The spectral dependency of single-junction solar cells limits the conversion capability of the photovoltaic modules. The above property also causes a rise in the temperature of the photovoltaic device. High module temperature further limits the output of a photovoltaic system besides adversely affecting the building cooling loads if integrated into a building. This research work analyses the effectiveness of a spectrally selective layer in the performance of a double pane semi-transparent photovoltaic window system with different airflows. A validated EnergyPlus simulation model has been used in the study. The other software used in the work are WINDOW7.3 and Optics6. In the present study, around a 35% rise in photovoltaic conversion has been observed due to the application of a spectrally selective front layer. A major finding of this research is that the application of a spectrally selective layer in photovoltaic systems like double pane windows will be highly beneficial if it transmits 100% of the effective wavelength range. Hence it opens a new dimension to the researchers to develop spectrally selective materials as per the applied solar photovoltaic module. • A.M 1.5 solar spectrum contains only 62.8% useful energy for CdTe module. • Application of spectrally selective glass reduces module temperature by 22 °C. • Spectrally selective glass produces quality spectrum for better PV conversion. • Using hot window cavity air, room temperature can be increased by 2 °C in winter. • Highly transparent spectrally selective glass has great importance in BIPV sector.