The objective of this article is to evaluate unified fractional integrals and derivative formulas involving the incomplete $$\tau $$ -hypergeometric function. These integrals and derivatives are further applied in proving theorems on Marichev–Saigo–Maeda operators of fractional integration and differentiation. The results are expressed in terms of the generalized Gauss hypergeometric functions (Fox–Wright function). Corresponding assertions in terms of Saigo, Erdelyi–Kober, Riemann–Liouville, and Weyl type of fractional integrals and derivatives are presented. Also, we develop their composition formula by applying the Beta and Laplace transforms. Further, we point out also their relevance.