World's Largest Research Articles

TCT-385 Safety and Efficacy of Coronary Intravascular Lithotripsy With OCT Guidance for Percutaneous Coronary Intervention of Severely Calcified Lesion: Insights From the World's Largest Prospective, Observational Registry (Shock India Registry)

TCT-385 Safety and Efficacy of Coronary Intravascular Lithotripsy With OCT Guidance for Percutaneous Coronary Intervention of Severely Calcified Lesion: Insights From the World's Largest Prospective, Observational Registry (Shock India Registry)

Competition in the Periphytic Algal Community during the Colonization Process: Evidence from the World's Largest Water Diversion Project.

Periphytic algal colonization is common in aquatic systems, but its interspecific competition remains poorly understood. In order to fill the gap, the process of periphytic algal colonization in the Middle Route of the South to North Water Diversion Project was studied. The results showed that the process was divided into three stages: the initial colonization stage (T1, 3-6 days), community formation stage (T2, 12-18 days) and primary succession stage (T3, 24-27 days). In T1, the dominant species were Diatoma vulgaris (Bory), Navicula phyllepta (Kützing) and Fragilaria amphicephaloides (Lange-Bertalot) belonging to Heterokontophyta; these species boasted wide niche widths (NWs), low niche overlap (NO) and low ecological response rates (ERRs). In T2, the dominant species were Diatoma vulgaris, Cymbella affinis (Kützing), Navicula phyllepta, Fragilaria amphicephaloides, Gogorevia exilis (Kützing), Melosira varians (C.Agardh), Phormidium willei (N.L.Gardner) and Cladophora rivularis (Kuntze). These species displayed wider NWs, lower NO, and lower ERRs than those in T1. In T3, the dominant species were Diatoma vulgaris, Cymbella affinis, Navicula phyllepta, Fragilaria amphicephaloides, Achnanthes exigu (Grunow), etc. Among them, Heterokontophyta such as Diatoma vulgaris and Cymbella affinis had a competitive advantage based on NWs and ERRs. Cyanobacteria like Phormidium willei lost their dominant status due to the narrower NW and the increased NO. It could be concluded the interspecific competition became fiercer and shaped the colonization process; this study will be helpful in understanding the colonization of periphytic algal communities.

A Third of Organic Carbon Is Mineral Bound in Permafrost Sediments Exposed by the World's Largest Thaw Slump, Batagay, Siberia

ABSTRACTOrganic carbon (OC) in permafrost interacts with the mineral fraction of soil and sediments, representing < 1% to ~80% of the total OC pool. Quantifying the nature and controls of mineral–OC interactions is therefore crucial for realistic assessments of permafrost‐carbon‐climate feedbacks, especially in ice‐rich regions facing rapid thaw and the development of thermo‐erosion landforms. Here, we analyzed sediment samples from the Batagay megaslump in East Siberia, and we present total element concentrations, mineralogy, and mineral–OC interactions in its different stratigraphic units. Our findings indicate that up to 34 ± 8% of the OC pool interacts with mineral surfaces or elements. Interglacial deposits exhibit enhanced OC–mineral interactions, where OC has undergone greater microbial transformation and has likely low degradability. We provide a first‐order estimate of ~12,000 tons of OC mobilized annually downslope of the headwall (i.e., the approximate mass of 30 large aircrafts), with a maximum of 38% interacting with OC via complexation with metals or associations to poorly crystalline iron oxides. These data imply that over one‐third of the OC exposed by the slump is not readily available for mineralization, potentially leading to prolonged OC residence time in soil and sediments under stable physicochemical conditions.

