West Ethiopia Research Articles

Rabies suspected human cases in and around Jimma zone, south west Ethiopia

Rabies, a viral disease affecting warm-blooded animals, poses a significant public health concern in Ethiopia, particularly concerning human transmission through dogs. To shed light on the status of suspected rabies cases in humans in the Jimma zone and surrounding areas, a retrospective study was conducted at the Jimma Town Health Center from November 2021 to May 2022. The area's rabies status had been unknown since 2012. From 2019 to 2022, a total of 2,223 suspected human rabies cases were recorded at the Health Center, with Jimma town and Xiro Afeta districts of Jimma zone reporting the highest (62%) and lowest (0.3%) numbers, respectively. Of these cases, 96.9% (2,155) resulted from dog bites, with children under 15 years old constituting the majority (52.8%) of victims. Town areas accounted for 66.8% (1,378) of the cases. Significantly variable occurrences were observed in relation to religious category, season, source of exposure, affected body part, and districts within the Jimma zone (P=0.000). The main challenges identified included an increase in stray dog populations, the absence of control centers, lack of awareness about pre-exposure vaccination for owned dogs, a scarcity of rabies vaccine in local veterinary services, and the unavailability of post-exposure prophylaxis at district health centers. Addressing these issues through awareness campaigns for dog owners on pre-exposure vaccination and ensuring the provision of post-exposure prophylaxis to all district health centers is crucial for controlling and preventing rabies in the study area. Asian J. Med. Biol. Res. 2023, 9 (4), 126-133

Elucidating sole application of farmyard manure and blended NPSB fertilizer effects on soil properties at Bench Shako and West Omo zone, South West Ethiopia

Soil nutrient depletion is the main problem in Ethiopia for agriculture sector. Comparison of organic and inorganic source of fertilizer is needed for soil physicochemical properties improvement. Hence, the current study was investigated to investigate the sole application of farmyard manure and blended NPSB fertilizer on soil properties. For this investigation, farm yard manure at three level (0,5, and 10 t ha-1) and NPSB at four level (0, 50, 100, and 150 kg ha-1). All collected data were analysed by GenStat software. Sole application of farm yard manure significantly improves soil bulk density ((1.23 gcm3 to 1.11 gcm3 at kuja Guraferda, and 2.22 gcm3 to 1.12 g/cm3 deka Maenit-Goldia) and soil moisture content from 12.14 % to 33.79 % at kuja, and 11.88 % to 36.01%at deka). More over application of farm yard manure improve soil pH (6.15) organic carbon (6.20 mg/kg) available phosphorus (18.94 mg/kg, total nitrogen (0.32), sulfur (18.27), boron, exchangeable base, cation exchange capacity, micronutrients (copper, manganese & zinc). Application of NPSB fertilizer improves only, total nitrogen, available phosphorus, sulfur and boron. Application of Farm yard manure significantly improve soil physicochemical properties than NPSB mineral fertilizer in comparison. Therefore, application of farm yard manure is more important than mineral NPSB fertilizer for sustainable soil physical and chemical properties improvement from soil management aspect. Thus, application farmyard manure at 10 t/ha is recommended for the studied soil at West Omo zone Maenit-Goldia district, Deka kebele, and Bench-Skako zone, Guraferda district at Koyi kebele, south west people regional state, South West Ethiopia.

Predictors of Stunting among 6–35 Months Old Children in Assosa Zone, Northwest Ethiopia: Unmatched Case–Control Study

