Wisconsin Breast Cancer Dataset Research Articles

Comparative analysis of machine learning models for breast cancer prediction and diagnosis: a dual-dataset approach

<p>Breast cancer is ranked as a significant cause of mortality among females globally. Its complex nature poses principal challenges for physicians and researchers for rapid diagnosis and prognosis. Hence, machine learning algorithms are employed to forecast and identify diseases. This study discusses the comparative analysis of seven machine learning models, e.g., logistic regression (LR), support vector machine (SVM), k-nearest neighbor classifier (KNN), decision tree classifier (DT), random forest classifier (RF), Naïve Bayes (NB), and artificial neural network (ANN) to predict breast cancer using Wisconsin breast cancer and breast cancer datasets. In the Wisconsin breast cancer dataset, KNN depicted 99% accuracy, followed by RF (98%), SVM (96%), NB (96%), LR (96%), ANN (93%), and DT (92%). On the contrary, in the breast cancer (BC) dataset, the highest accuracy was achieved by LR at 83%, and the lowest was achieved by DT (65%), which depicted that the numeric dataset WBC has better accuracy than the breast cancer dataset.</p>

Breast Cancer Disease Prediction Using Random Forest Regression and Gradient Boosting Regression

The current research endeavors to evaluate the efficacy of regression-based machine learning algorithms through an assessment of their performance using diverse metrics. The focus of our study involves the implementation of the breast cancer Wisconsin (Diagnostic) dataset, employing both the random forest and gradient-boosting regression algorithms. In our comprehensive performance analysis, we utilized key metrics such as Mean Squared Error (MSE), R-squared, Mean Absolute Error (MAE), and Coefficient of Determination (COD), supplemented by additional metrics. The evaluation aimed to gauge the algorithms' accuracy and predictive capabilities. Notably, for continuous target variables, the gradient-boosting regression model emerged as particularly noteworthy in terms of performance when compared to other models. The gradient-boosting regression model exhibited remarkable results, highlighting its superiority in handling the breast cancer dataset. The model achieved an impressively low MSE value of 0.05, indicating minimal prediction errors. Furthermore, the R-squared value of 0.89 highlighted the model's ability to explain the variance in the data, affirming its robust predictive power. The Mean Absolute Error (MAE) of 0.14 reinforced the model's accuracy in predicting continuous outcomes. Beyond these core metrics, the study incorporated additional measures to provide a comprehensive understanding of the algorithms' performance. The findings underscore the potential of gradient-boosting regression in enhancing predictive accuracy for datasets with continuous target variables, particularly evident in the context of breast cancer diagnosis. This research contributes valuable insights to the ongoing exploration of machine learning algorithms, providing a basis for informed decision-making in medical and predictive analytics domains.

Feature Selection using Extra Trees for Breast Cancer Prediction

Breast cancer is a disease that seriously threatens women's health. It is considering a common death cause in women. Machine learning has made significant progress in recent years to improve the effectiveness of early diagnosis of various diseases. Accurate predication and detection help decrease the death rate of breast cancer. This paper aims to predict breast cancer using several machine-learning techniques. The idea is to lower the number of features in the Wisconsin Breast Cancer Dataset (WCDB) and use it for prediction. The study used the extra trees method for feature selection and Random forest, Logistic regression, and Support Vector Machine (SVM) for testing the dataset. According to the results, SVM achieved the best performance among the other models with 98% accuracy. The proposed method in this study proved its effectiveness in breast cancer prediction.

Integrating hybrid transfer learning with attention-enhanced deep learning models to improve breast cancer diagnosis.

