Widespread Deficiency Research Articles

Research, development and adoption for the north Australian beef cattle breeding industry: an analysis of needs and gaps

This review seeks to analyse and prioritise needs and gaps in research and development (R&D) for the north Australian beef cattle breeding industry, and to advise on options to increase rates of adoption and successful implementation of this R&D. The material reviewed includes the peer-reviewed literature as well as industry reports and other relevant publications in three targeted areas of R&D deemed to be important by industry leaders and supporting scientists: (i) breeding herd management, (ii) feedbase management, and (iii) management of environmental sustainability. For breeding herd management, the need for uniform definition and consistent utilisation of appropriate productivity metrics is highlighted, with emphasis on assessment of maternal reproductive efficiency in terms of weaning (or branding) rates. Priority is given to the urgent need for reliable means of remotely assessing causes of neonatal calf mortality to enable the development and application of management interventions that improve calf survival rates. The highest priority for feedbase management is to increase producer awareness and willingness to adopt stocking rates that are appropriately matched to the long-term carrying capacity of native rangeland pastures that predominate in northern Australia. Other opportunities include increasing the use of perennial, tropically adapted legumes, where conditions permit, to improve soil fertility and nitrogen intake of cattle, and devising strategies to overcome widespread phosphorus deficiency through diagnosis and supplementation, especially in the wet season. In order to enhance environmental sustainability in the face of climate change, priorities include improving producer awareness and use of increasingly robust tools for predicting key weather events, as well as developing genetic strategies to increase heat tolerance of cattle and evaluating management interventions to mitigate heat stress. Conclusions drawn from these sections are summarised and used to make recommendations on priorities for increasing adoption of existing research-proven practices and technologies, and for further R&D on selected topics.

A Review of Essential Microelements in the Immune System

The immune system is the set of cells and organs that intervene in the body's defense against certain antigens, foreign to the body. This set includes both elements with rapid action and thus belonging to non-specific immunity, and also, elements that provide a slower response, but, with high specificity against each antigen. Nonspecific immunity sums up both cellular and humoral elements, which react quickly on foreign substances and microorganisms. On the other hand, adaptive immunity is based on the existence of lymphocytes, which develop a response, albeit slower, with a high specificity through antibodies secreted by B lymphocytes. Zinc deficiency is the second most widespread micronutrient deficiency. This compound is indispensable for the human body because it is a cofactor for many enzymes including alkaline phosphatase, dismutase superoxide, metalloproteinases. Moreover, zinc is included in the structure of growth and transcription factors and it participates in the cell communication within the immune system. Selenium is an essential trace element, being involved in many biological processes. It is part of a structural component of the amino acid selenocysteine, one of 25 selenoproteins, which are involved in the body's immune defense. Raising the awareness of iron deficiency, recent studies emphasize that it is the most common mineral deficiency worldwide. As it is already well known, iron is particularly important in the transport of oxygen, but its essential roles are not only limited to that. Besides, it is a constituent part of some metalloproteins and a cofactor for many other enzymes. Moreover, iron takes part of ATP synthesis. Therefore, the lack of iron has multiple repercussions on the whole organism, including the immune system.

Evolution of soil fertility research and development in Ethiopia: From reconnaissance to data-mining approaches