A Crude Palm Oil Industry Concentration and Influencing Factors: A Case Study of Indonesia as the World's Largest Producer

The Crude Palm Oil (CPO) industry is one of the plantation commodities that has a strategic role in Indonesia's economic development. The number of companies and CPO production is always increasing, but the concentration of the industry that always decreases every year makes it important to analyze the factors that affect the concentration of the CPO industry in Indonesia. The data period used in this study was from 2001 to 2020. In this study, data sources were obtained from the Central Bureau of Statistics (BPS) Indonesia, Word Bank, and UN Comtrade. The data analysis method used is regression analysis of the Error Correction Model (ECM). The results showed that technical efficiency has a negative and significant relationship both in the long and short term to the concentration of the CPO industry. Competitiveness in the long term has a positive and significant relationship, while in the short term it is negative but not significant to the concentration of the Indonesian CPO industry. In the long run, the relationship between RSPO and Indonesia's CPO industry concentration tends to be negative but not significant, while in the short term it shows a significant influence. World CPO prices, both long-term and short-term, provide a positive and significant correlation to the concentration of the Indonesian CPO Industry. Indonesia's CPO exports in the long and short term have a negative and significant effect on the concentration of the Indonesian CPO industry.

The Healthcare Cost of Air Pollution: Evidence from the World's Largest Payment Network

Abstract This paper exploits the universe of credit- and debit-card transactions in China during 2013-2015 and provides the first nationwide analysis of the healthcare cost of PM2.5 for a developing country. We leverage spatial spillovers of PM2.5 from long-range transport to generate exogenous variation in local pollution and employ a flexible distributed lag model to capture semiparametrically the dynamic response of pollution exposure. We find significant impacts of PM2.5 on healthcare spending in both the short and medium terms. A 10 μg/m3 decrease in PM2.5 would reduce annual healthcare spending by over $9.2 billion, about 1.5% of China's annual healthcare expenditure.

Bioaccumulation of metals in Spartina alterniflora salt marshes in the estuary of the World's Largest Choked Lagoon.

Salt marshes are capable of mitigating metal pollution in coastal environments, yet the efficacy of this remediation is contingent upon various environmental factors and the plant species involved. This study investigates the influence of different anthropogenic activities, including industrial, urban, recreational (in an insular area), and dredging operations, on the bioaccumulation of eight metals (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) within Spartina alterniflora Loisel. in the Patos Lagoon estuary, Brazil. The research aims to assess the pattern of metal bioaccumulation and distribution within the plant's leaves, stems, and roots while also examining metal presence in the sediment. Our main findings reveal that S. alterniflora exhibited elevated metal levels in its plant structure directly related with the metal concentrations in the surrounding sediment, which, in turn, is related to the different anthropogenic activities. The industrial area presented the highest metal levels in sediment and plant sections, followed by dredging, insular, and urban areas. This same pattern was mirrored for the bioconcetration factors (BCF), with the BCFs consistently indicating active metal bioaccumulation across all areas and for most of the metals. This provides evidence of the metal bioaccumulation pattern in S. alterniflora, with elevated BCFs in areas affected by activities with a higher degree of impact. Translocation factors (TF) showed varying metal mobility patterns within the plant's below-ground and above-ground sections across the different areas, with only Hg exhibiting consistent translocation across all study areas. Zn was the primary metal contributor in all plant sections, followed by Pb and Cu. It is worth noting that Pb is a non-essential metal for this plant, highlighting the relationship between elevated Pb contributions in the plant sections and the bioaccumulation of this metal within the plant's structure. Overall, this study emphasizes the bioaccumulation capacity of S. alterniflora and elucidate the intrinsic connection between different anthropogenic activities and their impact on the resultant availability and bioaccumulation of metals by this salt marsh plant.

Fishing eDNA in One of the World's Largest Rivers: A Case Study of Cross-Sectional and Depth Profile Sampling in the Yangtze.

The world's largest rivers are home to diverse, endemic, and threatened fish species. However, their sheer sizes make large-scale biomonitoring challenging. While environmental DNA (eDNA) metabarcoding has become an established monitoring approach in smaller freshwater ecosystems, its suitability for large rivers may be challenged by the sheer extent of their cross sections (>1 km wide and tens of meters deep). Here, we sampled fish eDNA from multiple vertical layers and horizontal locations from two cross sections of the lower reach of the Yangtze River in China. Over half of the ASVs (amplicon sequence variants) were detected in only a single combination of the vertical layers and horizontal locations, with ∼7% across all combinations. We estimated the need to sample >100 L of water across the cross-sectional profiles to achieve ASV richness saturation, which translates to ∼60 L of water at the species level. No consistent pattern emerged for prioritizing certain depth and horizontal samples, yet we underline the importance of sampling and integrating different layers and locations simultaneously. Our study highlights the significance of spatially stratified sampling and sampling volumes when using eDNA approaches. Specifically, we developed and tested a scalable and broadly applicable strategy that advances the monitoring and conservation of large rivers.