Background. In 2020, globally, 149.2 million under 5 years old children were stunted. In Africa, 61.4 million and 79 million under 5 years old children in Asia were also stunted in 2020. Stunting is a major public health problem in Ethiopia, where more than 5.5 million children under 5 years old are stunted. Stunting has irreversible and intergenerational health consequences, including impaired cognitive and physical growth, poor learning capacity, and reduced work productivity. Efforts to end stunting need comprehensive and context identification of risk factors. For this reason, this study aims to identify the predictors of stunting among children 6–35 months of age in Northwest Ethiopia. Method. A community-based, unmatched case–control study was employed in the Assosa zone, Benishangul Gumuz, west Ethiopia. A multistage and simple random sampling technique was used to select the study participants. Data were collected through interviewer-administered questionnaires using validated structured questionnaires and anthropometric measurements. Data were entered into Epidata version 3.1 and exported to SPSS 25.0 statistical software for analysis. Bivariate and multivariate analyses were computed. Finally, an adjusted odds ratio (AOR) with a 95% confidence interval (CI) was used to identify independent predictors of stunting using a multivariable logistic regression model. Result. The study included 544 mother–child pairs (181 cases and 363 controls), with a 100% response rate. The majority of the mothers, 85 (47.0%) in the case and 153 (42.1%) in the control group, were in the 25- to 29-year-old age group. This study revealed that mothers who had no formal education (AOR = 2.5, 95% CI (1.436, 4.180)), short maternal height (<150 cm) (AOR = 4.25, 95% CI (2.714, 6.663)), exclusive breastfeeding for less than 6 months (AOR = 3.16, 95% CI (1.97, 5.10)), minimum dietary diversity (AOR = 3.09, 95% CI (1.97, 5.01)), additional food during pregnancy (AOR = 2.26, 95% CI (1.44, 3.5)) and food security (AOR = 3.08, 95% CI (1.79, 5.26)) were found to be independently statistically associated with child stunting. Conclusion and Recommendation. This study revealed that the predictors of stunting among children aged 6–35 months were multifactorial, which calls for an integrated and multisectoral intervention to reduce or eliminate stunting. Mothers’ factors, educational status, additional food during pregnancy, and child feeding, including dietary diversity and exclusive breastfeeding, were modifiable predictors of child stunting. Therefore, we call for promoting mothers’ education, creating awareness among mothers about optimum infant and young child feeding, specifically exclusive breastfeeding, and promoting mothers’ practices of dietary diversity feeding.

Antimicrobial-Resistance Profile of Helicobacter pylori, Obtained from Endoscopic Patients in Bahir Dar, North West Ethiopia.

Antimicrobial resistance for Helicobacter pylori infection is a highly emerging problem throughout the world to treat gastric-associated diseases. People living in developing countries are more likely to acquire a Helicobacter pylori infection and less likely to gate treatment after infection due to poverty. Therefore, the current study was aimed at determining the magnitude and antibiotic-resistance profile of Helicobacter pylori isolated from patients who underwent endoscopic examination. A cross-sectional study was conducted from January to May 2019 at endoscopy service-providing health facilities that are found in Bahir Dar, Ethiopia (Gamby teaching general hospital, Kidane Mihret specialty higher clinic, and Eyasta specialty higher clinic). Data were collected using a pretested, structured questionnaire. Antibiotic susceptibility of Helicobacter pylori isolates from gastric biopsies was determined. Data were analyzed using SPSS version 23. The 17.8% proportion of Helicobacter pylori was isolated from 135 endoscopy-examined patients (24/135). The majority of isolates (71% of 17/24) were from males, while only 29% of 7/24) were from females. Antimicrobial-resistance of Helicobacter pylori was high to all commonly prescribed antibiotics: amoxicillin and metronidazole (91.7%), clarithromycin and ciprofloxacin (66.7% each), and tetracycline (37.5%). Helicobacter pylori isolates from the current study participants were rather low in number. But the highest antibiotic-resistance profile of Helicobacter pylori was observed. Therefore, these findings alarmingly indicate that routine antimicrobial susceptibility testing against Helicobacter pylori isolates is crucial for better patient management.

Adherence to Lifestyle Modification Practices and Its Associated Factors Among Hypertensive Patients in Bahir Dar City Hospitals, North West Ethiopia.

Globally, hypertension affects 1.4 billion adults, accounting for 31% of the world population. The prevention and control of hypertension is not addressed only by pharmacological management. Even though the prevalence of uncontrolled hypertension and its complications is increasing every day, Adherence to lifestyle modification practice among diagnosed hypertensive individuals is low for a number of reasons. The study aims to assess adherence to lifestyle modification practices and associated factors among hypertensive patients at Bahir Dar city hospitals, in North West Ethiopia. An institutional-based cross-sectional study design was conducted at Bahir Dar city from October 30 to November 30, 2022. A stratified sampling technique was used. For the data quality pre-test was done, the questionnaire was checked for completion, the assumption of binary logistic regression (VIF 1.8 and no outlier), and model fit using the Hosmer and Lemeshow's test was checked. Binary logistic and multivariate logistic regression were used to find significant variables after the data were entered into EpiInfo and analyzed using SPSS version 23. The overall adherence to lifestyle modification practices was about 32.4%. From the independent factors, above secondary educational status (AOR = 0.201 95% CI (0.081-0.499)), good knowledge (AOR = 3.323 95% CI (1.79-6.168)), good self-efficacy (AOR = 3.553 95% CI (1.91-6.613)), good social support (AOR = 8.339 95% CI (4.251-16.357)), and good patient-physician relationship (AOR = 2.424 95% CI (1.309-4.490)) were statistically significant predictors of adherence to lifestyle modification practices. Only one-third of the participants had adhered to the recommended lifestyle modifications. Educational status, knowledge, self-efficacy, social support, and patient-physician relationships were significant factors. Healthcare organizations should develop programs to raise hypertension patients' awareness and degree of self-efficacy that aid in adherence to advised lifestyle changes.

