Working Volume Research Articles

EFFECT OF EFFECTIVE MICROORGANISMS ADDITION ON METHANE PRODUCTION FROM COFFEE HUSKS

Coffee husk is a lignocellulosic material which is abundant and can be used to produce biogas. This study compares the production of biogas produced from coffee husk substrate using cow dung and a mixture of cow dung and effective microorganisms. This experiment was carried out for 30 days in an anaerobic batch reactor with a reactor working volume of 3.6 L at mesophilic temperature. The parameters tested in this study were the lignocellulosic content of coffee husks, total solids (TS), volatile solids (VS), volatile fatty acids (VFA), chemical oxygen demand (COD), and the content of biogas produced from both variables. The lignocellulosic compositions obtained from this study were cellulose 65.90%, hemicellulose 24.95%, lignin 0.21%, pectin 0.42%, protein 0.81%, tannins 1.05%, caffeine 0.09%, and polyphenols. The values of Total Solids and Volatile Solids for the two variables are K-KS of 16.78% and 33.98% and K-KSEM of 24.87% and 48.42%, respectively. The total VFA for the two variables is 2.06% (v/v) for K-KS and 2.36% (v/v) for K-KSEM. The COD values for the K-KS and K-KSEM variables were 78.05% and 81.42%, respectively. The composition of biogas for K-KS is CH4 12.35%, CO2 21.68%, and H2 0.32%, while for K-KSEM it is CH4 19.64%, CO2 2.82%, and H2 0.35 %. The methane yields for the two variables, K-KS and K-KSEM, were 0.76 Nm3/kgCODremoval and 1.43 Nm3/kgCODremoval, respectively.Key words: anaerobic digestion, cow dung, rumen fluid, effective microorganism (EM), methane

Scale-up and energy estimations of single- and two-stage vinasse anaerobic digestion systems for hydrogen and methane production

This study evaluated the full-scale vinasse anaerobic digestion for industrial application. Twelve scenarios were simulated, considering single (methanogenic reactor) and two-stage systems (acidogenic + methanogenic reactors), raw and concentrated vinasse, thermophilic and mesophilic conditions for methanogenesis and usage of acidogenic or methanogenic reactor effluent to dilute vinasse. A single-stage anaerobic digestion system of 17,433 m³ necessary to treat all the raw vinasse produced by a mill with a grinding capacity of 3.3 million tons of sugarcane per season can generate a power of 11.1 MW with an energy yield of 4.6 MJ/kg CODremoved. Two-stage system scenarios where vinasse was diluted with acidogenic reactor effluent had worse energetic recoveries than the single-stage system. Nonetheless, the usage of the methanogenic reactor effluent to dilute vinasse and its own influent in a two-stage system achieved an energetic recovery at least 34% higher than that of the single-stage system. In the best two-stage scenario, the total working volume was 19,666 m³, combining thermophilic acidogenic reactors and mesophilic methanogenic reactors, with an energy yield of 7.0 MJ/kg CODremoved. The different combinations of temperatures allow for a safer and more economic operation. The proposed novel industrial configuration can be divided into two parallel acidogenic reactors of 1,800 m³ each, and those reactors are in series with eight parallel methanogenic reactors of 2,828 m³ each. The electricity produced by the full-scale system can supply an energy demand of 24 thousand inhabitants per harvest season (9.7 kWh per ton of sugarcane). This study presents a novel discussion for sugarcane industry decision makers, such as plant managers, process and project engineers, providing a trade-off between highest energy production, optimal COD removal and lowest reactor volume (CAPEX investment) that better fits their needs.

Continuous electrocoagulation of Chlorella vulgaris in a novel channel-flow reactor: A pilot-scale harvesting study

The most frequently used method to harvest microalgae on an industrial scale is centrifugation, although this has very high energy costs. To reduce these costs, a continuous electrocoagulation process for harvesting Chlorella vulgaris was developed and tested using a pilot-scale 111 L working volume device consisting of an electrolyser with iron electrodes, aggregation channel and lamellar settler. The flow rate of the microalgal suspension through the device was 240 L/h. When using controlled cultivation and subsequent electrocoagulation, a high harvesting efficiency (above 85%), a low Fe contamination in the harvested biomass (<4 mg Fe/g dry biomass, a harvested biomass complied with legislative requirements for food) and significant energy savings were achieved. When comparing electrocoagulation and subsequent centrifugation with the use of centrifugation alone, energy savings were 80 % for a biomass harvesting concentration of 0.23 g/L. Electrocoagulation was thus proven to be a feasible pre-concentration method for harvesting microalgae.

