforms and human observers produced similar measurements of glenoid version, inclination, and humeral head subluxation from reduced-dose images compared to standard of care doses. By implementing reduced dose techniques in preoperative shoulder CT, the potential risks associated with radiation exposure could be reduced for patients undergoing shoulder arthroplasty.

Irradiation-driven mass transfer for massive companion stars in supersoft X-rays sources

Context. Supersoft X-ray sources (SSSs) have been proposed as one of the progenitors for Type Ia supernovae. However, the exact origin of the quasi-periodic variability in the optical light curve remains a mystery. Aims. In this work, our goal is to investigate the effect of the feedback of an evolved main-sequence companion star on X-ray irradiation and find whether periodic X-ray irradiation of the companion star could reproduce periodic mass transfer. Methods. Using the Modules for Experiments in Stellar Astrophysics (MESA) code, we modeled the evolutionary track of the companion star under the influence of supersoft X-ray irradiation, and we calculated the resulting mass transfer rate. Results. We find that the supersoft X-ray heating of the companion star can result in the expansion of the companion, causing it to greatly overflow its Roche lobe and thereby increasing the mass transfer rate. The periodic X-ray irradiation on the companion stars leads to periodic changes in the mass transfer rate. For a given companion star, higher irradiation efficiencies result in a higher mass transfer rate. Additionally, the mass transfer rate increases as the mass of the companion star decreases for a given irradiation efficiency. Conclusions. The companion star undergoing thermal timescale mass transfer is periodically irradiated by the X-rays from the WD, which can lead to periodic enhancement of the mass transfer rate. The mechanism could be the origin of the quasi-periodic optical light curve in supersoft X-ray sources.

A Luminous X-Ray Active Galactic Nucleus in the Dwarf–Dwarf Galaxy Merger RGG 66

We present the discovery of a luminous X-ray active galactic nucleus (AGN) in the dwarf galaxy merger RGG 66. The black hole is predicted to have a mass of M BH ∼ 105.4 M ⊙ and to be radiating close to its Eddington limit (L bol/L Edd ∼ 0.75). The AGN in RGG 66 is notable both for its presence in a late-stage dwarf–dwarf merger and for its luminosity of L 2–10 keV = 1042.2 erg s−1, which is among the most powerful AGNs known in nearby dwarf galaxies. The X-ray spectrum has a best-fit photon index of Γ = 2.4 and an intrinsic absorption of N H ∼ 1021 cm−2. These results come from a follow-up Chandra X-ray Observatory study of four irregular/disturbed dwarf galaxies with evidence for hosting AGNs based on optical spectroscopy. The remaining three dwarf galaxies do not have detectable X-ray sources with upper limits of L 2–10 keV ≲ 1040 erg s−1. Taken at face value, our results on RGG 66 suggest that mergers may trigger the most luminous of AGNs in the dwarf galaxy regime, just as they are suspected to do in more massive galaxy mergers.

A Deeper Look into eFEDS AGN Candidates in Dwarf Galaxies with Chandra

The ability to accurately discern active massive black holes (BHs) in nearby dwarf galaxies is paramount to understanding the origins and processes of “seed” BHs in the early Universe. We present Chandra X-ray Observatory observations of a sample of three local dwarf galaxies (M * ≤ 3 × 109 M ⊙, z ≤ 0.15) previously identified as candidates for hosting active galactic nuclei (AGN). The galaxies were selected from the NASA-Sloan Atlas with spatially coincident X-ray detections in the eROSITA Final Equatorial Depth Survey. Our new Chandra data reveal three X-ray point sources in two of the target galaxies with luminosities between log(L 2−10 keV [erg s−1]) = 39.1 and 40.4. Our results support the presence of an AGN in these two galaxies and an ultraluminous X-ray source (ULX) in one of them. For the AGNs, we estimate BH masses of M BH ∼ 105−6 M ⊙ and Eddington ratios on the order of ∼10−3.

Data quality in laboratory convergent-beam X-ray total scattering

Measurement of laboratory atomic pair distribution function data has improved with contemporary X-ray sources, optics and detectors, with acquisition times of the order of minutes for ideal samples. This paper examines resolution effects in pair distribution function data obtained using a convergent-beam configuration and an Ag X-ray tube from standard silicon powder and from 10 nm BaTiO3 nanocubes. The elliptical multilayer X-ray mirror reflects a non-trivial X-ray spectrum and introduces resolution effects not commonly treated in ordinary parafocusing divergent-beam laboratory diffraction. These resolution effects are modeled using the fundamental parameters approach, and the influence this has on interpretation and modeling of the resulting reduced atomic pair distribution function data is demonstrated.

High brightness betatron x-ray source driven by chirped laser pulses

We demonstrate high brightness betatron x-ray generation from a chirped laser pulses driven plasma accelerator. It is shown that positively chirped laser pulse leads to the initiation and enhancement of collective oscillations of electrons inside plasma bubbles, due to associated pulse front tilt (PFT). The PFT causes transverse drift of the bubbles with respect to the laser axis, which results in high brightness x-ray generation. At an optimum chirp, enhanced x-ray emission of &amp;gt;108 photons/pulse/sr in 0.1% BW with a critical energy of ∼18 keV was observed by a factor &amp;gt;2 in comparison to the case of no chirp. The role of collective oscillation in enhancing x-ray emission is also validated in the Geant4 simulations.

AXES-2MRS: A new all-sky catalogue of extended X-ray galaxy groups

Context. Understanding baryonic physics at the galaxy-group level is a prerequisite for cosmological studies of the large-scale structure. One poorly understood aspect of galaxy groups is related to the properties of their hot intragroup medium. The well-studied X-ray groups have strong cool cores by which they were selected, so expanding the selection of groups is currently an important avenue in uncovering the diversity within the galaxy group population. Aims. We present a new all-sky catalogue of X-ray-detected groups (AXES-2MRS) based on the identification of large X-ray sources found in the ROSAT All-Sky Survey (RASS) with the Two Micron Redshift Survey (2MRS) Bayesian Group Catalogue. We studied the basic properties of these galaxy groups to gain insights into the effect of different group selections on the properties. Methods. In addition to X-ray luminosity from shallow survey data of RASS, we obtained detailed X-ray properties of the groups by matching the AXES-2MRS catalogue to archival X-ray observations by XMM-Newton and complemented this by adding the published XMM-Newton results on galaxy clusters in our catalogue. We analysed temperature and density to the lowest overdensity accessible by the data, obtaining hydrostatic mass estimates at a uniform overdensity of 10 000 times the critical, M10 000, and comparing them to the velocity dispersions of the groups. We explored the relationship between X-ray and optical properties of AXES-2MRS groups through the σv−LX, σv−kT, kT−LX, σv−M, and c200−LX scaling relations. Results. We find a large spread in the central mass ( M10 000), measured by XMM-Newton, to virial mass (M200), inferred by the velocity dispersion, ratios for galaxy groups. This can either indicate that large non-thermal pressure of galaxy groups affects our X-ray mass measurements or the effect of a diversity of halo concentrations on the X-ray properties of galaxy groups. Previous catalogues based on detecting the peak of the X-ray emission preferentially sample the high-concentration groups. In contrast, our new catalogue uncovered many low-concentration groups, completely revising our understanding of X-ray groups.