The article addresses the main trends in the development of world industry within the framework of Industry 4.0 and the new Industry 5.0. The main prerequisites for the emergence of the Industry 5.0 concept are studied, in particular, extensive digitization and the dynamic development of technologies of the fourth industrial revolution, which has led to the certain dehumanization of industry and has increased the interest of the scientific community in the aspects of industrial humanization, human-centeredness of industry, stability, sustainability, and resilience. The main principles and trends of the development of Industry 5.0, the impact of the Covid-19 pandemic, geopolitical crises, and disruptions of the global value chains on the condition and prospects for the development of world industry, new rules and requirements for global product manufacturers, technological innovations, and production trends are studied. The author identifies directions for expanding the concept of Industry 4.0 to include humanization, sustainability, and resilience. The rapid development of new technologies often outpaces the ability of organizations to align their development priorities with it and effectively take advantage of new opportunities, which leads to the need to navigate the changing business environment in time and develop a relevant development strategy. With so many technological changes, changing workforce demands, and social and regulatory priorities, there is a need to define guiding principles to help set the course for the digital industry. Industry 5.0 has become the basis for revising the future of energy, manufacturing, and mobility of supply chains, which rest on the foundations laid by Industry 4.0. The weaknesses of the Industry 4.0 concept, especially in terms of the role of a human in "smart" production and ensuring sustainable development are outlined. Accordingly, the expediency of further research and implementation of the Industry 5.0 concept is substantiated. On the basis of the conducted research on the implementation of Industry 5.0 and the world trends of industrial development, the author justifies the feasibility of reorienting production and business activities to human-centeredness as a new norm, strengthening sustainability, in particular, careful planning of stabilization measures in case of disruption of the global value chains – from factory facilities to network supplier, to transport channels, to regulatory and geopolitical changes, ensuring sustainability with manufacturers rethinking their impact on natural resources in connection with the expansion of the regulatory and legislative framework and investors' attention to reducing carbon emissions and negative impact on the environment.