Impact of dissolved oxygen on hospital wastewater quality treated by SBBR in Basrah city, Iraq

The hospitals close to the residences can make problems for the environment as a consequence of sewage drained into the water stream. Sequencing batch biofilm reactor (SBBR) offers advantages for treating sewage; such as simple operation, flexible process, and cost-effective. The laboratory bench-scale experiments were carried out treating hospital wastewater (HWW) of one of Basrah hospital city by a fabricated SBBR reactor of 26 l working volume. The hospital wastewater has the following characteristics (average values): pH 7.3, BOD equal to 280 mg·l–1, COD equal to 550 mg·l–1, total phosphorus (TP) equal to 6.4 mg·l–1, ammonia (NH3-N) equal to 44 mg·l–1 and total suspended solid (TSS) equal to 272 mg·l–1. This research aims to estimate the performance of the SBBR system for treating hospital wastewater to enhance different effluent parameters such as COD, total nitrogen (TN), ammonia, and total phosphorous (TP) with various dissolved oxygen (DO) with range of 2.15–6.55 mg·l–1, the best DO values give these removal efficiencies for COD equal to 84.55%, NH3-N equal to 65.91% and TN between 78 and 18% for DO equal to 3.67 mg·l–1, while TP removal efficiency was 79.70% for DO equal to 6.55 mg·l–1. By comparison of the SBBR effluent with international standards for effluent sewage, it noticed COD concentration 85 mg·l–1, TN 12 mg·l–1 and TP 1.3 mg·l–1 met all standards (European, WHO, and China), while NH3-N 15 mg·l–1 was outside WHO and European standards, while satisfies only Chinese standard.

Dynamic characteristics modeling of rotary platform installed on board of a small spacecraft

The paper analyzes the capabilities of an automatic rotary platform of the "Flyuger" type to reduce micro-accelerations in a protected area when it is installed on a small spacecraft of the "Aist-2" type. The micro-accelerations field of the working volume of scientific equipment of the "Growth installation" type has been modeled. The comparison with flight test data is made. The results of the work can be used in the design of small technological spacecraft.

Пуск дизельного двигателя 1Ч9,5/8,0 путем принудительной подачи предварительно разогретого воздушного заряда

The use of small-sized air-cooled diesel engines as part of mobile units for operation in the harsh climatic conditions of the Arctic is a rather difficult task. As the ambient temperature decreases, the temperature at the compression stroke end, which is necessary for the appearance of the first flashes in the diesel cylinder, decreases significantly. At the ambient temperature of minus 60°C, start of a diesel engine becomes impossible. The stage of the appearance of the first flashes is very important for the subsequent spin-up of the crankshaft and the onset of a diesel engine independent operation on fuel without the involvement of auxiliary starting devices. The article proposes a method and device for increasing the temperature in the combustion chamber at the compression stroke end. The results of a diesel engine start at various negative ambient temperatures are given. The regularities of the dynamics of starting a diesel engine 1Ch9.5/8.0 and the dependence of the crankshaft speed during start-up on the ambient temperature is established. The rational range of intake air temperature required for the diesel engine start-up by the proposed method at an ambient temperature from minus 50 to minus 60°C is determined. The proposed method and device can be applied in similar diesel engines with a smaller working volume.

Electro-coagulation of Bio-treated Pharmaceutical Wastewater for RO Pretreatment

Background: The advanced wastewater and water treatment by Reverse Osmosis (RO) system have almost become a common treatment option in industries. However, achieving a consistent RO feed water quality and the rigor of RO pre-treatment pose a big challenge for water treatment specialists. Due to the RO critical limiting feed parameters (Silica, Turbidity, BOD, and Total hardness) and the inadequate consideration of the limiting feed parameters in the recycling plant design, the Reverse Plant likely fails due to scaling of membrane and poor productivity. This calls for judicious consideration of an appropriate pre-treatment technology in line with the feed water quality.&#x0D; Objective: The objective of the work was to study the electro-coagulation treatment of pharmaceutical wastewater with reference to critical RO feed parameters.&#x0D; Materials and Methods: In this paper, the Electro-coagulation (EC) treatment of Bio-treated pharmaceutical wastewater was explored as a Pre-treatment for the RO system. In the EC reactor of 1m3 working volume, bipolar sacrificial Iron electrodes were used, and RO Critical parameters were examined post electro-coagulation treatment.&#x0D; Results: Among the 14 RO critical parameters that was investigated, five parameters namely Aluminium as Al, Iron as Fe, Turbidity, Zinc as Zn, and Silica as SiO2 have registered a reduction range of 80 to 96 %, in the RO feed water after electro-coagulation. Four other parameters like Manganese as Mn, BOD, Phosphate as P, and Magnesium as Mg have shown a reduction range of 50 to 80%.&#x0D; This enables the plant to be operated at higher efficiency with increased RO recovery. The test parameters before and after the study were subjected to regression analysis and were found to have a statistical significance of one and P&lt;0.01.&#x0D; Conclusion: EC pre-treatment is applicable for all types of RO (Disc &amp; plate, conventional wound) membranes and enhances the life of the membrane by reducing membrane fouling, maintenance, chemical cleaning, and overall treatment cost.