Summary Meeting the burgeoning global demand for both food and energy requires substantial yield increases through the efficient use of inputs like fertilizers. Prompted by the result of a soil survey expedition in the late 1950s, which signaled a widespread deficiency of nitrogen (N) and phosphorus (P), plant nutrition research in Ethiopia began in the 1960s, focusing on the response of prioritized cereals – tef (Eragrostis tef), wheat (Triticum aestivum), and maize (Zea mays) – to the application of N and P fertilizers. Nationwide on-farm trials conducted in the early 1970s led to a blanket recommendation of 64 kg N ha−1 and 20 kg P ha−1, irrespective of the crop and soil types, which were applied in the form of di-ammonium phosphate (18-46-0) and urea (46-0-0), respectively. Research conducted in the 1980s across agro-ecological and edaphic spectrum recommended 30–138 kg N ha−1 and 0–50 kg P ha−1, respectively. However, studies show that only 30–40% of the smallholder farmers use fertilizers at a rate less than recommended (on average at 37–40 kg ha−1). This rate reflects limited supply, high prices, and the low and declining crop response to fertilizers. As a result, cereal yields increased only 10% despite a fivefold increase in fertilizer application since the 1980s. Owing to the limited and declining crop response and the increased price of fertilizer in the 1990s, research on the integrated application of inorganic and organic sources of fertilizers was initiated. Although the integrated use resulted in increased yield and better economic benefits, it was not mainstreamed into the national agricultural extension system. The soil survey expedition that began in 2011 culminated in the mapping of the soil nutrient status using literature-based critical limits. The maps have persistently revealed the deficiency of N, P, potassium, sulfur, zinc, and boron across the surveyed areas. Despite the above efforts, the data sets generated through the soil surveys conducted at different times during the last half-century and the agronomic research during the same period have never been fully exploited. It is believed that the recent development in data mining and machine-learning approaches creates the opportunities to use the data sets in conjunction with other covariates in order to generate evidence that helps to make better decisions both at strategic and operational levels. The development of decision support tools based on such large datasets and analytical capacity is believed to facilitate better-informed decisions that lead to increased resource use efficiency and sustainability.

Yield response of tef (Eragrostis tef) to nitrogen, phosphorus, potassium and sulphur under balanced fertilization on Vertisols in different agroecological zones of Ethiopia

Summary Nutrient deficiency is a major constraint in tef (Eragrostis tef (Zucc.) Trotter) production in Ethiopia. In the past, a blanket recommendation of nitrogen (N) and phosphorus (P) fertilizers has been applied regardless of the diversity of agroecological zones and soil types. As crop responses declined with widespread deficiencies of nutrients, farmers have lost interest in applying the recommended fertilizer rates. The present study was conducted with the objective of quantifying the response of tef to different rates of N, P, potassium (K) and sulphur (S) fertilizers under balanced application of the nutrients other than the one under investigation. In each region, the same set of trials was implemented on farmers’ fields for three years. All trials were implemented on Vertisols across four agroecological zones (AEZs). The treatments were seven rates of N, six rates each of P and S and eight rates of K with a basal application of zinc (Zn) and boron (B). The results showed that the most limiting nutrient is N followed by P in each agroecological zone on the Vertisols. There was clear evidence of increases in grain yield with increasing rates of N and P, but the responses to K and S rates did not follow clear trends across AEZs. With balanced application of the other nutrients, 23–92 kg N ha−1 increased grain yield by 11–92%, while 10–40 kg P ha−1 increased yields by 12–33% over the control in the different AEZs. Based on results from dose–response models, it is concluded that the agronomic optimum rates for tef production are 69 kg N, 20 kg P, 30 kg K and 10 kg S ha−1 in the cool sub-moist mid-highlands and the tepid sub-humid mid highlands; 92 kg N, 30 kg P, 15 kg K and 10 kg S ha−1 in tepid moist mid highlands but 69 kg N, 10 kg P, 15 kg K and 10 kg S ha−1 in the tepid sub-moist mid highlands. On Vertisols not covered by this study, these recommendations should be subject to appropriate soil and plant analysis. We also recommend further studies on the nutrient requirement of tef on other soil types and AEZs.

Enrichment of Zinc and Iron Micronutrients in Lentil (Lens culinaris Medik.) through Biofortification.

