The increase in the demand for increased crop yield with minimal impact on the soil fertility has lead to innovation in crop cultivation practices. Integrated Nutrient Management is the practice of maintaining the fertility of the soil as well as the ensuring the continuous supply of nutrients to the soil at an optimum level for sustaining the desired productivity by optimizing the benefits of organic, inorganic and biological sources in an integrated manner. Sericulture is basically an agro-based industry that involves cultivation of host plants and the rearing of silkworms for the production of cocoon which in turn yields raw silk. Good quality mulberry leaves are very importance source of food for the silk worms as it indirectly determines the quality of the silk produced. One such technique to enhance the quality of mulberry leaves produced is the practice of Integrated Nutrient Management. In this study, Cow dung, Vermicompost and NPK was practiced on the field after I, II, and III pruning of mulberry crop during the time period of 2018 – 2019 at field No.1 of Western block, Department of Sericulture, Demonstration cum Training Centre, V.M Chatram, Tirunelveli to evaluate the efficiency of Integrated Nutrient Management practices on growth and yields parameters of mulberry. It was found from the study that the Cow dung and vermicompost when applied to the field displayed a better effect over the parameters of growth such as height, no of branches, leaves, leaf yield and stem girth, etc in comparison to the commercially available NPK. It can be concluded from the study that Integrated Nutrient Management practices when applied for plant cultivation can provide better yield without affecting the native properties of the soil.