Accuracy improvement of linear stages using on-machine geometric error measurement system and error transformation model.

In order to improve the accuracy of linear stages, a compact, portable and easy installation of a six-degree-of-freedom (6DOF) geometric error measurement system, in which two mirrors with special position and orientation are innovatively regarded as the sensitive elements of the roll error, is proposed. A set of combined focus lenses is integrated into the 6DOF measurement system to improve the resolution of the roll error. The accuracy of a linear stage is evaluated by the positional errors at the functional point, which is located at the working volume of a linear stage. An error transformation model based on the Abbe principle and the Bryan principle is established to estimate the positional errors at the functional point according to those at the measurement point. A series of experiments are carried out to verify the capable of the designed system and the effectiveness of the established model.

Simultaneous Heterotrophic Nitrification and Aerobic Denitrification of Water after Sludge Dewatering in Two Sequential Moving Bed Biofilm Reactors (MBBR).

Water after sludge dewatering, also known as reject water from anaerobic digestion, is recycled back to the main wastewater treatment inlet in the wastewater treatment plant Porsgrunn, Norway, causing periodic process disturbance due to high ammonium of 568 (±76.7) mg/L and total chemical oxygen demand (tCOD) of 2825 (±526) mg/L. The main aim of this study was the simultaneous treatment of reject water ammonium and COD using two pilot-scale sequential moving bed biofilm reactors (MBBR) implemented in the main wastewater treatment stream. The two pilot MBBRs each had a working volume of 67.4 L. The biofilm carriers used had a protected surface area of 650 m2/m3 with a 60% filling ratio. The results indicate that the combined ammonia removal efficiency (ARE) in both reactors was 65.9%, while the nitrite accumulation rate (NAR) and nitrate production rate (NPR) were 80.2 and 19.8%, respectively. Over 28% of the reject water’s tCOD was removed in both reactors. The heterotrophic nitrification and oxygen tolerant aerobic denitrification were the key biological mechanisms found for the ammonium removal in both reactors. The dominant bacterial family in both reactors was Alcaligenaceae, capable of simultaneous heterotrophic nitrification and denitrification. Moreover, microbial families that were found with equal potential for application of simultaneous heterotrophic nitrification and aerobic denitrification including Cloacamonaceae, Alcaligenaceae, Comamonadaceae, Microbacteriaceae, and Anaerolinaceae.

Statistical experimental designs to optimize the transient transfection of HEK 293T cells and determine a transfer criterion from adherent cells to larger-scale cell suspension cultures

The transient transfection of mammalian cells is a rapid and versatile platform for the manufacture of recombinant proteins, but industrial processes depend on reliable scalability and efficient conversion from adherent to suspension cell cultures. Here we describe the optimized transfection of HEK 293T cells in both culture formats. DMEM was the best transfection medium for adherent HEK 293T cells, so we determined the kinetics of linear polyethyleneimine (LPEI) polyplex formation with plasmid DNA (pDNA) and subsequent cellular uptake. Statistical experimental designs revealed optimal transfection efficiency using 0.7 pg pDNA and 4.5 pg LPEI per cell. We used the amount of pDNA and LPEI per cell as the transfer criterion for HEK 293T/17 SF cell suspension cultures in FreeStyle 293 medium and confirmed optimal transfection at 1.1 pg pDNA and 6.6 pg LPEI per cell. We observed a strong correlation between polyplex size, transfection efficiency and post-transfection cell viability. Suspension cell transfection could be scaled to a 100-mL working volume without loss of efficiency. We conclude that pg pDNA and pg LPEI per cell is a suitable transfer criterion allowing the optimization of transient transfection using statistical experimental designs, thus minimizing the amount of pDNA and LPEI used without sacrificing transfection efficiency.

