This study examined how localization, via binaural cues, can help the tracking of a sound sequence, interleaved with another sound sequence, across time. The ability to track a sequence was investigated using a temporal irregularity detection task. The temporal irregularity was inserted into a regular isotone sequence (target sequence) interleaved with an irregular sequence of same frequency (masker sequence). Performances were at the chance level when there was no interaural difference between the sequences. In experiment 1, large improvements of performances were found using several interaural level (ILD) or time (ITD) differences between the two sequences. Manipulating the masker sequence ILD and maintaining the signal‐to‐noise ratio constant in the best ear (experiment 2) or using a monaural presentation of the sequences (experiment 3), data showed that the effect of ILD could not be explained by a monaural processing (best or bad ear listening). Finally, experiment 4 revealed that the effect of binaural cues on tracking a sound sequence was mainly produced by the perceived localisation differences induced by the interaural differences rather than by the physical differences. These results suggested that binaural cues may influence sound sequence tracking via a spatial attention mechanism.