Cancer, with its high fatality rate, instills fear in countless individuals worldwide. However, effective diagnosis and treatment can often lead to a successful cure. Computer-assisted diagnostics, especially in the context of deep learning, have become prominent methods for primary screening of various diseases, including cancer. Deep learning, an artificial intelligence technique that enables computers to reason like humans, has recently gained significant attention. This study focuses on training a deep neural network to predict breast cancer. With the advancements in medical imaging technologies such as X-ray, magnetic resonance imaging (MRI), and computed tomography (CT) scans, deep learning has become essential in analyzing and managing extensive image datasets. The objective of this research is to propose a deep-learning model for the identification and categorization of breast tumors. The system's performance was evaluated using the breast cancer identification (BreakHis) classification datasets from the Kaggle repository and the Wisconsin Breast Cancer Dataset (WBC) from the UCI repository. The study's findings demonstrated an impressive accuracy rate of 100%, surpassing other state-of-the-art approaches. The suggested model was thoroughly evaluated using F1-score, recall, precision, and accuracy metrics on the WBC dataset. Training, validation, and testing were conducted using pre-processed datasets, leading to remarkable results of 99.8% recall rate, 99.06% F1-score, and 100% accuracy rate on the BreakHis dataset. Similarly, on the WBC dataset, the model achieved a 99% accuracy rate, a 98.7% recall rate, and a 99.03% F1-score. These outcomes highlight the potential of deep learning models in accurately diagnosing breast cancer. Based on our research, it is evident that the proposed system outperforms existing approaches in this field.

Breast Cancer Classification using XGBoost

Breast cancer continues to be one of the foremost illnesses that results in the deaths of numerous women each year. Among the female population, approximately 8% are diagnosed with Breast cancer (BC), following Lung Cancer. The alarming rise in fatality rates can be attributed to breast cancer being the second leading cause. Breast cancer manifests through genetic transformations, persistent pain, alterations in size, color (redness), and texture of the breast's skin. Pathologists rely on the classification of breast cancer to identify a specific and targeted prognosis, achieved through binary classification (normal/abnormal). Artificial intelligence (AI) has been employed to diagnose breast tumors swiftly and accurately at an early stage. This study employs the Extreme Gradient Boosting (XGBoost) machine learning technique for the detection and analysis of breast cancer. XGBoost provides an accuracy of 94.74% and recall of 95.24% on Wisconsin breast cancer Wisconsin (diagnostic) dataset.

Breast Cancer Prediction Based on Multiple Machine Learning Algorithms.

The incidence of breast cancer has steadily risen over the years owing to changes in lifestyle and environment. Presently, breast cancer is one of the primary causes of cancer-related deaths among women, making it a crucial global public health concern. Thus, the creation of an automated diagnostic system for breast cancer bears great importance in the medical community. This study analyses the Wisconsin breast cancer dataset and develops a machine learning algorithm for accurately classifying breast cancer as benign or malignant. Our research is a retrospective study, and the main purpose is to develop a high-precision classification algorithm for benign and malignant breast cancer. To achieve this, we first preprocessed the dataset using standard techniques such as feature scaling and handling missing values. We assessed the normality of the data distribution initially, after which we opted for Spearman correlation analysis to examine the relationship between the feature subset data and the labeled data, considering the normality test results. We subsequently employed the Wilcoxon rank sum test to investigate the dissimilarities in distribution among various breast cancer feature data. We constructed the feature subset based on statistical results and trained 7 machine learning algorithms, specifically the decision tree, stochastic gradient descent algorithm, random forest algorithm, support vector machine algorithm, logistics algorithm, and AdaBoost algorithm. The results of the evaluation indicated that the AdaBoost-Logistic algorithm achieved an accuracy of 99.12%, outperforming the other 6 algorithms and previous techniques. The constructed AdaBoost-Logistic algorithm exhibits significant precision with the Wisconsin breast cancer dataset, achieving commendable classification performance for both benign and malignant breast cancer cases.

Clinical Dataset Classification Using Feature Ranking And Satin Bower Bird Optimized SVMs

Abstract A clinical decision support system is a computer-based system that is designed to assist healthcare providers with clinical decision-making by analyzing electronic health records and other healthcare information systems to provide real-time support to clinicians at the point of care. A novel classification framework for clinical datasets in which the relevant features are selected by ranking them based on Fisher’s Score and a wrapper-based Satin Bower Bird Optimization algorithm with the combination of accuracy, G-mean and F-Score measured by support vector machine (SVM) as the fitness function is proposed. The classification is performed using an SVM classifier in which the hyperparameters of the SVM classifier are optimized using the Satin Bower Bird Optimization that improves the classification performance. In the context of statistical analysis, the research undergoes a non-parametric Friedman Test. This study selects relevant attributes from three clinical datasets from the Machine Learning Repository maintained by the University of California Irvine and achieved an accuracy of 86% for the Breast Cancer Wisconsin (Diagnostic) dataset, 89% for the Diabetic Retinopathy Debrecen dataset, and 91% for the EEG Eye State dataset respectively. When compared with other machine learning classifiers the proposed approach performed well with feature selection compared with other machine learning classifiers.

