SummaryThe conservation and sustainable use of animal genetic resources (AGR) is now recognized as a legitimate activity of public concern in which inter-governmental, governmental, non-governmental and private sectors are involved. Livestock breeds became threatened on a large scale only in the second half of the 20th century. They are now recognized as a significant human heritage resulting from domestication whose loss would deplete the quality of human life. Conservation as a conscious and organized activity is therefore a new item on the public agenda. This paper traces the origin of livestock conservation from the Vision in the 1950s and 1960s through the awakening of the environmental movement with the creation of UNEP in 1972, followed by the development of a Joint Conservation Infrastructure and Programme for animal genetic resources in the 1980s by FAO and UNEP.The paper describes the context, participants, constraints, opposition and activities of building the AGR Conservation Infrastructure and Programme. Although the concept of conservation was opposed by some and there were both financial and political difficulties, an effective institutional infrastructure for conservation was built by FAO by 1990 using UNEP funds. In 1992, the advent of the Convention on BioDiversity offered substantial funding for project activities for the first time through the Global Environmental Facility (GEF). At that point it was desirable to move activities from central planning to the design, funding and operation of local or national conservation projects. “Top-down” institutional control should have been replaced by “Bottom-up” conservation activities. Regrettably this did not happen during the 1990s and, as shown by successive editions of the World Watch List, the number of endangered livestock breeds has continued to increase. Now that the conservation vision is accepted and the institutional infrastructures are in place it is time for a new dynamic by creating and funding specific conservation projects which harness the local human resources of knowledge and enthusiasm.