Diversity of Tree Species Regeneration in Natural Gaps of Kafa Moist Afromontane Forest, South West Ethiopia Peoples` Region, Ethiopia

Diversity of Tree Species Regeneration in Natural Gaps of Kafa Moist Afromontane Forest, South West Ethiopia Peoples` Region, Ethiopia

Nutrition, stress, and healthcare use during pregnancy are associated with low birth weight: evidence from a case-control study in West Ethiopia.

Low Birth Weight (LBW) remains a major public health concern globally, especially in lower and middle-income countries. In Ethiopia in general and in the study area in particular there is limited evidence regarding maternal factors associated with low birth weight. This study aimed to identify the maternal factors associated with low birth weight among neonates born in public health facilities in the west Wollega zone, West Ethiopia. We used a case-control study design and selected participant mothers with a newborn using the delivery database from three public hospitals and five health centers, between March 2022 and April 2022. Cases were identified using a newborn birth weight of <2,500 grams. Controls were identified using a newborn birth weight of ≥2,500 grams. An interviewer-administered structured questionnaire and chart review were used for data collection. Model fitness was assessed by Hosmer and Lemenshow goodness-of-fit test, including multi-collinearity checks. Candidate predictor variables were selected (using a value of p <0.25 in bivariable logistic regression models) for multivariable logistic regression to quantify the association between independent variables and LBW, expressed using Odds Ratios (OR) with a 95% Confidence Interval (CI). Mean and Standard Deviation (SD), all such values. A total of 324 mothers with their newborns (81 cases and 243 controls) were eligible for inclusion. The mean age of participants was 27.9 years (SD 6.4) in cases and 25 years (SD 3.9) in controls. Mean birth weight was 2,128 grams (SD 1,697) in cases and 2,988 grams (SD 378) in controls. In multivariable logistic regression analysis, lack of nutritional counseling (OR = 2.4; 95%CI: 1.24-4.72), maternal middle upper arm circumference of <23 cm (OR = 3.1; 95%CI: 1.64-5.91), maternal stress during pregnancy (OR = 2.8; 95% CI:1.23-6.36), and antenatal follow up less than four visits (OR = 2.8; 95% CI: 1.12-6.82) were independently associated with LBW. In this study, lack of nutritional counseling, maternal undernutrition, maternal stress during pregnancy, and antenatal follow-up visits less than recommended were associated with LBW. Special attention should be given to promoting antenatal care and counseling mothers on nutrition and relaxation to prevent stress during pregnancy.

Prevalence and factors associated with neonatal acute respiratory distress syndrome among neonates admitted to the neonatal intensive care units of Gurage zone public hospital, South West Ethiopia.

Respiratory distress syndrome (RDS) is the leading cause of respiratory failure and death of a neonate in today's world, especially in developing countries like Ethiopia. We used an institutional-based cross-sectional study in the selected hospitals of the Gurage zone admitted from June 2019 to June 2021. The data were collected using a structured questionnaire. Data were entered into Epi data 3.1 and exported to SPSS version 25 for analysis. The prevalence of respiratory distress syndrome (RDS) in the study area was 45.1%. The odds of RDS in neonates from mothers with gestational age between 35 &37 were 3.99 times higher compared to term gestation. The odds of RDS among neonates with jaundice and sepsis are 4.33- and 1.92-times higher odds compared to their counterparts. The odds of RDS in neonates born via Caesarean section were 1.7 times higher compared with those delivered via spontaneous and instrumental delivery. RDS was also higher in neonates born to mothers <20 years of age and >=35 years old. the prevalence of RDS in the study area was high. Thus, healthcare providers should act on those factors with appropriate follow-up for early detection of the problem and prevent the risk.

Antenatal depression and associated factors among pregnant women attending antenatal care at public health facilities in the Gida Ayana district, Oromia Region, West Ethiopia, in 2022.

