Over 500 oriented samples were collected from a homoclinal sequence of Lower and Middle Cambrian terrigenous and carbonate miogeoclinal strata in the Desert Range, Nevada. Extensive thermal demagnetization was successful in isolating similar characteristic magnetization directions in red‐purple mudstones of the Wood Canyon Formation (Lower(?) and Lower Cambrian) and in gray limestones of the Carrara and Bonanza King Formations (Lower and Middle Cambrian). Lithologic and magnetic evidence suggest that these magnetizations were acquired penecontemporaneously with deposition. The similarity of the characteristic magnetization directions in these strata implies that little apparent polar wander occurred with respect to North America from early Early through middle Middle Cambrian time. The divergence of these directions from those from the partly coeval Tapeats Sandstone of the Colorado Plateau probably resulted from a net 36° clockwise rotation of the Desert Range section about a vertical axis. This rotation is probably due to mid‐Tertiary oroflexural bending but may in part have been caused by Mesozoic thrusting. The polarity of the geomagnetic field in early Middle Cambrian time appears to have been continuously reversed. Stratigraphic intervals of mixed polarity, possibly correlative with those found in the Tapeats, may be present in the Lower Cambrian Zabriskie Quartzite.