Whole-body Vibration Research Articles

Effects of whole-body vibration exercise on physical function in patients with chronic kidney disease: a systematic review and meta-analysis

BackgroundThe current state of knowledge regarding the efficacy of whole-body vibration (WBV) training for individuals with chronic kidney disease (CKD) is limited. To address this gap, the present study seeks to undertake a comprehensive systematic review and meta-analysis of clinical trials to evaluate the impact of WBV on physical function and quality of life outcomes in CKD patients.MethodsA systematic search was performed on the PubMed, Embase, Web of Science, and Scopus databases from inception to March 2023 and updated in June 2023. The inclusion criteria comprised randomized controlled studies, quasi-experimental studies, and single-arm trials that evaluated the impact of WBV on physical function, encompassing cardiopulmonary fitness, muscle strength, mobility, and balance, in CKD patients. Adverse events that were included in the study reports were recorded. The pooled evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method.ResultsNine studies were identified, of which seven were included in the meta-analysis. The results of the meta-analysis indicated a statistically significant improvement in upper (mean difference: 3.45 kg; 95% confidence interval 1.61 to 5.29) and lower (standardized mean difference: 0.34, 95% confidence interval 0.08 to 0.59) extremity muscle strength in patients with CKD who underwent WBV training compared to baseline (low-level evidence). Furthermore, WBV training favored improved cardiorespiratory fitness, mobility, and balance function, but no statistical difference was observed. The impact of WBV training on quality of life in patients with CKD requires further validation. Notably, only one adverse event (nausea) was reported in the included studies.ConclusionsWBV has demonstrated efficacy and feasibility in enhancing muscle strength among patients with CKD. However, further investigation is warranted to determine its potential for improving cardiorespiratory adaptations, mobility, balance function, and quality of life. Additionally, future research should prioritize comprehensive reporting of WBV protocols to establish an optimal training regimen for the CKD population.

Investigation of a semi-active suspension system for high-speed trains based on magnetorheological isolator with negative stiffness characteristics

As the operation speed of high-speed train increases, trains with fixed suspension stiffness will encounter dramatical vibrations, especially when its lateral resonance occurs. This greatly affects the ride comfort and safety of the trains. Based on this motivation, a novel stiffness variable suspension system using magnetorheological elastomer (MRE) isolator with negative stiffness is proposed. The controllable stiffness can make the train avoid lateral resonance while the negative stiffness characteristics can provide an actuating force similar to the active control, which further improve the vibration attenuation performance of the suspension. The new MRE isolator was firstly fabricated and tested to verify its stiffness variability, especially negative stiffness characteristics. Four different suspension systems were then tested on a 6-DOF vibration platform for the performance comparison. The experimental results show that this new semi-active lateral suspension system has improved vibration attenuation performance than the passive system and the traditional MRE isolation system without negative stiffness. The vibration attenuation performance of the new suspension system is even comparable to that of some of the existing active suspensions while avoiding the disadvantages of the active control.

Assessing the anti-inflammatory effects of whole-body vibration: a meta-analysis based on pre-clinical and clinical evidences.