Optimized Deep Convolutional Neural Network for the Prediction of Breast Cancer Recurrence

With more than 2.1 million new cases of diagnosis each year, breast cancer is considered to be the most prevalent women disease. Within 10 years, nearly 30% patients who got cured at early-stages experienced cancer recurrence. Recurrence is a crucial aspect of breast cancer behaviour that is inseparably linked to mortality. Despite its importance, the significant proportion of breast cancer datasets rarely include it, which makes research into its prediction more challenging. It is still difficult to predict who will experience a recurrence and who won't, which has implications for the treatment that goes along with it. Clinicians treating breast cancer may be able to avoid ineffective overtreatment if Artificial Intelligence (AI) methods are developed that can forecast the likelihood of breast cancer recurrence. This work proposes a novel automatic breast cancer recurrence classification and prediction system incorporating novel Deep Convolutional Neural Network (DCNN) algorithm. The proposed DCNN model is deployed on Wisconsin Breast Cancer dataset for further evaluation. The role of AI in forecasting recurrence is examined in this work. The experimental results were analysed for various combination of train and validation dataset. The accuracy, precision, recall and F1-score for the proposed DCNN was calculated as 97.63 %, 98.57 %, 96.84 %, 97.89 % respectively.

A study on the crucial indicators for breast cancer detection using machine learning algorithm

Since breast cancer is the most serious disease affecting women, early detection comes as a priority. The Wisconsin Breast Cancer Dataset (WBCD), which was retrieved from the UCI database, has been applied in numerous studies in recent years to help with the definitive diagnosis. Machine learning (ML) algorithms, such as K-Nearest Neighbor (KNN), Logistic Regression (LR), Decision Tree (DT), Random Forest (RF), Naive Bayes (NB), Support Vector Machine (SVM), and Neural Network (NN) can be used to attain the upshot. Although these algorithms make predictions well, advantages cannot overshadow drawbacks because the outcome is circumstantial by the peculiar dataset itself and cannot draw a direct conclusion reflecting the deeper issue. To implement ML skills to figure out the factors that influence the prediction most in a statistical dimension, this paper uses the dataset above, compares five methods, and chooses three best classifiers: KNN, RF, and SVM. After selection, the author eliminates every single variable each time to get the accuracy, and compares them with the full model’s accuracy. Having controlled variables, it can be informed that Clump Thickness and Bare Nuclei are the factors that matter most.

An Analysis of the k-Nearest Neighbor Classifier to Predict Benign and Malignant Breast Cancer Tumors

Because of Breast Cancer's high mortality rate and being a leading cause of death among women worldwide, there has been importance given to machine learning (ML) algorithms to detect early signs of benign and malignant tumors effectively. Assistance from ML classifiers allows for a more efficient evaluation of mammographic results, surpassing the capabilities of radiologists who manually classify extensive patient data. This study aims to evaluate the effectiveness of the k-Nearest Neighbor (kNN) classifier in characterizing cancer tumor stages based on concavity, texture, area, perimeter, and smoothness. We employ scatterplots to differentiate between benign and malignant classes using the Breast Cancer Wisconsin Dataset (WBCD) from the University of California at Irvine Machine Learning Repository. Employing the k-Fold Cross Validation (k-FCV) technique, we determine the optimal value for k to assign anonymous data to their respective categories. The analysis conducted in this study finds that the most favorable value for the hyperparameter k is 12, resulting in a highly effective diagnostic outcome from administering four distinct tests. Given the absence of a predefined value for the k parameter, guesswork could lead to accuracy errors and misdiagnosis; therefore, employing k-FCV provides a more precise approach to determining the optimal class for unknown tumor attributes. Additionally, preprocessing of this dataset and measuring how different data splits impact accuracy are used to organize the data effectively and achieve reliable results. Recognizing that early detection is essential in preventing Breast Cancer-related deaths, ML techniques like kNN can greatly reduce mortality rates associated with the disease.

