To investigate the Effect of Date of Sowing and Wheat varieties on Yield Attributes, Yield and the profitability of wheat. A field experiment was conducted at the Students’ Instructional Farm of Agronomy, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur, Utter Pradesh (UP) during Rabi 2021-22 growing seasons. A split plot design with four replications was used in this study. The experimental treatments were date of sowing as main factor (D1-15th November, D2-30th November, D3-10th December) and wheat varieties as sub-factor (V1-DBW-187, V2-K-1006, V3-HD-2967). The result of this study showed the interaction effect of Date of Sowing and Varieties of wheat were non-significant. In the different date of sowing, the 15th November sown crop resulted in significantly higher spike length (10.67 cm), spike weight (3.147g), number of grains spike-1 (53.55), 1000- grain weight (42.06 g), grain yield (52.81 q ha-1), gross income (INR ha-1 118837.667), net income (INR ha-1 49087.66) as well as B:C ratio (1.7), of wheat as compared to 30th November, 10th December.. Among wheat varieties, HD-2967 resulted the highest values of Yield Attributes viz. spike length (10.44 cm), number of grains spike-1 (52.41), 1000- grain weight (40.85 g), Yield viz. grain yield (51.38 q ha-1) and Profitability viz. gross income (INR ha-1 115612.66), net income (INR ha-1 45862.66) as well as B:C ratio (1.65). The greatest grain yield was obtained with HD-2967 variety sowed on 15th November. Thus, it is possible to maximize the Yield attributes, Yield and the Profitability of wheat by sowing HD-2967 variety on 15th November.