Whole-body vibration (WBV) is a commonly used physical exercise for disease prevention and rehabilitation. Recent studies indicated the beneficial mechanism of WBV may be associated with its anti-inflammatory potential, however, its regulatory roles on different inflammatory mediators remained controversial. The aim of this study was to perform a meta-analysis to re-confirm the effects of WBV exercise on various inflammatory factors. The PubMed, EMBASE and Cochrane Library databases were searched up to September 2023 to collect all articles comparing WBV with control (or post-pre trials). The effect size was expressed as the standardized mean difference (SMD) and 95% confidence intervals (CI). A total of 31 eligible studies were included, including 14 pre-clinical and 17 clinical studies. The meta-analysis of pre-clinical studies showed that compared with the control group, WBV exercise could significantly reduce the level of IL-6 (SMD: -1.03, 95% CI: -1.93, -0.13), TNF-α (SMD: -1.36, 95% CI: -2.54, -0.17) (for disease subgroup), IL-1β (SMD: -2.20, 95% CI: -3.24, -1.15), IFN-γ (SMD: -1.91, 95% CI: -2.71, -1.12), IL-4 (SMD: -0.71, 95% CI: -1.39, -0.03) and IL-17 (SMD: -1.32, 95% CI: -2.05, -0.59) overall. Pooling of clinical studies revealed WBV exercise significantly reduced the level of TNF-α (WBV vs control: SMD: -1.11, 95% CI: -2.16, -0.06; post vs pre: SMD: -1.29, 95% CI: -1.91, -0.67), CRP (SMD: -3.59, 95% CI: -6.36, -0.82, P = 0.011) and enhanced the level of IL-10 (WBV vs control: SMD: 2.90, 95% CI: 1.10, 4.71; post vs pre: SMD: 1.75, 95% CI: 0.64, 2.87) and IL-6 (SMD: 0.91, 95% CI: 0.31, 1.52) (healthy subgroup). WBV may be an effective prevention and rehabilitation tool for inflammatory diseases.

Effects of whole-body vibration on chronic ankle instability: a systematic review.

Chronic ankle instability (CAI) is one of the most common sports injuries, and whole-body vibration (WBV) training has been used lately as a potential rehabilitation modality for these patients. The authors conducted a systematic review and meta-analysis to assess whether WBV training positively affects patients with CAI. The authors systematically searched four databases, including MEDLINE (PubMed), Scopus, Web of Science, and Cochrane Central Register of Controlled Trials, for randomized and non-randomized trials evaluating the effects of WBV on individuals with CAI. The authors used Cochrane RoB2 to assess the risk of bias in randomized trials. A meta-analysis was conducted if three or more studies measured the same outcome. Effect estimates were pooled using a random-effects model. Results were retrieved from seven articles encompassing 288 participants who had CAI. The reach distance of the Star Excursion Balance Test (SEBT) was regarded as the study's main finding. The authors saw a significant training effect on certain planes of motion on dynamic balance. The findings showed that the post-intervention measurements in the WBV group compared to control groups showed improvements in the posterolateral, posteromedial, and medial directions, respectively. There were also promising results on improvements in muscle activity, strength, and proprioception sense measurements with a great diversity in the reported parameters. The authors observed a significant WBV training effect on dynamic balance over posterolateral, posteromedial, and medial reach distances. These findings suggest future studies on the effects of WBV on muscle activity, strength, and proprioception in addition to dynamic and static balance.

Therapeutic effects of whole-body vibration on postmenopausal women with osteoporosis: a systematic review and meta-analysis.

The objective of this study was to assess the efficacy of whole-body vibration (WBV) on bone mineral density (BMD), pain levels, and body composition in postmenopausal women with osteoporosis (PMOP). Relevant studies were retrieved from the PubMed, EMBASE, Web of science, CENTRAL, and PEDro databases. Thirteen randomized controlled trials with 783 patients were enrolled. The meta-analysis results showed that WBV can significantly increase lumbar spine BMD (WMD=0.018; 95%CI: 0.004 to 0.032; P=0.011), femoral neck BMD (WMD=0.005, 95%CI: 0.001 to 0.011, P=0.0493), and reduce pain degree (WMD=-0.786; 95%CI: -1.300 to -0.272; P=0.0027) in PMOP, but has no significant effect on patients' muscle mass (WMD=0.547; 95%CI: -1.104 to 2.199; P=0.5158) as well as fat mass (WMD=0.530; 95%CI: -2.389 to 3.448; P=0.7222). To conclude, WBV showed the potential to provide positive benefits in improving BMD and relieving pain of PMOP.

Associations between muscle quality and whole-body vibration exercise-induced changes in plasma hypoxanthine following an oral glucose load in healthy male subjects.