An ensemble learning-based framework for breast cancer prediction

Breast cancer is a disease characterised by abnormal cell growth in the breast, with various types and unique characteristics depending on the malignant cells involved. It predominantly affects women, and researchers in the field of clinical sciences are increasingly interested in leveraging Artificial Intelligence (AI) techniques to predict and diagnose breast cancer. This study utilises the widely-used Wisconsin Breast Cancer Dataset (WBCD) from the University of California Irvine (UCI) machine learning repository. The dataset contains 30 features, including mean, standard error, and “worst” values, providing insights into different aspects of breast cancer. A stacked ensemble classifier is proposed to evaluate the effectiveness of the proposed model, incorporating multiple machine learning algorithms such as the Decision Tree Classifier, AdaBoost Classifier, Gaussian Naive Bayes (GaussianNB), and Multi-layer Perceptron Classifier (MLPClassifier). Various performance measures, including the Receiver Operating Characteristic Curve (ROC curve), Area Under the Curve (AUC), specificity, F1-score, sensitivity, and accuracy, are used to assess the model’s performance. The results demonstrate that the proposed ensemble technique achieves an accuracy of 97.66%, surpassing the performance reported in existing literature. This highlights the superior performance of the developed model compared to previous approaches. The study underscores the potential of AI techniques and machine learning algorithms in advancing breast cancer prediction and diagnosis, offering promising avenues for improving clinical decision-making and patient outcomes.

RAU: Novel Activation Function for Deep Learning Neural Network

In Deep learning neural networks (DNNs) activation functions perform a vital role. In each neuron activation function is responsible for generating output signals from given input signals. Hence, activation function is one of the factors that influence the performance of DNN. A novel activation unit RAU (Reciprocal activation unit) is proposed in this paper. Most of the popular algorithms given more importance to positive signals, but proposed method handles the negative and positive inputs equally. The proposed RAU tested with both multiclassification and binary classification datasets. Iris flower and Wisconsin Breast Cancer datasets are used for the analysis. In Breast cancer dataset RAU provides 99.25% and 97.08% accuracy for classification of train and test sets respectively. In Iris dataset RAU provides 99.05% and 97.78% accuracy for the classification of train and test sets. Analysis of the same datasets are performed with the existing activation functions- Sigmoid, RMAF, Swish, Tanh and ReLU. Results showed that RAU performed better than other activation functions.

Implementation of SMOTE and whale optimization algorithm on breast cancer classification using backpropagation

Breast cancer, which is characterized by uncontrolled cell growth, is the primary cause of mortality among women worldwide. The unchecked proliferation of cells leads to the formation of a mass or tumor. Generally, the absence of timely and efficient treatment contributes to this phenomenon. To prevent breast cancer, one of the strategies involves the classification of malignant and non-malignant types. For this particular investigation, the Breast Cancer Wisconsin dataset (original) comprising 699 instances with 11 classes and 1 target attribute was utilized. Synthetic Minority Oversampling (SMOTE) was employed to balance the dataset, with the Backpropagation classification algorithm and the Whale Optimization Algorithm (WOA) serving as optimization techniques. The main objectives of this study were to analyze the impact of the backpropagation method and SMOTE, examine the effect of the backpropagation method in conjunction with WOA, and assess the outcome of using the backpropagation method and SMOTE after incorporating WOA. The evaluation of the study's findings was performed using a confusion matrix and the Area Under the Curve (AUC) metric. The research outcomes based on the application of backpropagation yielded an accuracy rate of 96%, precision of 94%, recall of 95%, and an AUC of 96%. Subsequently, upon implementing SMOTE and WOA, the performance of the backpropagation method improved, resulting in an accuracy rate of 99%, precision of 97%, recall of 97%, and an AUC of 98%. This notable enhancement in performance suggests that the utilization of SMOTE and WOA effectively enhances accuracy. However, it is important to note that the observed improvements are relatively modest in nature.

Random logistic machine (RLM): Transforming statistical models into machine learning approach

Data science is booming with big data, and machine learning provides better predictive analyses. However, conventional statistical models can effortlessly interpret the effect estimates, and the prediction models are generally in a closed form. Therefore, this research integrates the logistic regression model’s core with the Random Forest structure to create a blended novel machine learning method, the Random Logistic Machine (RLM). In this way, the new approach preserves the statistical and machine learning advantages. Computer simulation studies examined the predictive ability of RLM, random forest, and Logistic Regression under various scenarios. The results showed that the RLM delivers a comparable performance to Random Forests and Logistic Regression. An application to the Breast Cancer Wisconsin (Diagnostic) Data Set also demonstrates the superior performance of the new approach.