Biofortification of pulse crops with Zn and Fe is a viable approach to combat their widespread deficiencies in humans. Lentil (Lens culinaris Medik.) is a widely consumed edible crop possessing a high level of Zn and Fe micronutrients. Thus, the present study was conducted to examine the influence of foliar application of Zn and Fe on productivity, concentration, uptake and the economics of lentil cultivation (LL 931). For this, different treatment combinations of ZnSO4·7H2O (0.5%) and FeSO4·7H2O (0.5%), along with the recommended dose of fertilizer (RDF), were applied to the lentil. The results of study reported that the combined foliar application of ZnSO4·7H2O (0.5%) + FeSO4·7H2O (0.5%) at pre-flowering (S1) and pod formation (S2) stages was most effective in enhancing grain and straw yield, Zn and Fe concentration, and uptake. However, the outcome of this treatment was statistically on par with the results obtained under the treatment ZnSO4·7H2O (0.5%) + FeSO4·7H2O (0.5%) at S1 stage. A single spray of ZnSO4·7H2O (0.5%) + FeSO4·7H2O (0.5%) at S1 stage enhanced the grain and straw yield up to 39.6% and 51.8%, respectively. Similarly, Zn and Fe concentrations showed enhancement in grain (10.9% and 20.4%, respectively) and straw (27.5% and 27.6% respectively) of the lentil. The increase in Zn and Fe uptake by grain was 54.8% and 68.0%, respectively, whereas uptake by straw was 93.6% and 93.7%, respectively. Also the benefit:cost was the highest (1.96) with application of ZnSO4·7H2O (0.5%) + FeSO4·7H2O (0.5%) at S1 stage. Conclusively, the combined use of ZnSO4·7H2O (0.5%) + FeSO4·7H2O (0.5%) at S1 stage can contribute significantly towards yield, Zn and Fe concentration, as well as uptake and the economic returns of lentil to remediate the Zn and Fe deficiency.

​Yield Attributes, Yield and Nutrient Uptake of Rice (Oryza sativa L.) as Influenced by Zinc Fortified Briquettes in Medium Black Soil

Background: Briquettes is more efficient than conventionally applied nutrients as it reduce the loss of nutrients by obtaining higher yield and decreased the expenditure cost of fertilizers. Indian soils are 49 per cent deficient in zinc which is characterized by widespread Zn deficiency in human beings. Methods: Three different zinc fortified briquettes viz., UB-DAP, UB-suphala and UB-KAB were tested in field experiments during kharif season of 2016-19 to compare and calculate variations in yield, yield attributing characters and nutrients uptake by rice (Oryza sativa L.). Result: The results showed that treatment UB-KAB fortified with 10 kg ZnSO4.7H2O ha-1 (T8) registered higher growth, yield parameters and Zn concentration in grain indicating zinc-sulfate-heptahydrate (ZSHH) offers vital solution to curtail Zn malnutrition. Further, UB-KAB fortified through ZSHH (T8) significantly enhanced the grain (55.2 q ha-1) and straw (63.6 q ha-1) yield of rice over RDF and absolute control. Application of UB-KAB fortified with 10 kg ZnSO4.7H2O ha-1 (T8) significantly increased nutrient uptake of N (97.2 kg ha-1), P (20.2 kg ha-1), K (95.5 kg ha-1), Zn (262.4 g ha-1) and S (53.9 kg ha-1) over fertilizer control (75% RDF) and absolute control. The applications of KAB fortified with zinc sulphate assume great significance in improving rice productivity.

Identity, Ambiguity, and Professionalism: Dilemmas for the Diocesan Advisor in the Republic of Ireland

A deficit in empirical studies regarding the role of the Diocesan Advisor at second-level schools in the Republic of Ireland prompted research in this area. The findings of a study carried out by the authors are outlined in this article. Perspectives of 19 Diocesan Advisors were gathered qualitatively. The concept of “visible” and “invisible” maps provided a framework. In Ireland, State inspection relies on visible mapping of inspection processes that are accessible to all stakeholders. The Diocesan Advisor, on behalf of the bishop, uses invisible maps, observing how the school is living out its Catholic remit and how religious education is carried out within the curriculum. The study identified that the role is under-resourced and lacks clarity, resulting in a widespread deficiency in the monitoring of Catholic schools’ identity and the non-examinable religious education currently on the curriculum. The study further revealed an uncertain future for the role of the Diocesan Advisor in a changing landscape. A discussion on the implications of the findings is included, and possible options for the role in the future are explored.