Blood levels of hypoxanthine (HX) have been suggested as potential biomarkers associated with intramuscular metabolic dynamics in response to exercise. This pilot randomized crossover trial (UMIN000036520) aimed to investigate the changes in plasma HX after whole-body vibration exercise (WBVE) and their relationships with body composition and muscle-related parameters, enrolling eighteen healthy male volunteers. In the WBVE-alone intervention, the study subjects performed 20-min of WBVE. In the OGTT → WBVE intervention, a 75-g oral glucose load (OGL) was administered 30 min prior to the start of the WBVE intervention. Blood samples were collected before the start and 10 min after the end of WBVE in both interventions. WBVE resulted in a significant increase in plasma HX levels, which was accompanied by increased blood ammonia, pyruvic acid, and lactic acid levels. The HX increase following WBVE was suppressed by prior OGL. In the WBVE-alone intervention, there were no significant correlations between the post-WBVE changes in plasma HX (ΔHX) levels and any of the clinical parameters. On the other hand, in the OGTT → WBVE intervention, ΔHX showed significant negative correlations with muscle mass (ρ = -0.62, p = 0.01), strength (ρ = -0.71, p = 0.005), and muscle quality (ρ = -0.81, p = 0.0007) in the legs. In conclusion, these findings suggest possible associations between post-WBVE increases in plasma HX levels and muscle status, particularly under the glucose-supplemented condition. The measurement of plasma HX concentrations following WBVE may have clinical applications in the identification of high-risk populations for sarcopenia.

Effects of progessive vs. constant protocol whole-body vibration on muscle activation, pain, disability and functional performance in non-specific chronic low back pain patients: a randomized clinical trial.

Non-specific chronic low back pain (NSCLBP) is a prevalent condition causing significant disability and functional impairment. Whole-body vibration exercise (WBVE) has emerged as a new treatment method, but additional research is necessary to determine the optimal parameters of WBVE that would be beneficial for patients experiencing chronic low back pain (CLBP). This study aims to investigate the effects of two type of WBVE (constant vs progressive) on pain, disability, functional performance, and muscle activity in patients with NSCLBP. Thirty-two individuals diagnosed with chronic low back pain (CLBP) without any specific causes were enrolled and randomly assigned to one of two intervention groups: a constant/fixed protocol WBVE group or a progressive protocol WBVE group. Participants underwent WBVE sessions for around 30 min, thrice weekly over a period of 8 weeks. Primary outcomes assessed included pain intensity, functional disability, functional performance, and electromyographic activity of core musculature, measured at baseline and upon completion of the intervention period. Temporal changes of each outcome variable across different periods and between groups were measured with repeated measures 2×2 mixed ANOVA. Further, the paired t-test was performed to compare pre- and post-treatment values within each group. Significant improvements were observed in both the constant and progressive WBVE protocol groups. Pain intensity decreased by 64.2% (p<0.001) in the constant group and by 61.1% (p<0.001) in the progressive group. Functional disability decreased by 48.1% (p<0.001) in the constant group and by 53.3% (p<0.001) in the progressive group. Functional performance improved by 16.5% (p<0.001) in the constant group and by 16.9% (p<0.001) in the progressive group. Electromyography (EMG) demonstrated significant improvements across all measured variables except % maximum voluntary isometric contraction (%MVIC) of external obliques (EO) in both intervention groups with time (p<0.001). There was no statistically significant difference in the magnitude of improvement between the constant and progressive WBVE protocols (p>0.05), indicating both modalities' effectiveness in ameliorating CLBP symptoms and associated functional impairments. The study demonstrates that both progressive and constant WBVE protocols are equally effective in reducing pain and disability in NSCLBP patients. These findings support the inclusion of progressive WBVE in clinical practice, offering a flexible treatment option that can be tailored to individual patient needs, ensuring both tolerability and effectiveness. This contributes valuable evidence towards optimizing WBVE protocols for managing NSCLBP.

