The effective functioning of vapor chambers depends on the phase change of the working fluid at the wick surface. Given the prevalent role of vapor chambers in thermal management in the electronics industry, it is critical to study the boiling characteristics and thermal performance of vapor chambers, as well as the effect of heat source conditions. In this work, to observe phase change at the wick surface, the visualization confined chamber with wick (VCCW) is proposed and fabricated, which features a side window and a 2 mm thick wick sintered with aluminum powders. The working fluid used is acetone. The heat source is designed in three different sizes to heat the VCCW in either the middle or right position. The experimental results show that the boiling curve is divided into four stages. In the stage Ⅰ, the boiling curve is linear, and the visualization results reveal that the phase change phenomenon on the wick surface is evaporation. The Ⅱ stage is defined as ONB (Onset of Nucleate Boiling) for the vapor chamber evaporator surface. The boiling curve shows a turning, and bubbles were observed to appear and spread by visualization. In the Ⅲ and Ⅳ stages, the boiling curve remains linear. The stable nucleate boiling and intermittent local dryout is observed before and after the DNB (Departure from Nucleate Boiling). The slope of the boiling curve increases as the size of the heat source enlarges, which contributes to greater superheat and evaporation of the working fluid at smaller heat fluxes. Moreover, the position and size of the heat sources affect the ONB and DNB due to heat diffusion and capillary-driven supply of fluid.