Myelodysplastic Syndromes: A More Global 5-Hydroxymethylcytosine Deficiency Disorder Than Suggested By the Presence of TET2 Mutations

Myelodysplastic Syndromes: A More Global 5-Hydroxymethylcytosine Deficiency Disorder Than Suggested By the Presence of TET2 Mutations

Evaluation of Liquid Potassium Fertilizer on Yield and Yield Components of Potato Under Irrigation on Nitisols in Central Highlands of Ethiopia

Nutrient deficiency is a major constraint for potato ( S olanum t u berosum L.) production in Ethiopia. Potato response to potassium fertilizer declined with widespread deficiencies of nutrients other than N and P, farmers are discouraged to apply such fertilizer recommendations. This study was, therefore, conducted for two years (2018-2019) on nitisols under irrigation to evaluate the response of potato to liquid potassium (K) fertilizer rates. The treatments were five (Negative control, recommended NPS, recommended NPS, recommended NPS + 3liter liquid K /ha, recommended NPS + 5 liter liquid K/ha, recommended NPS + 7liter liquid K/ha). The experiment was arranged in a randomized complete block design replicated four times on farmers’ fields. Results revealed that potato yield responded differently to the applied potassium fertilizer rates. Applications of 100% NP fertilizer with 5liter/ha liquid potassium fertilizer had a significant (p<0.05) effect on marketable tuber and total tuber yield of potato. In general application of liquid potassium fertilizer (100% NP fertilizer with 5liter/ha liquid K) indicates positive response on dray matter and specific gravity. In conclusion, based on the findings of the experiment with application of 5L/ha liquid potassium fertilizer with 100% recommended NP fertilizer are economically optimum for potato production. DOI: 10.7176/JBAH/11-22-01 Publication date: November 30 th 2021

Proteome-Scale Drug-Target Interaction Predictions: Approaches and Applications.

Drug-Target interaction predictions are an important cornerstone of computer-aided drug discovery. While predictive methods around individual targets have a long history, the application of proteome-scale models is relatively recent. In this overview, we will provide the context required to understand advances in this emerging field within computational drug discovery, evaluate emerging technologies for suitability to given tasks, and provide guidelines for the design and implementation of new drug-target interaction prediction models. We will discuss the validation approaches used, and propose a set of key criteria that should be applied to evaluate their validity. We note that we find widespread deficiencies in the existing literature, making it difficult to judge the practical effectiveness of some of the techniques proposed from their publications alone. We hope that this review may help remedy this situation and increase awareness of several sources of bias that may enter into commonly used cross-validation methods. © 2021 Cyclica Inc. Current Protocols published by Wiley Periodicals LLC.

Deficiency of phyto-available sulphur, zinc, boron, iron, copper and manganese in soils of India