Secretory production of an engineered cutinase in Bacillus subtilis for efficient biocatalytic depolymerization of polyethylene terephthalate.

Polyethylene terephthalate (PET) waste has caused serious environmental pollution. Recently, PET depolymerization by enzymes with PET-depolymerizing activity has received attention as a solution to recycle PET. An engineered variant of leaf-branch compost cutinase (293 amino acid), ICCG (Phe243Ile/Asp238Cys/Ser283Cys/Tyr127Gly), showed excellent depolymerizing activity toward PET at 72°C, which was the highest depolymerizing activity and thermo-stability ever reported in previous works. However, this enzyme was only produced by heterologous expression in the cytoplasm of Escherichia coli, which requires complex separation and purification steps. To simplify the purification steps of ICCG, we developed a secretory production system using Bacillus subtilis and its 174 types of N-terminal signal peptides. The recombinant strain expressing ICCG with the signal peptide of serine protease secreted the highest amount (9.4 U/mL) of ICCG. We improved the production of ICCG up to 22.6 U/mL (85μg/mL) by performing batch fermentation of the selected strain in 2 L working volume using a 5-L fermenter, and prepared the crude ICCG solution by concentrating the culture supernatant. The recombinant ICCG successfully depolymerized a PET film with 37% crystallinity at 37°C and 70°C. In this study, we developed a secretory production system of the engineered cutinase with PET-depolymerizing activity to obtain high amounts of the enzyme by a relatively simple purification method. This system will contribute to the recycling of PET waste via a more efficient and environmentally friendly method based on enzymes with PET-depolymerizing activity.

Torulaspora quercuum shows great potential for bioethanol production from macroalgal hydrolysate

Yeast fermenting galactose (Gal) to ethanol are key to develop bioethanol production from galactan-rich red algal feedstock. To improve Gal-based bioethanol production, the potential of non-Saccharomyces yeast was investigated with screening Gal-fermenting yeast from environment in this study. Isolates, Torulaspora quercuum strains KRT82 and KRT85 were successfully effectively produced 54.77 ± 2.18 and 59.92 ± 2.18 g L−1 ethanol, respectively, from 200 g L−1 Gal as the carbon source in modified yeast–malt broth. The ethanol yield reached nearly corresponding to the theoretical yield. The isolates produced 8–10 g L−1 ethanol from Gelidiaceae hydrolysate containing approximately 20 g L−1 Gal and 10–13 g L−1 glucose, with an ethanol yield of 54%–57%. The cells flocculated. During repeated batch fermentation, the ethanol yield were reached to 38 g L−1-working volume for 39 h, and the productivity of ethanol reached 0.98 g L−1 working volume h−1.

Effect of Hydraulic Retention Time on the Performance of a Compact Moving Bed Biofilm Reactor for Effluent Polishing of Treated Sewage

Treated effluent from a wastewater treatment plant can be further reused as a water resource for a water supply treatment plant. In this case, the treated sewage gathered in the study of the Class V National Water Quality Standard (NWQS) of Malaysia would be treated for use as a water resource for a water treatment plant. In a moving bed biofilm reactor (MBBR) with a 500-L working volume, organic pollutants, undesirable nutrients, and bacteria were removed without disinfectant. At 24-h hydraulic retention time (HRT), the maximum removal efficiency of 5-day biological oxygen demand, ammonia–nitrogen (NH3-N), and total phosphorus were 71%, 48%, and 12%, respectively. The biofilm thickness, which was captured using scanning electron microscopy, increased from 102.6 μm (24-h HRT) to 297.1 μm (2-h HRT). A metagenomic analysis using 16S rRNA showed an abundance of anaerobic bacteria, especially from the Proteobacteria phylum, which made up almost 53% of the total microbes. MBBR operated at 24-h HRT could improve effluent quality, as its characteristics fell into Class IIA of the NWQS of Malaysia, with the exception of the NH3-N content, which indicated that the effluent needed conventional treatment prior to being reused as potable water.

