Article1 February 1928Evidence Concerning the Effect of Insulin On Carbohydrate ToleranceWM. M. LEFEVRE, A.B., M.D.WM. M. LEFEVRE, A.B., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-1-8-607 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPrevious to the discovery of insulin the treatment of diabetes mellitus consisted entirely of dietary measures. Various writers outlined methods of procedure which were calculated to maintain a sugar free urine and still keep the patient fairly well nourished. These experiments met with a variable degree of success, depending on the severity of the disease in the patients under their care.The discovery of insulin changed the treatment of this malady as no treatment has been changed before. The early writings on insulin which appeared shortly after the completion of the experimental work which led to its discovery, give one...Bibliography(1) BANTING FG et al.; Canadian Medical Association Journal 12: 141, March, 1922. MedlineGoogle Scholar(2) BRACE WM, Insulin and Carbohydrate Tolerance. Annals of Internal Medicine, Volume 1, No. 4-203. October, 1927. Google Scholar(3) PETTY OH, The Practical Use of Insulin in the Treatment of Diabetes. International Clinics Volume 2, Series 33, pp. 37. Google Scholar(4) WOODYATT RT, Objects and Methods of Diet and Adjustment to Diabetes. Archives Internal Medicine 28: 125, 1921. CrossrefGoogle Scholar(5) NEWBURGH LH, High Fat Diet in the Treatment of Diabetes Mellitus. Medical Clinics North America. 6:1119, March, 1923. Google Scholar(6) MCCALLUM WG, Hypertrophy of Islands of Langerhans in Diabetes Mellitus. J. A. M. Sc. 133-432. Google Scholar(7) WILLIAMS JR, Result of Long Continued Use of Insulin in Diabetes. New York State Journal of Medicine 27:49 Jan. 15, 1927. Google Scholar(8) JOHN HJ, Diabetes—One Thousand Cases. Archives Internal Medicine 39:1-162, January, 1927. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Muskegon, Michigan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1928Volume 1, Issue 8Page: 607-612KeywordsCarbohydratesDiabetes mellitusInsulinPatientsUrine Issue Published: 1 February 1928 PDF downloadLoading ...