Nutrient deficiencies in soil–crop contexts and inappropriate managements are the important reasons for low crop productivity, reduced nutritional quality of agricultural produce and animal/human malnutrition, across the world. The present investigation was carried out to evaluate nutrient deficiencies of sulphur (S) and micronutrients [zinc (Zn), boron (B), iron (Fe), copper (Cu) and manganese (Mn)] in agricultural soils of India for devising effective management strategies to achieve sustainable crop production, improved nutritional quality in crops and better animal/human health. A total of 2,42,827 surface (0–15 cm depth) soil samples were collected from agriculture fields of 615 districts lying in 28 states of India and were analysed for available S and micronutrients concentration. The study was carried out under the aegis of All India Coordinated Research Project on Micro- and Secondary-Nutrients and Pollutant Elements in Soils and Plants. The mean concentrations were 27.0 ± 29.9 mg kg−1 for available S, 1.40 ± 1.60 mg kg−1 for available Zn and 1.40 ± 4.70 mg kg−1 for available B, 31.0 ± 52.2 mg kg−1 for available Fe, 2.30 ± 3.50 mg kg−1 for available Cu and 17.5 ± 21.4 mg kg−1 for available Mn. There were variable and widespread deficiencies of S and micronutrients in different states. The deficiencies (acute deficient + deficient + latent deficiency) of S (58.6% of soils), Zn (51.2% of soils) and B (44.7% of soils) were higher compared to the deficiencies of Fe (19.2% of soils), Cu (11.4% of soils) and Mn (17.4% of soils). Out of 615 districts, > 50% of soils in 101, 131 and 86 districts were deficient in available S, available Zn and available B, respectively. Whereas, > 25% of soils in 83, 5 and 41 districts had deficiencies of available Fe, available Cu and available Mn, respectively. There were occurrences of 2-nutrients deficiencies such S + Zn (9.30% of soils), Zn + B (8.70% of soils), S + B (7.00% of soils) and Zn + Fe (5.80% of soils) to a greater extent compared to the deficiencies of Zn + Mn (3.40% of soils), S + Fe (3.30% of soils), Zn + Cu (2.80% of soils) and Fe + B (2.70% of soils). Relatively lower % of soils were deficient in 3-nutrients (namely S + Zn + B, S + Zn + B and Zn + Fe + B), 4-nutrients (namely Zn + Fe + Cu + Mn) and 5-nutrients (namely Zn + Fe + Cu + Mn + B) simultaneously. The information regarding the distribution of deficiencies of S and micronutrients (both single and multi-nutrients) could be used by various stakeholders for production, supply and application of right kind of fertilizers in different districts, states and agro-ecological regions of India for better crop production, crop nutritional quality, nutrient use efficiency, soil health and for tackling human and animal malnutrition.

Assessing Multi-Micronutrients Deficiency in Agricultural Soils of India

The deficiencies of nutrient elements and inappropriate nutrient management practices in agricultural soils of the world is one of the reasons for low crop productivity, reduced nutritional quality of agricultural produce, and animal/human malnutrition. We carried out the present study to evaluate the single and multi-nutrient deficiencies of sulfur (S) and micronutrients (zinc (Zn), boron (B), iron (Fe), copper (Cu) and manganese (Mn)) in agricultural soils of India for their effective management to achieve sustainable crop production, improved nutritional quality in crops and better animal/human health. Altogether, 24,2827 surface soil samples (0 to 15 cm depth) were collected from the agriculture fields of 615 districts in 28 states of India and were analyzed for available S and micronutrient concentration. The concentration of available S and micronutrients varied widely. There were variable and widespread deficiencies of S and micronutrients in different states. The deficiencies of S, Zn and B were higher compared to the deficiencies of Fe, Cu and Mn. There were occurrences of two-nutrient (namely S + Zn, Zn + B, S + B, Zn + Fe Zn + Mn, S + Fe, Zn + Cu and Fe + B), three-nutrient (namely S + Zn + B, S + Zn + B and Zn + Fe + B) and four-nutrient (namely Zn + Fe + Cu + Mn and Zn + Fe + Cu + Mn + B) deficiencies in different extents. This information could be used by various stakeholders for production, supply and application of the right kind of fertilizers in different districts, states and agro-ecological regions of India for better crop production, crop nutritional quality, nutrient use efficiency and soil and environmental health. This will also help in a greater way to address the issue of malnutrition in human/animals.

Implementation strategies for improving vitamin D status and increasing vitamin D intake in the UK: current controversies and future perspectives: proceedings of the 2nd Rank Prize Funds Forum on vitamin D.