A157: The Effect of Whole-Body Vibration Therapy on the Motor Abilities of Patients with Sarcopenia

Purpose: The highly morbid condition known as sarcopenia affects middle-aged and elderly people and is characterized by a progressive loss of whole-body muscle mass accelerated by aging. It is also accompanied by a decline in muscle strength and physiological function. These weakening functions manifest as impaired physical movement, increased risk of falls, disability, lower quality of life, and even death. Sarcopenia is progressively emerging as a new public health issue in China with a quickly aging population, making it vital to investigate effective exercise therapies for sarcopenic patients. Methods: Sixty sarcopenic patients (aged 60-75) from a local hospital in northeast China participated in the study. They were randomly divided into a test group and a control group, with 30 patients in each. The test group underwent a 40-minute whole-body vibration training session for 12 weeks, five times a week, while the control group kept regular routines. Data were collected at the end of the experiment, including muscle strength, muscle mass, muscle function, gait speed, berg balance scale (BBS), five sit-to-stand test (FTSST), activities of daily living (ADL), fall risk assessment scale (FRA), and Sarcopenia Quality of Life Scale (SarQoL) scores. Results: The 12-week whole-body vibration training intervention resulted in a significantly higher value of muscular strength, muscle mass, and muscle function among the test group compared to the control group. The former achieved substantially higher SPPB, ADL, FTSST, and BBS scores than the latter (p &lt; 0.01). With much lower FRA scores and significantly better SarQoL ratings compared to baseline, the test group also significantly outperformed the control group in terms of fall risk and quality of life (p &lt; 0.01). Conclusion: With whole-body vibration training, people with sarcopenia can increase their skeletal muscle strength, considerably enhance their motor function, lower their risk of falls and accidents, and generally improve their quality of life. Whole-body vibration training is worthy of therapeutic use since it is both feasible and practical.

A focus on exercise prescription and assessment for a safe return to sport participation following a patellar tendon reconstruction in a soccer player

Purpose: The aim of this study was to analyse a 6-month kinesiological intervention after patellar tendon reconstruction. The kinetics, kinematics, and neuromuscular differences between operated (OL) and non-operated limbs (N-OL) were examined over time in a soccer player. Methods: The assessment took place at three months (T0) and nine months (T1) after the reconstruction. This comprised an assessment of the range of motion (ROM), gait analysis through angle-angle diagrams, postural control, neuromuscular assessment during whole-body vibration (WBV), and unilateral-bilateral maximal voluntary isometric contractions (MVICs) synchronised with surface electromyography (sEMG). Results: The angle-angle diagrams at T1 show that the area and perimeter of the N-OL and OL diagrams increased, especially the area and perimeter of the knee-ankle diagram in OL. Furthermore, the postural control at T1 indicated an increase in different conditions. The root mean square (RMS) of sEMGRMS obtained during WBV revealed a significant alteration in the neuromuscular patterns in the OL at T1. The increase in the vastus lateralis (VL) and lateral gastrocnemius (LG) activities was accompanied by a decrease in the biceps femoris (BF) and tibialis anterior (TA). The peak of force and the rate of force development during MVICs showed a slight difference between OL and N-OL at T1. Furthermore, sEMGRMS activity synchronised with MVICs showed a slight difference between the OL and N-OL in the extensors (VL, VM, and RF) and flexors (BF) muscles at T1. Conclusions: The kinetic, kinematic, and neuromuscular variables have shown improvements at T1 compared to T0. Anyway, a 6-month individualised kinesiological intervention, following a patellar tendon reconstruction, reveals that minor alterations in the neuromuscular pattern remain in the OL. These results help kinesiologists manage the functional recovery after patellar tendon reconstruction.

The effect of whole-body vibration therapy on mechanical nociceptive thresholds and postural stability in horses with thoracolumbar pain