Aqua Earth: Exploring where Earth got its water.

Aqua Earth: Exploring where Earth got its water.

Twin Research and Human Genetics - News, Views & Comments: Memoirs and Autobiographies by Twins: Research Angles and Human Interest/Twin Research Reviews: Fetal Reduction in Twin Pregnancy; Twins' Personality and Military Service; Growth Restriction in Twins; Advances in Conjoined Twin Separation/Media Reports: Update on Scientist Who Performed Gene Editing on Twins; Twins From 33-Year-Old Embryos; Twins' Outcomes From Dietary Differences;

Twins' memoirs and autobiographies both enlighten and entertain. These works, often overlooked by researchers, may suggest new avenues for investigation, such as nonshared environmental events that propel twins in different directions. Of course, MZ twins' generally parallel experiences and DZ twins generally criss-crossing paths are the bases of fascinating life stories. The following sections examined recent research on fetal reduction in twin pregnancy, twins' personality and military service, growth restriction in twins, and advances in conjoined twin separation. This article closes with reports of a scientist who performed gene editing on twins, a twin conception from 33-year-old embryos, twins' physical outcomes from dietary differences, fraternal twins with the world's largest height difference and the Twin Home Experts who conquer rat infestation in New York.

Wood‐Based Carbon Storage in the Mackenzie River Delta: The World's Largest Mapped Riverine Wood Deposit

AbstractThe Mackenzie River Delta (MRD) has been recognized as an important host of river‐derived wood deposits, and Mackenzie River wood has been found across the Arctic Ocean. Nevertheless, we lack estimates of the amount of carbon stored as wood and its age in the delta, representing a gap in carbon cycle estimates. Here, we use very high‐resolution satellite imagery and deep learning to map wood deposits in the MRD, combining this with field data to measure the stock and age of wood‐based carbon. We find >400,000 individual large wood deposits, collectively storing 3.1 × 1012 g‐C, equating to 2 × 106 g‐C ha−1 across the delta. Sampled wood pieces date from 690 AD to 2015 AD but are mostly young with ∼40% of the wood samples formed after 1955 AD. These estimates represent a minimum bound on an important surficial, potentially reactive, carbon pool compared to other deeper carbon stocks in permafrost zones.

Genomics, Population Divergence, and Historical Demography of the World's Largest and Endangered Butterfly, The Queen Alexandra's Birdwing.

The world's largest butterfly is the microendemic Papua New Guinean Ornithoptera alexandrae. Despite years of conservation efforts to protect its habitat and breed this up-to-28-cm butterfly, this species still figures as endangered in the IUCN Red List and is only known from two allopatric populations occupying a total of only ∼140 km². Here we aim at assembling reference genomes for this species to investigate its genomic diversity, historical demography and determine whether the population is structured, which could provide guidance for conservation programs attempting to (inter)breed the two populations. Using a combination of long and short DNA reads and RNA sequencing, we assembled six reference genomes of the tribe Troidini, with four annotated genomes of O. alexandrae and two genomes of related species Ornithoptera priamus and Troides oblongomaculatus. We estimated the genomic diversity of the three species, and we proposed scenarios for the historical population demography using two polymorphism-based methods taking into account the characteristics of low-polymorphic invertebrates. Indeed, chromosome-scale assemblies reveal very low levels of nuclear heterozygosity across Troidini, which appears to be exceptionally low for O. alexandrae (lower than 0.01%). Demographic analyses demonstrate low and steadily declining Ne throughout O. alexandrae history, with a divergence into two distinct populations about 10,000 years ago. These results suggest that O. alexandrae distribution has been microendemic for a long time. It should also make local conservation programs aware of the genomic divergence of the two populations, which should not be ignored if any attempt is made to cross the two populations.