A multi-disciplinary expert group met to discuss vitamin D deficiency in the UK and strategies for improving population intakes and status. Changes to UK Government advice since the 1st Rank Forum on Vitamin D (2009) were discussed, including rationale for setting a reference nutrient intake (10 µg/d; 400 IU/d) for adults and children (4+ years). Current UK data show inadequate intakes among all age groups and high prevalence of low vitamin D status among specific groups (e.g. pregnant women and adolescent males/females). Evidence of widespread deficiency within some minority ethnic groups, resulting in nutritional rickets (particularly among Black and South Asian infants), raised particular concern. Latest data indicate that UK population vitamin D intakes and status reamain relatively unchanged since Government recommendations changed in 2016. Vitamin D food fortification was discussed as a potential strategy to increase population intakes. Data from dose-response and dietary modelling studies indicate dairy products, bread, hens' eggs and some meats as potential fortification vehicles. Vitamin D3 appears more effective than vitamin D2 for raising serum 25-hydroxyvitamin D concentration, which has implications for choice of fortificant. Other considerations for successful fortification strategies include: (i) need for 'real-world' cost information for use in modelling work; (ii) supportive food legislation; (iii) improved consumer and health professional understanding of vitamin D's importance; (iv) clinical consequences of inadequate vitamin D status and (v) consistent communication of Government advice across health/social care professions, and via the food industry. These areas urgently require further research to enable universal improvement in vitamin D intakes and status in the UK population.

The Relationship between Serum Vitamin D Level and Psychosomatic Symptoms in Females in Mosul City

Background: A widespread severe deficiency of vitamin D (vit D) exists in Iraq, especially among women of reproductive age. Depression or anxiety is related to deficiency of vit D. These patients may present with psychosomatic symptoms which are symptoms with no sufficient organic cause in the body but from psychological causality. The study aimed to investigate the serum level of vit D in females with psychosomatic symptoms residing in Mosul City, Iraq and explore the effect of vitamin D3 (vit D3) supplements for treating psychosomatic symptoms.
 Methods: A total of 73 female patients aged 15–45 years presented with several symptoms. All patients underwent physical examination and psychiatric interviews. Patients with minimal to mild depression were selected. All included patients underwent investigation of first serum vit D level. The supplementation with vitamin D3 was started. The second serum vit D level was investigated at first post-improvement visit.
 Results: In the improved group, the post-supplementation serum vit D level was higher than that before the supplementation (p = 0.00). In addition, the vit D serum difference before and after its supplementation was greater in the improved group than the nonimproved one (p = 0.00). Patients not only experienced improvement in their mood swings, but also recovered from other recorded symptoms such as headache, fatigue, tiredness, and joint pain.
 Conclusion: This study revealed a noticeable association concerning serum levels of 25-OH D and mild depression in addition to psychosomatic symptoms in females living in Mosul City. Supplementation with suitable loading vit D3 dosages improved these symptoms showing a probable causal relationship.

The effect of soil properties on zinc lability and solubility in soils of Ethiopia – an isotopic dilution study