Though antenatal depression (AND) has a risk of maternal and fetal morbidity and mortality, it is a neglected component of pregnancy care in Ethiopia. Research evidence is compulsory in different parts of the country to alleviate this problem. Thus, this study was needed to assess antenatal depression and its associated factors, which can help antenatal care (ANC) providers and program coordinators focus on the mental health of pregnant mothers. This study aimed to assess antenatal depression and associated factors among pregnant women attending ANC at public health facilities in the Gida Ayana district, Oromia Region, West Ethiopia, in 2022. A facility-based cross-sectional study was conducted among 370 pregnant women attending ANC at public health facilities. Systematic random sampling techniques were used to select study participants. A standard (validated) tool, the Edinburgh Postnatal Depression Scale, was also used to assess antenatal depression. The collected data were coded, entered into Epi-data software version 4.6, and analyzed by SPSS version 23. Multivariable logistic regression analyses were used to identify associated factors with a p-value <0.05. In this study, the prevalence of antenatal depression was 62 (16.8%; 95% CI: 13, 20.5). Being single in marital status (AOR = 3, 95% CI: 1.5, 6.2), having an unplanned pregnancy (AOR = 2.7, 95% CI: 1.45, 5.1), and having partner conflict (AOR = 3.49, 95% CI: 1.79, 6.8) were the factors associated with antenatal depression. About one in five pregnant women has antenatal depression. Being single, having an unplanned pregnancy, and having a dissatisfied relationship with a sexual partner were the factors associated with antenatal depression. Therefore, women or partners are expected to plan pregnancy, and the dissemination of health information related to an unplanned pregnancy needs to be intensified by health providers. The partner ought to avoid conflict during the pregnancy, and healthcare providers or families are needed to support the single or widowed pregnant women. Further prospective cohort studies are needed to ascertain the effect of antenatal depression on fetal-maternal outcomes.

Cultural competence and associated factors among nurses working in public health institutions in the Assosa zone, Benishangul Gumuz regional state, Ethiopia, 2022

BackgroundCultural competence is one of the principal foundations of clinical nursing. In Ethiopia, nurses in nursing care still focus more on physical needs, the healing process, and treatment and less on the cultural aspects of the patient.ObjectiveThis study aims to assess the cultural competence and associated factors among nurses working in public health institutions found in the Assosa Zone, West Ethiopia, in 2022.MethodsAn institution-based cross-sectional study design was conducted on 362 nurses who were selected by simple random sampling. Data was collected using a structured, self-administered English version of the Nurse Cultural Competence Scale Questionnaire for Nurses. The data were entered into Epi Data version 3.1 and exported to SPSS version 25. Linear regression analysis was used to identify factors statistically significantly associated with the cultural competence of nurses at a p-value < 0.05.ResultOverall The mean score of cultural competence of participants was 113 (CI, 111.7–115.7), with a mean item score of 3.2 (CI, 3.15–3.26).Nurse-to-patient ratio (B;.93, CI;.59_1.3), experience with previously working in a primary hospital than the current health institution (B; -11.1, CI; -18_-4.2), and experience with previously working in a health center than the current health institution (B; -11.5, C;-18.5_-4.8), being diploma education level (B; -23.2, CL;-32_-14.8), being BSC education level (B;-20.3, CI;-28_-12.3), and the presence of a feedback system in a health facility (B; 13.5, CI; 9.5_17.5) were identified as predicted factors of cultural competences.ConclusionThe overall mean score of the cultural competencies of the participants was moderate. To improve the cultural competence of nurses, it is typically necessary to provide educational opportunities to raise their educational level and establish a feedback system in all health institutions across the nation.

Internet addiction and associated factors among undergraduate students of Jimma University; Jimma, South West Ethiopia, institutional based cross-sectional study

BackgroundInternet addiction affects cognitive function, has a harmful impact on students’ academic performance, and increases their risk of experiencing psychological crises.ObjectivesExamining the prevalence of internet addiction and its contributing factors among regular undergraduate students at Jimma University in south-west Ethiopia.MethodsAn institutional-based cross-sectional study was conducted among study participants between August 1 and August 30, 2021. A total of 772 Participants were involved in the study using a multistage random sampling technique. Data was collected using pretested and structured questionnaires with self-administered techniques. The Young Internet Addiction Test (YIAT) was used to measure internet addiction. The data was entered into the computer using Epi Data version 4.6, and then it was exported to the Statistical Package for Social Science (SPSS) version 25 for analysis. The association between each independent variable and the outcome variable was examined using bivariate analysis. Variables with a p-value of less than 0.25 in bivariate analysis were included in the multivariate logistic regression model to determine how each independent variable affected the outcome variable.ResultThe prevalence of internet addiction among study participants was 53.6% (95% Confidence Interval (CI)) (49.99%, 57.15%). Findings from multivariate logistic regression analysis suggested a variety of related factors had significant associations with internet addiction. Being dissatisfied with a major study, having a cumulative grade point average of a promoted grade report, using the internet for entertainment, using the internet for Facebook, using the internet for telegram, depression, social anxiety, and poor social support.ConclusionThis study revealed a comparatively high frequency of internet addiction among study participants. Internet addiction has been linked to psychosocial, academic, and purpose-related aspects of internet use. As a result, incorporating stakeholders’ efforts to improve the identified variables would be a helpful start toward lowering this high incidence.

