Statement of the problem: The estimation of the width of a missing maxillary central incisor is of a paramount importance for prosthodontic applications. Several facial anatomic land marks have been used to accomplish this purpose with varying degrees of certainty .This study explores the possibility of using labial philtrum to correlate and predict the width of maxillary central incisor. Aim : 1. To estimate the correlation between the width of maxillary central incisor and the width of the philtrum. 2. To predict the width of maxillary central incisor utilizing the philtrum width as a guide. Methodology : A prospective, observational, open label study design was performed to evaluate the correlation between the maxillary central incisor width and philtral width in 200 Indian dentate adult human subjects satisfying the inclusion and exclusion criteria. The maxillary central incisor width denoted as variable y and the philtral width as variable x and width was measured in millimetres and the values were subjected to statistical analysis to estimate correlation and regression. Statistical Analysis: Pearson's correlation coefficient was worked out (r) and a regression equation was formulated and analyzed using the SPSS statistical software. The correlation coefficient worked out was r = + 0.99, coefficient of determination r 2 = 0.96 and the regression intercept was -5.99. Mean central incisor width was 8.5 ±0.65 mm and mean philtral width was 14.4 ±0.42 mm. Inference: A strong positive correlation between the width of the philtrum and width of maxillary central incisor was observed (r = + 0.99). The maximum philtral width subtracted by 6 mm will provide the estimate for the width of maxillary central incisor.