A Float Meter Based System for Self-Regulated Discharging and Feeding in a Laboratory Semi-CSTR for Anaerobic Digestion of Chicken Litter

HighlightsA float meter based system (FMBS) was designed for self-regulated discharging and feeding in an anaerobic semi-CSTR.The accuracy and feasibility of the FMBS were determined for anaerobic digestion of chicken litter.The FMBS had the advantages of much lower cost and better full working volume control than a digital accurate pump system (DAPS).Abstract. Given the rapidly rising costs in building lab-scale reactors, efforts are needed to examine innovative designs of reactor systems to reduce the expenses of scientific research. In this study, a float meter based system (FMBS) was designed for self-regulated discharging and feeding to operate a semi-CSTR for anaerobic digestion of chicken litter (CL) with wheat straw (WS). The FMBS functioned properly in following a feeding, reaction (stirring), settling, and discharging cycle based on the hydraulic retention time (HRT). However, clogging in the feeding or discharging lines of the reactor might occur for co-digestion of CL and WS with high TS content (C/N = 20, TS = 6%). Compared with a digital accurate pump system (DAPS), the FMBS showed the advantages of low cost ($182 &amp;lt;&amp;lt; $6000) and better control of the full working volume. The longest HRT that could be achieved in this study with an exchange liquid volume of 2 L in each operating cycle was 100.7 h. In all, the FMBS design could serve as a low-cost option for designing lab-scale, semi-CSTR for anaerobic digestion as well as other reactor configurations. Keywords: Anaerobic semi-CSTR, Feeding and discharging, Float meter, Self-regulated.

Підвищення подачі шестеренних насосів засобів транспорту та сільськогосподарської техніки

The purpose of this publication is to develop a mathematical model of the gear pump, which will develop a method for calculating the gearing of the pump with increased specific feed. One of the promising areas for further development of the gear pump is to increase its supply. And if the design of the pump with high flow is solved by increasing its dimensions - is an engineering problem, then increase the flow while maintaining its dimensions, ie increase the specific flow and specific power of the pump is a rather difficult scientific problem. Using the dimensionless GCUR - it is possible to estimate easily advantages of gearing of any two pairs of gear wheels on giving.From the dependences we see that the GCUR does not depend on the gearing module, which is an unexpected result, because it is known that the module plays a major role in increasing the supply of the pump. It is known that the gearing module plays the role of a scale factor, that is, with the growth of the module increases the RON, but the overall dimensions and weight of the pump increase. Therefore, increasing the RON by increasing the gearing module has its limitations, moreover, this method of increasing the feed is not able to increase the specific feed, and therefore does not increase the technical level of the pump on this parameter The results of the above studies, as well as production experience, show that the most significant effect on the volume utilization of the gear rings has the number of teeth of the pump gears. At the same time, reducing the number of teeth helps to increase the utilization rate of the gear rings. The minimum number of gear teeth z = 8 currently in use in the industry is teeth, which is the classic number of teeth of pump gears with an average value of working volume –q = 32…50 см3.

Effects of Aeration Rates and Patterns on Shortcut Nitrification and Denitrification

The effects of aeration rates and aeration patterns on the oxidation of ammonia-nitrogen into nitrite were investigated. The influent high ammonia-nitrogen synthetic wastewater resembled to those of the catalytic process of the petrochemical refinery. The method involved the biological shortcut nitrification and denitrification lab-scale’s sequencing batch reactor (SBR) process based on intermittent aerations and aeration patterns. All the operations were carried out in a 20 L working volume SBR bioreactor, and the influent synthetic wastewater’s concentration was always 1000 mg/L ammonia-nitrogen NH4-N concentration at a C/N (carbon/nitrogen) ratio of 2.5:1. Effective shortcut nitrification to nitrite was registered at 1.1 mg-O2/L (i.e. 9 L-air/min) with 99.1% nitrification efficiency, 99.0% nitritation rate and 2.6 mg-NO3--N/L nitrate concentration. The best results with 99.3% nitrification efficiency were recorded when operating at 1.4 mg-O2/L (i.e. 12 L-air/min). According to these experiments, it results that the nitrite accumulation rate was related to aeration rate and cycle’s duration. However, at 1.7 mg-O2/L (i.e. 15 L-air/min), the system was limited by an increase in nitrate concentration with more than 5 mg/L which could be a point of reverse to conventional nitrification. The best total nitrogen (TN) removal was about 71.5%.

Thermodynamic Calculation of a Rotary Engine with External Heat Supply Based on the Ideal Rallis Cycle

Abstract The design and kinematic scheme of the operation of a rotary external combustion engine with offset shafts have been developed. Expressions are obtained that make it possible to calculate the values of the increasing and decreasing functions of the working volume of the hot and cold cavities with a change in the angle of rotation of the rotor. An expression is obtained for calculating the compression ratio in the cold cavity of a rotary heat engine with an external heat supply. An expression has been determined that makes it possible to calculate the total torque of a rotary external combustion engine. A comparative analysis of the torque values of a rotary heat engine with an external heat supply and a Wankel engine is carried out. An assessment of the efficiency of an external combustion engine with offset shafts is carried out. Based on the thermodynamic calculations using ideal Erickson and Rallis cycles for a rotary external combustion engine, the processes occurring inside the hot and cold cavities of a heat engine are described. The thermodynamic condition parameters at the characteristic points of the cycle are determined and expressions are obtained that determine the thermal efficiency of the ideal Erickson and Rallis cycles in relation to the considered external combustion engine. A method for calculating the ideal cycle for an external combustion engine with offset shafts is presented.