Comparision of Different Classifiers for Prediction of Breast Cancer

The cell formed in the breast are known as breast cancer. It occurs mainly in women and it may occur rarely in men also. It is considered as the most common ailment that can lead to large number of death in females every year. In spite of the factuality that cancer is treatable and can be relieve if treated at its early stages; many patients are screened for cancer only at a very late stage. Data mining technique such as classifications provides an efficient technique to classify data, where these methods are commonly used for diagnostic decision making. The Machine learning techniques propound various methods such as statistical and probabilistic methods which allow system to learn from past experiences to distinguish and identify patterns from a standard dataset. The research work presents a review of machine learning techniques which can be used in breast cancer disease detection by applying algorithms on breast cancer Wisconsin data set. Algorithms such as Navies Bayes, Random Forest, Support Vector Machine, Adaboost and Decision Trees were used. The result outcome shows that Random Forest performs better than other techniques.

Comparison of Machine Learning and Deep Learning Algorithms for Classification of Breast Cancer

Statistical data from the American Cancer Society which shows that breast cancer ranks first with the highest number of cases of all types of cases of malignant tumors (cancer) worldwide. through a data mining process that is used to extract information and data analysis, a classification process can be carried out to carry out further analysis of the pattern of a data. The dataset used in this study is the Breast Cancer Wisconsin (Diagnostic) Dataset obtained from UCI Machine Learning. The purpose of this study is to compare five algorithms, namely Logistic Regression, K Neighbors Classifier (KNN), Decision Tree Classifier, Deep Neural Network, Genetic Algorithm. The results showed that deep neural network algorithms and multilayer perceptron-genetic algorithms get 96% accuracy, logistic regression algorithms have 96% accuracy, then KNN with 94%, and decision tree classifier with 92%.

Role of transfer functions in PSO to select diagnostic attributes for chronic disease prediction: An experimental study

Particle Swarm Optimization (PSO) is a classic and popularly used meta-heuristic algorithm in many real-life optimization problems due to its less computational complexity and simplicity. The binary version of PSO, known as BPSO, is used to solve binary optimization problems, such as feature selection. Like other meta-heuristic optimization techniques designed on the continuous search space, PSO uses the transfer functions (TFs) to map the candidate solutions to the discrete search space in BPSO, and these TFs play a vital role to get the desired results. Over the years, many forms of TFs have been introduced in the literature, most of which fall under one of the five families - Linear, S-shaped, V-shaped, U-shaped, and Time-varying Mirrored S-shaped TFs. The goal of this study is to determine an appropriate setup constituting a TF and a classifier for feature selection from different types of clinical data. In this study, the impacts of the five TF families have been investigated, considering one from each family for the selection of attributes/features, while predicting disease using diagnosis or medical reports. The classification tasks are carried out using four standard classifiers: Support Vector Machine, Decision Tree, K-Nearest Neighbors, and Gaussian Naive Bayes. For experimental purposes, we have used four publicly available datasets namely, the UCI Heart Disease dataset, Wisconsin Breast Cancer dataset, UCI Chronic Kidney Disease dataset, and PIMA Indians Diabetes dataset. After an exhaustive set of experiments, we have obtained 96.72%, 99.82%, 100.00%, and 84.41% disease prediction scores in the best case for Heart disease, Breast Cancer, Chronic Kidney disease, and Diabetes, respectively. The obtained results are comparable to several state-of-the-art methods considered here for comparison. The present study helps in selecting a suitable BPSO setup (i.e., a TF and a classifier) to select important diagnostic attributes useful to design a computer-aided decision support system for the said diseases.

Breast cancer diagnosis and management guided by data augmentation, utilizing an integrated framework of SHAP and random augmentation.

