Since the IPv6 Wireless Personal Area Network (6LoWPAN) can be utilized for information dissemination, this network gains significant attention in recent years. Proxy mobile IPv6 (PMIPv6) is standard for mobility control based on network at entire IP wireless applications. But, group-based body area networks cannot respond effectively. A new improved group flexibility system decrease the number of control messages contain router requests as well as advertising messages when compared to the group-based PMIPv6 protocol, in order to minimize delay and signaling costs. The IEEE 802.15.4 standard for low-power personal area networks (6LoWPAN) complies through IPv6-compliant MAC and physical layers. If the default parameters, excessive collisions, packet loss, and great latency occur arbitrarily in high traffic by default MAC parameters while using a great number of 6LoWPAN nodes. The implemented Whale optimization algorithm is based on artificial neural network optimization, genetic algorithm or particle swarm optimization to choose and authenticate MAC parameters. This manuscript proposes a novel intelligent method for choosing optimally configured MAC 6LoWPAN layer set parameters. Results of simulations based on the metrics such as Average delay time (ADT), Average signaling cost, Delivery ratio, Energy consumption, Latency, Network Life time (Nlt), Packet Overhead (PO), Packet loss. The performance of the proposed method provides 19.08%, 25.87%, 31.98%, 26.98%, 31.98%, 26.98% and 23.89% lower Latency, 12.67%, 25.98%, 31.98%, 26.98%, 27.98%, 31.97% and 27.85% lower Packet Overhead and 19.78%, 27.96%, 37.98%, 18.09%, 28.97%, 27.98% and 56.04% higher Delivery ratio compared with the existing methods such as 6LoWPAN-NUM-OHCA-FFA, 6LoWPAN-GTCCF-PSO, 6LoWPAN- DODAG-ACO, 6LoWPAN- MAC-GA-PSO, 6LoWPAN-NCG-DTC-NGIPSA and 6LoWPAN-TDMA-GTS-SHJA algorithms respectively.