Financial Implication of COVID-19: A Story of Malaysian Dental Practitioner

Coronavirus disease 2019 (COVID-19) has caused series of lockdown in Malaysia which led to the significant financial impact to dental practitioner in Malaysia. Objectives: The aim of this study is to investigate factors affecting dental practice and its implication to financial situation during the pandemic in Malaysia. Methods: Registered Malaysian dental practitioners were invited to participate in online questionnaire via google form. Descriptive and Pearson’s chi-square test analysis were conducted (p&lt;0.05). Results: 468 of dental practitioners had responded to our survey. More than three-quarter of dental practitioners worked in government sectors while almost a quarter worked in private sectors. 49.2% of respondents opened for emergency cases only during movement control order (MCO), 42.1 % of them limit for dental emergency, appointment-based cases and non-aerosol generated procedure during Conditional MCO and 62.5% operated as usual following a strict standard operating procedure during Recovery MCO. More than three quarter of private dental practitioners indicated that pandemic affected their daily monetary income (p&lt;0.001) while most of them had to spend other source of income (p=0.004). All working sectors dictated that the working volume and number of patients had statistically decrease (p&lt;0.05). Conclusion: COVID-19 pandemic had an impact on the practice of dentistry and financial position especially for private dental practitioners. Major government assistance is important to reduce the burden of dental practitioner and preserving their future practice.

A Simulation Analysis of an Influenza Vaccine Production Plant in Areas of High Humanitarian Flow. A Preliminary Study for the Region of Norte de Santander (Colombia)

The production of vaccines of biological origin presents a tremendous challenge for researchers. In this context, animal cell cultures are an excellent alternative for the isolation and production of biologicals against several viruses, since they have an affinity with viruses and a great capacity for their replicability. Different variables have been studied to know the system’s ideal parameters, allowing it to obtain profitable and competitive products. Consequently, this work focuses its efforts on evaluating an alternative for producing an anti-influenza biological from MDCK cells using SuperPro Designer v8.0 software. The process uses the DMEN culture medium supplemented with nutrients as raw material for cell development; the MDCK cells were obtained from a potential scale-up with a final working volume of 500 L, four days of residence time, inoculum volume of 10%, and continuous working mode with up to a total of 7400 h/Yr of work. The scheme has the necessary equipment for the vaccine’s production, infection, and manufacture with yields of up to 416,698 units/h. In addition, it was estimated to be economically viable to produce recombinant vaccines with competitive prices of up to 0.31 USD/unit.

Clinical Interpretation of Working Volume and Weight Support in Upper Limb Robotic Neurorehabilitation after Stroke

In the past two decades, many studies reported the efficacy of upper limb robotic rehabilitation in patients after stroke, also in its chronic phase. Among the possible advantages of robotic therapy over conventional therapy are the objective measurements of kinematic and kinetic parameters during therapy, such as the spatial volume covered by the patient’s upper limb and the weight support provided by the robot. However, the clinical meaning and the usability of this information is still questioned. Forty patients with chronic stroke were enrolled in this study and assessed at the beginning of upper limb robotic therapy (Armeo® Power) and after two weeks (ten sessions) of therapy by recording the working volume and weight support provided by the robot and by administering six clinical scales to assess upper limb mobility, strength, spasticity, pain, neurological deficits, and independency. At baseline, the working volume significantly correlated with spasticity, whereas weight support significantly correlated with upper limb strength, pain, spasticity, and neurological deficits. After two weeks of robotic rehabilitation, all the clinical scores as well as the two parameters improved. However, the percentage changes in the working volume and weight support did not significantly correlate with any of the changes in clinical scores. These results suggest caution in using the robotic parameters as outcome measures because they could follow the general improvement of the patient, but complex relationships with clinical features are possible. Robotic parameters should be analyzed in combination with the clinical scores or other objective measures because they may be informative about therapy progression, and there is a need to combine their clinical, neuroscientific, and biomechanical results to avoid misleading interpretations.