To reveal the characteristics and environmental indications for the combination of the grain size and magnetic susceptibility of coastal sediments, we provided a necessary basis for further study on their genetic mechanisms. Based on the data of grain size and magnetic susceptibility of the 36.10 m long core 07SR01 sediments in the Xiyang tidal channel of western South Yellow Sea, we analyzed their variations and correlations and further revealed their environmental indications and corresponding regional sedimentary evolution via the combination of the aforementioned analysis results, the reinterpretation results of the sedimentary sequence and the age of core 07SR01 and shallow seismic profiles, and the findings of climate and glacial–eustatic cycles during Late Quaternary. The three stages of the sedimentary evolution of the Xiyang tidal channel between marine isotope stage (MIS) 7 and MIS 5 were summarized as follows: First is the stage of marginal bank and riverbed developments in the tidal estuary under a relatively high sea level and strong hydrodynamic conditions during MIS 7 (core section: 36.10–26.65 m). The sediments deposited in this stage were mainly affected by the paleo-Changjiang River and characterized by a coarse grain size (mean: 4.02 Φ) and relatively high magnetic susceptibilities (mean: 27.06 × 10−8 m3·kg−1), with small fluctuations which were strongly and positively correlated with the sand component. Second is the stage dominated by fluviolacustrine and littoral environments with the weak hydrodynamics during MIS 6–5, in which the climate changed from cold and dry to warm and humid as the sea level rose after a drop (core section: 26.65–15.77 m). The sediments deposited in this stage were characterized by a fine grain size (mean: 5.27 Φ) and low magnetic susceptibilities with minor variations (mean: 10.83 × 10−8 m3·kg−1) which were weakly and positively correlated with the coarse silt component. Third is the stage of delta front in the tidal estuary with a relatively high sea level and strong hydrodynamics during MIS 5 (core section: 15.77–0 m). The sediments deposited in this stage were strongly influenced by the paleo-Yellow River and characterized by a relatively coarse grain size (mean: 4.86 Φ), and high magnetic susceptibilities (mean: 37.15 × 10−8 m3·kg−1) with large fluctuations which were weakly and positively correlated with the sand and coarse silt components.