Comprehensive Radar Mapping of Malaspina Glacier (Sít' Tlein), Alaska—The World's Largest Piedmont Glacier—Reveals Potential for Instability

AbstractMalaspina Glacier, located on the coast of southern Alaska, is the world's largest piedmont glacier. A narrow ice‐cored foreland zone undergoing rapid thermokarst erosion separates the glacier from the relatively warm waters of the Gulf of Alaska. Glacier‐wide thinning rates for Malaspina are greater than 1 m/yr, and previous geophysical investigations indicated that bed elevation exceeds 300 m below sea level in some places. These observations together give rise to the question of glacial stability. To address this question, glacier evolution models are dependent upon detailed observations of Malaspina's subglacial topography. Here, we map 2,000 line‐km of the glacier's bed using airborne radar sounding data collected by NASA's Operation IceBridge. When compared to gridded radar measurements, we find that glaciological models overestimate Malaspina's volume by more than 30%. While we report a mean bed elevation 100 m greater than previous models, we find that Malaspina inhabits a broad basin largely grounded below sea level. Several subglacial channels dissect the glacier's bed: the most prominent of these channels extends at least 35 km up‐glacier from the terminus toward the throat of Seward Glacier. Provided continued foreland erosion, an ice‐ocean connection may promote rapid retreat along these overdeepened subglacial channels, with a global sea‐level rise potential of 1.4 mm.

Optimal Public Transportation Networks: Evidence from the World's Largest Bus Rapid Transit System in Jakarta

Optimal Public Transportation Networks: Evidence from the World's Largest Bus Rapid Transit System in Jakarta

A Critical Analysis of the World's Largest Publicly Funded Health Insurance Program: India's Ayushman Bharat.

Launched in September 2018, the ABPMJAY is the world's largest publicly funded health insurance (PFHI) program with population coverage of 500 million. A systematic review was conducted. A comprehensive literature search was conducted in four databases: PubMed, Web of Science, Scopus, and Google Scholar. The literature search was conducted with the search terms: "Ayushman Bharat OR ABPMJAY OR modicare AND RSBY." The search was set to title and abstract. Gray literature and government websites were also searched for relevant documents. A total of 881 documents were identified (PubMed: 53, Web of Science: 46, Scopus: 97, Google Scholar: 681, government websites: two, and gray literature: two). Fifty-two duplicates were identified. After the elimination of the duplicates, 829 unique documents were identified. These 829 unique citations were then subjected to a review of title and abstract independently by 2 reviewers. Six-hundred and ninety-two articles were rejected after review of title and abstract. One-hundred and thirty-seven articles were screened for full text independently by two reviewers. Sixty-six articles were rejected after review of the full text. Disagreements were resolved by discussion. Seventy-one unique articles were included in the final review. To attain the objective of the study, which is to critically analyze and provide an overview of Ayushman Bharat, a narrative synthesis was performed. Seven themes were identified from the review: (1) health and wellness centers (HWCs); (2) out-of-pocket health expenditure (OOPHE); (3) fraud; (4) upcoding and provision of unnecessary medical care; (5) moving focus away from primary care; (6) coverage; and (7) lop-sided access, exclusion at the periphery, and brain drain. There is very little impact evidence of the ABPMJAY available. The government could plan impact evaluation studies in every state that the ABPMJAY is functional in. Any high-quality feedback generated might enable the National Health Authority, the government body leading and coordinating the ABPMJAY, to take necessary steps operationally and advice the government on strategy. Another concern is that the ABPMJAY PFHI might negatively impact the ongoing process of continuous strengthening and development of the government health-care system at all levels-primary, secondary, and tertiary. Continual recalibration and course corrections on the basis of high-quality feedback might enable ABPMJAY reduce catastrophic OOPHE for 500 million Indians. This is more than 6% of humanity: the largest block of people served by a single PFHI in history.

An Examination of Net-Zero Commitments by the World's Largest Banks

An Examination of Net-Zero Commitments by the World's Largest Banks

Chasing Giants: In Search of the World's Largest Freshwater Fish by Zeb Hogan and Stefan Lovgren (review)

Chasing Giants: In Search of the World's Largest Freshwater Fish by Zeb Hogan and Stefan Lovgren (review)

World's Largest Glaciers: A new list highlights Earth's grandest flows of ice.

World's Largest Glaciers: A new list highlights Earth's grandest flows of ice.