ObjectivesTo determine the effects of WBV on thoracolumbar pain, multifidus muscle CSA, and postural stability in horses with thoracolumbar pain AnimalsTen horses with thoracolumbar pain ProceduresHorses received WBV for 30 minutes once daily, 5 days per week, for 30 days. Mechanical nociceptive thresholds (MNTs) at T13, T18, L3, L6, S2 were assessed on days 0, 1, 14, and 30. Ultrasound of the multifidus muscle cross-section area (CSA) and postural sway (2 conditions: flat square stance and standing on proprioceptive balance pads) were assessed on days 0 and 30. ResultsMNTs were significantly lower than baseline on day 1 (P<0.001) and day 14 (P=0.004). MNTs were significantly higher than baseline on day 30 (P<0.001). Mediolateral accelerations were significantly lower on day 30 compared to day 0 (P< 0.001). Multifidus muscle cross-sectional area was significantly increased on day 30 compared to day 0 (P = 0.0005). Clinical relevanceWBV may exacerbate pain in horses with thoracolumbar pain when used short-term (<14 days). Long-term use (4 weeks) is needed to improve thoracolumbar pain. Four weeks of once daily WBV is sufficient to improve postural stability and increase multifidus muscle CSA.

Effect of whole-body vibration on insulin resistance in females with polycystic ovarian syndrome: A randomized controlled trial

Effect of whole-body vibration on insulin resistance in females with polycystic ovarian syndrome: A randomized controlled trial

Experiment and optimisation analysis of whole-body vibration among tractor drivers: a comprehensive study

Experiment and optimisation analysis of whole-body vibration among tractor drivers: a comprehensive study

Efficacy of Combining Whole-body Vibration Training and Closed Kinetic Chain Exercises in Early Knee Osteoarthritis: A Preliminary Study.

We aimed to conduct a preliminary evaluation of the effectiveness of integrating whole-body vibration training (WBVT) into conventional closed kinetic chain (CKC) exercises as an intervention strategy for early knee osteoarthritis (KOA). : This non-randomized comparative study conducted at an orthopedic clinic involved 53 patients (with Kellgren-Lawrence grades 1-2); 37 patients received only physical therapy (CKC group), and 16 patients received both physical therapy and WBVT (WBVT group). The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) subscale score for pain, and the secondary outcomes were the WOMAC subscale score for physical function and muscle-strength assessments [isometric knee extension strength and the 30-second chair-stand test (CS-30) score]. Propensity score matching (PSM) was used to adjust for bias between the control and intervention groups. : After PSM adjustment, 13 patients were selected from each group. The WBVT group showed a significant improvement in the WOMAC pain score (d=1.16, P=0.007) and a significant increase in the CS-30 score (d=0.81, P=0.049). However, for the WOMAC physical function score, the between-group difference remained statistically insignificant (d=0.59, P=0.146). : WBVT may be effective in reducing the pain of early KOA. WBVT is a non-invasive and convenient method, underscoring its potential as a novel therapeutic option.

Effect of Whole-Body Vibration on Bone Quality in Breast-Cancer Metastatic Bone

Effect of Whole-Body Vibration on Bone Quality in Breast-Cancer Metastatic Bone

Lipidomics Profiling of the Linoleic Acid Metabolites After Whole-Body Vibration in Humans.

Bioactive lipids have been identified as dynamic signaling lipid mediators (LMs). These fats have the ability to activate responses and control bodily functions either directly or indirectly. Linoleic Acid (LA) and Alpha Linoleic Acid (ALA) are types of omega 3 fatty acids that possess inflammatory properties and promote resolution of inflammation either through their own actions or through their metabolites known as oxylipins. In this chapter, we provide an explanation of a method that combines chromatography with tandem mass spectroscopy (LC MS/MS) to identify and measure all the metabolites derived from LA and ALA. Additionally, we employed the described methodology to analyze human serum samples obtained before and after whole-body vibration exercise training. The results indicated an increase in some of the LA and ALA LMs that have beneficial effects in regulating the cardiovascular system.

Multi-investigation of the Ameliorative Effects of Whole-body Vibration on Osteoporotic Bone

Multi-investigation of the Ameliorative Effects of Whole-body Vibration on Osteoporotic Bone

Adoption of artificial neural network technique to optimise the whole-body vibration

Adoption of artificial neural network technique to optimise the whole-body vibration

Effect of whole-body vibration stimulation on plasma soluble TNF receptors in elderly with sarcopenia: a randomized controlled trial.