Recent research indicates that early detection of breast cancer (BC) is critical in achieving favorable treatment outcomes and reducing the mortality rate associated with it. With the difficulty in obtaining a balanced dataset that is primarily sourced for the diagnosis of the disease, many researchers have relied on data augmentation techniques, thereby having varying datasets with varying quality and results. The dataset we focused on in this study is crafted from SHapley Additive exPlanations (SHAP)-augmentation and random augmentation (RA) approaches to dealing with imbalanced data. This was carried out on the Wisconsin BC dataset and the effectiveness of this approach to the diagnosis of BC was checked using six machine-learning algorithms. RA synthetically generated some parts of the dataset while SHAP helped in assessing the quality of the attributes, which were selected and used for the training of the models. The result from our analysis shows that the performance of the models used generally increased to more than 3% for most of the models using the dataset obtained by the integration of SHAP and RA. Additionally, after diagnosis, it is important to focus on providing quality care to ensure the best possible outcomes for patients. The need for proper management of the disease state is crucial so as to reduce the recurrence of the disease and other associated complications. Thus the interpretability provided by SHAP enlightens the management strategies in this study focusing on the quality of care given to the patient and how timely the care is.

Small samples-oriented intrinsically explainable machine learning using Variational Bayesian Logistic Regression: An intensive care unit readmission prediction case for liver transplantation patients

Recently, machine learning has revolutionized medical diagnosis and prediction, rivaling human experts in accuracy. However, the limited interpretability poses challenges in meeting stringent medical decision standards. To facilitate interpretable predictive inference, this article proposes a small samples-oriented intrinsically explainable machine learning model, an Optimal Variational Bayesian Logistic Regression (OVBLR) model with a salient feature estimation strategy (OVBLR-SFE). OVBLR-SFE sequentially learns from limited labeled samples, mining disease-related risk factors to provide intrinsic interpretability to its predictive inference automatically. The model achieves this by reasonably approximating the posterior probability through the proposed OVBLR model to estimate the feature weight and influential effect on model outputs to facilitate salient feature selection. The effectiveness and superiority of OVBLR-SFE are demonstrated through extensive experiments on four benchmark medical datasets from the UCI repository, including the Bone Marrow Transplant: Children Data Set, Breast Cancer Wisconsin (Original) Data Set, SPECT Heart Data Set, and Heart Disease Data Set, as well as a real-world case of intensive care unit readmission prediction. Experimental results reveal that the OVBLR-SFE can achieve high accuracies of 92.02%, 97.21%, 86.71%, and 84.47%, respectively, with an average classification accuracy of 90.10% stably on the four UCI datasets. Especially, OVBLR-SFE can accurately infer significant features that align with that obtained by the post-hoc interpretation approaches: SHAP and AcME, demonstrating remarkable interpretability. In the real application, the proposed method achieved a readmission prediction accuracy of 88.11% in predicting the readmission probabilities of liver transplantation patients. Notably, the inferred salient features, such as total Intensive Care Unit length of stay (ICUTime), N-terminal pro-brain natriuretic peptide(NTproBNP), Operating time of surgery(OperationTime_h), and intraoperative red blood cell transfusion (RBCT), emerges as crucial in readmission prediction, aligning with the assessments of clinical experts. The source code of this study can be accessed at https://github.com/xqw42/OVBLR-SFE.

Hybrid Mahalanobis Taguchi System with Binary Whale Optimisation Feature Selection for the Wisconsin Breast Cancer Dataset

The Mahalanobis-Taguchi System (MTS) is a statistical approach used in breast cancer research to facilitate early detection and promote efficient treatment. The technique analyses mammogram images for significant features using a multivariate statistical analysis technique. It combines the Mahalanobis distance (MD) and Taguchi's method to determine the differences between benign and malignant samples. While orthogonal array (OA) has been widely used in MTS, it has been criticised for providing suboptimal results due to insufficient coverage of feature combinations during the feature optimisation process. To address this issue, the Binary Whale Optimisation Algorithm (BWOA) is proposed as an improved search algorithm for MTS. This paper aims to develop a novel hybrid method that enhances the efficiency of the Mahalanobis Taguchi System (MTS). The performance of feature selection ability due to different MTS hybrid algorithms were also compared. BWOA simulates the hunting behaviour of humpback whales and works by exploring new regions of the solution space, gradually narrowing the search space, and fine-tuning the solution. MTS-BWOA demonstrated its enhanced capability in feature optimisation compared to traditional MTS methods and has the potential to be applied in other medical imaging domains.