The current study examined personal and environmental factors that placed 167 U.S. journalists from diverse media organizations at risk for post-traumatic stress disorder (PTSD) after covering work-related traumatic stories. These factors included exposure to traumatic stressors in their personal lives, work-related traumatic stressors, and general organizational stressors. Further, personality attributes and coping styles associated with risk and resiliency were examined. Regression analyses identified avoidant emotional coping, higher levels of perceived organizational stressors, intensity of exposure to work-related traumatic stressors, and personal trauma history as statistically significant risk factors for PTSD. The results provide empirical support for the negative impact of organizational stressors and avoidant emotional coping on journalists covering trauma-related stories. Understanding the organizational climate journalists are working in, as well as the manner in which journalists manage work-related stressors, is important in the development of a more comprehensive model of who may develop work-related PTSD symptoms. Opportunities for news organizations to reduce PTSD risk among journalists are discussed.