Sarcopenia is a pathology resulting from a progressive and severe loss of muscle mass, strength, and function in the course of aging, which has deleterious consequences on quality of life. Among the most widespread studies on the issue are those focused on the effect of different types of physical exercise on patients with sarcopenia. This randomized controlled study aimed to compare the effects of a whole-body vibration exercise (WBV) session on the inflammatory parameters of non-sarcopenic (NSG, n=22) and sarcopenic elderly (SG, n=22). NSG and SG participants were randomly divided into two protocols: intervention (squat with WBV) and control (squat without WBV). After a one-week washout period, participants switched protocols, so that everyone performed both protocols. Body composition was assessed by dual-energy radiological absorptiometry (DXA) and function through the six-minute walk test (6MWD) and Short Physical Performance Battery (SPPB). Plasma soluble tumor necrosis factor receptors (sTNFR) were determined by enzyme-linked immunosorbent assay (ELISA) and measured before and immediately after each protocol. After exercise with WBV, there was an increase in sTNFR2 levels in the NSG (P<0.01; d=-0.69 (-1.30; -0.08) and SG (P<0.01, d=-0.95 (-1.57; -0.32) groups. In conclusion, an acute session of WBV influenced sTNFr2 levels, with sarcopenic individuals showing a greater effect. This suggested that WBV had a more pronounced impact on sTNFr2 in those with loss of muscle strength and/or physical performance. Additionally, WBV is gaining recognition as an efficient strategy for those with persistent health issues.

Dynamic characteristics of a compliant seat coupled with the human body and a manikin during the exposure to the whole-body vibration: Effect of the polyurethane foam, the track position, and the measurement location

Purpose Transmissibility is used to assess dynamic responses of the occupant-seat system, and most studies have exclusively assessed the transmissibility from the floor to the cushion or the backrest surface with the human body. Methods In this investigation, the vertical vibration transmitted from the floor to six specific locations both on the seat surface and the frame when the seat was fixed on three positions on the track was examined utilizing an SAE J826 manikin and 12 male adults (0.25 to 20 Hz) for a duration of 120 seconds at three vibration amplitudes. Results The transmissibility from the floor to the headrest frame, the cushion surface, the headrest surface, the seat back frame, and the seat back surface all exhibited a principal peak frequency within 4-5 Hz. With the exception of the cushion frame, the principal peak frequency and the peak transmissibility in transmissibilities to all positions decreased with increasing vibration amplitude, indicating the non-linearity within the occupant-seat system. It was also found modifying seat track positions minimally affected the seat transmissibility to either the surface or the frame of the seat. Conclusions Polyurethane foam amplified vibration at peak frequency, simultaneously enhancing static sitting comfort and reducing the vertical vibration transmission above peak frequency.

Evaluating physical therapy interventions for pediatric developmental disorders: Enhancing motor skill

Objective: To evaluate the efficacy of specific physical therapy interventions, including Metaverse Physical Therapy, Nintendo Wii-integrated therapy, Whole-Body Vibration training, Segmental trunk and head control training, Ride-on car training, swimming programs, structured bimanual skill training, and running interventions in enhancing motor skills in children with pediatric developmental disorders. Methodology: A systematic review of randomized controlled trials (RCTs) and longitudinal studies published from 2013 to 2023 was conducted. Studies that compared the effects of innovative physical therapy interventions such as metaverse physical therapy, virtual reality-enhanced treatments, and Nintendo Wii-integrated therapy, and traditional physical therapies on children with developmental disorders were included. Primary outcomes assessed included improvements in motor skills, cognitive functions, and social interactions. Results: The review identified significant improvements in motor function across various interventions. Innovations like metaverse physical therapy and virtual reality-enhanced treatments showed additional benefits in engagement and motivation. While all interventions generally improved motor skills, those incorporating advanced technologies and integrative approaches also positively impacted cognitive and social development, although to varying degrees. Conclusion: Physical therapy, particularly when integrating new technologies and holistic approaches, is crucial for improving overall development in children with developmental disorders. The review highlights the need for personalized, multifaceted therapy plans that address not only physical but also cognitive and social needs to optimize outcomes.