Book Review: Review of Global Christianity: A Guide to the World's Largest Religion from Afghanistan to Zimbabwe

Book Review: Review of Global Christianity: A Guide to the World's Largest Religion from Afghanistan to Zimbabwe

Dissolved Methane in the World's Largest Semi‐Enclosed Estuarine System: The Estuary and Gulf of St. Lawrence (Canada)

AbstractWe report the first water‐column dissolved methane data set from the Estuary and Gulf of St. Lawrence (EGSL). Per surface‐water methane concentration and sea‐to‐air flux, the upper estuary behaved like a typical shallow macrotidal estuary, while the lower estuary and the gulf resembled outer shelf seas and ocean slopes, respectively. The EGSL emitted 166.3 (71.5–214.4) × 106 mol CH4 year−1 to the atmosphere, representing 0.3% (0.1%–0.4%) of the total emission from global estuarine environments. A net production of 11.7 × 107 mol CH4 year−1 was required to sustain this emission. Methane distributions in the upper estuary were dominated by physical mixing, while those in the lower estuary and the gulf bore characteristic subsurface maxima and deep minima shedding light on the methane consumption and production pathways. Elevated but highly variable near‐bottom methane concentrations (10.4–695.3 nmol L−1) transpired over pockmarks on the seabed of the lower estuary, inferring an upward diffusive flux of up to ∼700 mmol CH4 m2 d−1. Hypoxia in the lower estuary bottom water had little influence on methane concentrations. Lab incubations yielded methane cycling rates from a net production of 0.0068 nmol L−1 d−1 to net consumption with turnover times of 33.3–263 days. Methane in the EGSL was isotopically enriched with 13C (δ13CCH4: −40.9‰ to −27.4‰ relative to Peedee Belemnite). This study reveals that the EGSL is a smaller proportional contributor to methane emission from estuarine environments and that complex physical‐biogeochemical interactions control methane cycling and isotopic composition in this vast estuarine system.

WHY INVEST GLOBALLY IN FAMILY FIRMS

Purpose- Family firms have a significant economic role in many countries around the world. Family firms make a significant contribution to World GDP and employ a significant part of the global workforce. The scope of this study covers the top 25 largest and publicly owned family firms announced by Ernst & Young’s 2021 Report for Family Businesses. These 25 family firms generated more than 2 trillion USD and employed 6.5 million in 2021. This empirical study aims to investigate the excess stock returns of family firms over the related country stock market indexes and the risks (betas) for the period between 2002 and 2021. Therefore, this study explores the question of “why invest globally in family firms and whether this investment pays off with higher returns and less risk”. Methodology- The World's Largest Family Companies" list is published every other two years by Ernst & Young and the last issue was published in 2021. The world’s largest family companies list includes both private and publicly owned family firms. This study employs 25 world’s largest family firms after the exclusion of privately held family firms. The monthly stock prices of family firms, related country stock market index values, and global stock market index values are obtained from Refinitiv Eikon (Reuters) database for the period between 2002 and 2021 (20 years). Therefore, a total of 9120 observations are extracted for this empirical study. Eviews-10 is utilized for all econometric analysis. Findings- This study investigates whether an individual or intuitional investor can earn more than the average return of the stock markets by investing in publicly traded family firms meanwhile exposing less risk. The empricial results reveal that Maersek shows 354% (beta of 1.18) excess return over the 20 year period and followed by Hanwha with a 335% (beta of 0.69) excess return. Later, all family firms are grouped based on country of headquartered and 7 country portfolios are formed. The highest excess returns are provided by South Koean portfolio (an excess return of 189% with a beta of 0.83) and it is followed by Indian portfolio (an excess return of 174% with a beta of 1.0). Finaly, a best performer portfolio is formed by the 10 family firms with highest excess returns. This portfolio provides a 131% excess return with a beta of 1.18 over 20-year peirod. Conclusion- The empirical results show that the individual firm returns and portfolio returns of family firms are higher than the returns of the stock market indexes. Those who invest in family businesses get higher returns with less risk. Investments in publicly traded family firms pay off. Keywords: Family firms, global investment, return, risk, stock markets. JEL Codes: G10, G11, G15