Coastal long-span bridges are intensively constructed along the western Pacific coast. While the coast is frequently disturbed by typhoons. Given that a coastal long-span bridge will experience a number of typhoons during its service life, it is important to have an understanding of the wind fields formed by typhoons with different crossing paths and corresponding structural dynamic responses. Wind and acceleration data of the Xihoumen Bridge under the influence of onshore, offshore, and landfalling typhoons were acquired by the structural health monitoring system (SHMS). Wind field features of typhoons with three types of paths were compared. The landfalling Typhoon In-fa was used to investigate the differences of wind-induced structural dynamic responses under the influence of each typhoon structural region. The covariance-driven stochastic subspace identification (SSI-COV) was used to identify the modal parameters of the bridge. The results revealed that wind field features at bridge site varied with typhoon crossing paths. The SSI-COV accurately identified the structural frequencies of first 15 vertical modes using the acceleration data under the influence of spiral rainband. The first eyewall has the most detrimental wind conditions to the bridge because the stiffening girder vibrated violently in this region.