Gable roofs with overhangs (eaves) are the common constructions of low-rise buildings on the southeastern coast of China, and they were vulnerable to typhoons from experience. The wind pressure distributions on gable roofs of low-rise buildings are investigated by a series of wind tunnel tests which consist of 99 test cases with various roof pitches, height-depth ratios and width-depth ratios. The block pressure coefficients and worst negative (block) pressure coefficients on different roof regions of low-rise buildings are proposed for the main structure and building envelope, respectively. The effects of roof pitch, height-depth ratio, and width-depth ratio on the pressure coefficients of each region are analyzed in detail. In addition, the pressure coefficients on the roofs for the main structure and building envelope are fitted according to roof pitch, height-depth ratio and width-depth ratio of the low-rise building. Meanwhile, the rationality of the fitting formulas is verified by comparing the fitting results with the codes of different countries. Lastly, the block pressure coefficients and worst negative pressure coefficients are recommended to guide the design of low-rise buildings in typhoon area and act as references for the future’s modification of wind load codes.