Abstract. Zinc (Zn) deficiency is a widespread nutritional problem in human populations, especially in sub-Saharan Africa (SSA). The Zn concentration of crops consumed depends in part on the Zn status of the soil. Improved understanding of factors controlling the phyto-availability of Zn in soils can contribute to potential agronomic interventions to tackle Zn deficiency, but many soil types in SSA are poorly studied. Soil samples (n=475) were collected from a large part of the Amhara Region of Ethiopia, where there is widespread Zn deficiency. Zinc status was quantified by measuring several fractions, including the pseudo-total (aqua regia digestion; ZnTot), available (DTPA (diethylenetriamine pentaacetate) extractable; ZnDTPA), soluble (dissolved in 0.01 M Ca(NO3); ZnSoln) and isotopically exchangeable Zn, using the enriched stable Zn isotope 70Zn (ZnE). Soil geochemical properties were assessed for their influence on Zn lability and solubility. A parameterized geochemical assemblage model (Windermere Humic Aqueous Model – WHAM) was also employed to predict the solid phase fractionation of Zn in tropical soils rather than using sequential chemical extractions. ZnTot ranged from 14.1 to 291 mg kg−1 (median = 100 mg kg−1), whereas ZnDTPA in the majority of soil samples was less than 0.5 mg kg−1, indicating widespread phyto-available Zn deficiency in these soils. The labile fraction of Zn in soil (ZnE as % ZnTot) was low, with median and mean values of 4.7 % and 8.0 %, respectively. Labile Zn partitioning between the solid and the solution phases of soil was highly pH dependent, where 94 % of the variation in the partitioning coefficient of 70Zn was explained by soil pH. Similarly, 86 % of the variation in ZnSoln was explained by soil pH. Zinc distribution between adsorbed ZnE and ZnSoln was controlled by pH. Notably, Zn isotopic exchangeability increased with soil pH. This contrasts with literature on contaminated and urban soils and may arise from covarying factors, such as contrasting soil clay mineralogy across the pH range of the soils used in the current study. These results could be used to improve agronomic interventions to tackle Zn deficiency in SSA.

Vitamin B12 status is a risk factor for bone fractures among vegans

Several studies consistently showed vegans having a higher risk of bone fractures compared to individuals from other diet groups. While researchers have focused on several factors as possible explanation of these findings, both dietary (e.g. calcium) and non-dietary (e.g. weight/BMI status), the widespread inadequate vitamin B12 (B12) status among vegans as a risk factor for bone fractures has not received adequate scrutiny. The detrimental impact of inadequate B12 status on bone tissue is both direct, via the impairment of the insulin-like growth hormone 1 and taurine synthesis, and indirect, induced through its hyperhomocysteinemic effect, via at least the following mechanisms: 1) reducing bone mineral content and density by accumulating in the extracellular matrix, 2) reducing osteoblasts and increasing osteoclasts function, 3) reducing blood flow to bone tissue, 4) inducing apoptosis via the reactive oxygen-species-mediated mitochondrial pathway, and 5) obstructing the formation of collagen cross-links, impeding lyslyl oxidase, and hampering insolubility of fibrils. Considering the widespread B12 deficiency prevalence among vegans, its role in bone fracture risk should not be overlooked.

Injury report quality in cases of gender-based violence in the province of Pontevedra

IntroductionGender violence is a health problem with legal consequences. Health professionals must notify these cases to the judicial authority through injury reports. The aim of this study was to analyse the quality of injury reports in gender-based violence cases, assessing whether the recommendations of health protocols are being followed. Material and methodsA retrospective study in a sample of 474 documents issued in cases with suspicion of gender-based violence was carried out. A scale was developed and applied to assess their quality. ResultsMost of the mandatory reporting documents were of medium quality. In 90% of cases data referring to medical staff, women and primary health care were reflected. Likewise, gender violence and the type of violence were specified in 80%. The most widespread deficiencies related to the history of abuse, which were only incorporated in 15% and reference to whether the patient came alone or accompanied in 9%. In addition, more than 72% of documents had abbreviations. The best injury reports were made in primary care facilities. ConclusionsThe quality of injury reports is related to the structure of documents and their origin, highlighting the importance of having a standard document, as well as the need to improve training and awareness of health professionals.

