Whooping cough, despite the fact that the disease has long been known, still remains a problem for all countries. Cough attacks can cause not only physical discomfort to the patient, but also a significant negative psycho-emotional load. Existing drug therapy to date does not solve all the problems in the treatment of whooping cough. The aim of our study was to conduct a literature review of pertussis treatment and evaluate the efficacy of inhaled corticosteroids in adult patients with moderate to severe disease.Material and methods. Guidelines for the treatment of whooping cough were studied, and 26 medical records of inpatients with the diagnosis of “Pertussis” were analysed. Conclusion. Antibiotic therapy is a mandatory component of treatment. The effectiveness of inhaled corticosteroids in adult patients with moderate to severe whooping cough has been established.