The challenges and future development of animal welfare education in the UK

AbstractAt present, UK schools are not required to teach children about animal welfare. This undoubtedly contributes to widespread deficiencies in knowledge, and misconceptions about animals’ needs, likes, and dislikes. Aware of the issues at hand, animal welfare organisations create their own materials for teachers to use, and/or deliver educational programmes directly to children and young people. As the design, content, processes and outcomes associated with these interventions are rarely documented publicly or systematically evaluated, there is little evidence to guide the development of animal welfare education. A three-stage online Delphi study was used to identify who current interventions target, what delivery methods are being used, and how expert practitioners describe priorities and challenges in the field. Thirty-one experts participated in Round 1, with 84% of the sample (n = 26) also taking part in Round 2. Qualitative analysis revealed passionate accounts about the far-reaching potential of educating children about animals. However, we also identified ambiguities and tensions that could thwart the future development of effective animal welfare education. Alongside the production of a web-based framework and evidence-based toolkit to support practitioners, findings will be used to encourage animal welfare professionals to work towards producing shared terminology, definitions, and outcomes’ frameworks; focusing on positive education and the idea of harm as opposed to cruelty. This should facilitate collaboration with schoolteachers and education policymakers to assess the ways in which animal welfare might be successfully incorporated within formal education in the future. These data suggest many potential avenues for inclusion, although a holistic approach emphasising the links between humans, animals and the environment, within the context of young people's recent activism and contemporary health, societal and environmental issues, may be most successful.

Surveillance Review System to Track Progress Towards Polio Eradication in the Horn of Africa.

BackgroundThe risk for importation and reintroduction wild poliovirus in areas that have been cleared of the wild poliovirus in the Horn of Africa will remain if the surveillance systems are weak and porous.MethodsConsequently, the Horn of Africa Polio Coordinating Office in Nairobi, together with partners conducted surveillance reviews for some of the countries in the Horn of Africa, especially Ethiopia, Kenya and Somalia to identify gaps in the polio surveillance and provided recommendations for improved surveillance. Structured questionnaires collected information about acute flaccid paralysis (AFP) surveillance resources, training, data monitoring, and supervision at provincial, district, and health facility levels. Other information collected included resource availability, management and monitoring of AFP surveillance.ResultsThe result revealed that although AFP surveillance systems were well established in these countries, a number of gaps and constraints existed. Widespread deficiencies and inefficient resource flow systems were observed and reported at all levels. There were also deficiencies related to provider knowledge, funding, training, and supervision, and were particularly evident at the health facility level. These weaknesses were corroborated with the sustained transmission of polioviruses in the region, where the surveillance systems were not sensitive enough to pick the viruses.ConclusionThe review teams made useful recommendations that led to strengthening of the surveillance systems in these countries, including the formation and use of village polio volunteers in the south and central zones of Somalia, where security was heavily compromised and surveillance officers lacked regular access to the communities.

Hair Se Is a Sensitive Biomarker to Monitor the Effects of Se Supplementation in Elderly.

It is rapidly increasing to have selenium (Se) supplementation for urban elderly population in China since they are facing a widespread deficiency daily Se intake. However, until now, there is no low-cost, non-invasive, rapid, and reliable method to monitor the health improvement or risk for elderly Se-supplemented population in China. The present cross-sectional study (229 participants with older than 55 years old) performed in Beijing, China, revealed that the Se concentrations of non-supplementer users (n = 27) were 55 ± 23 μg/L in urine, 139.9 ± 102.3 μg/L in serum, and 487.6 ± 158.7 μg/kg in hair. But a significant increase on hair Se concentrations (615.4 ± 238.8 μg/kg) was observed for Se supplementer users (n = 202) (p < 0.05); there were no significant statistical differences in serum and urine between the Se-supplemented (n = 202) and Se non-supplemented groups (n = 27). This indicated the hair Se levels could be a more sensitive biomarker for Se-supplemented elderly population. Participants who consumed Se supplements for 7-12 months had the highest Se status based on hair and serum Se concentrations (p < 0.05). The present study also revealed that most elderly adults in Beijing just need to supplement 50 μg Se per day to achieve Se plateau status. Furthermore, hair Se levels were positively related with triglycerides/TG levels (p < 0.05) but not body mass index/BMI, total cholesterol/TC, and low-density lipoprotein cholesterol/LDL, implicating Se supplementation for Se sufficiency baseline in elderly population in Beijing likely posed health risk, especially on TG because of excessive Se oxidation stress. An ongoing monitoring of Se status via hair is still warranted to prevent future Se deficiency or excess in China.