The Effect of Family Planning Education on Knowledge, Attitude and Practice Toward Family Planning Methods Among Married Couples in Kersa and Goma Districts of Jimma Zone, South West Ethiopia.

Individuals with accurate knowledge that goes beyond knowing a few contraceptive methods, such as knowledge of fertility, benefits, and contraceptive side effects, are more likely to use and less likely to discontinue using family planning. The aim of the study was to determine the effect of family planning education on knowledge, attitude, and practice towards family planning among married couples in Jimma Zone, Ethiopia. A quasi-experimental study was done on 766 married couples sampled using a random sampling technique and analyzed using SPSS 23.0. The significance of differences in mean knowledge and attitude between control and experimental couples was measured using the non-parametric 2-independent sample analysis (P < 0.05). The comparison of knowledge score means and significance of their differences between control and experimental women was found to be significant at the posttest (P = 0.001; r = 0.045). Similarly, the experimental men's knowledge score means and their difference was significant at posttest (P = 0.001, r = 0.26). With respect to a comparison of mean score of attitude and the significance of their difference between control and experimental women at posttest was significant with (P < 0.001; r = 0.13). Similarly, the comparison of the male partners in the control and experimental groups was significant at posttest (P = 0.001; r = 0.12). At the posttest, the proportion of experimental couples using each contraceptive method relatively increased, with a shift to relatively effective ones. Two hundred and ninety five (77.6%) of the control and 318 (83.5%) of the experimental men reported supporting their wives in the use of contraceptives, showing more improvement among the experimental men than the control group. Along with routine counseling, a well-structured behavioral model-based family planning education is required for effective and continuous use of contraceptives.

Polymerase chain reaction-positivity and predictors for SARS-CoV-2 infection among diagnosed cases' in North West Ethiopia.

The lack of sophisticated diagnosing equipment for polymerase chain reaction (PCR) during the incidence of variant types of COVID-19 underestimates the morbidity and mortality patterns of this pandemic. Thus, this study aimed to estimate seropositive and confirmatory predictors for COVID-19 suspected and tested cases through polymerase chain reaction (RT-PCR) in two diagnosing. A facility-based descriptive cross-sectional study was employed among COVID-19 suspected cases from January 2, 2022, to June 9, 2022. The data were collected both using a structured interviewees and nasopharyngeal (NP) swabs. The nasal swab (NS) was analyzed in the laboratory for RNA detection of the virus using PCR. The collected data were entered into Epi Data version 4.2 and then exported to STATA (SE) version R-14 software for further analysis. multivariable logistic regression was used to assess the associated risk. A total of 285 suspected cases have participated in this study. The overall mean (±SD) age of the participants was 37.5 (±18.5) years. The majority, 174 (61.1%) of the tested groups were symptomatic when diagnosed. The positivity of RT-PCR for suspected and COVID-19 diagnosed cases were confirmed in 62/285 (21.75%). In multivariable analysis, they were aged 26-50 years (adjusted odds ratio [AOR] = 4.2, 95% confidence interval [CI] = 1.5-10.75), had comorbidity (AOR = 5.8; 95% CI = 2.1-12.2), and cigarette smokers (AOR = 13.5; 95% CI = 5.3-36.6) were significantly associated with developing COVID-19 infection. More than two in every nine suspected cases were positive RT-PCR tests, and the infectivity of COVID-19 was significantly associated with age 25-50 years, comorbidities, and cigarette smoking. The deployment of high-quality diagnostic kits like RT-PCR is crucial for the early detection and risk stratification of suspected cases.

Pertussis outbreak investigation in south Gondar zone, Northwest, Ethiopia

Aims: Pertussis, also known as whooping cough, is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. Though vaccines are the most successful and cost-effective way of preventing pertussis, the outbreak of pertussis is still high in the Amhara region. The study aimed to investigate the pertussis infection in Simada district, North West Ethiopia, 2021. Methods: A community-based active surveillance was conducted in the Simada district from December 3/2020 to January 05/2021. A total of 43 cases was identified using the modified Centers for Disease Control and Prevention (CDC) pertussis diagnosis criteria and line lists. The collected data were entered into the Epi-data (Epidemiological Data) version 3.1 and analyzed using R version 4.03 software and descriptive statistics computed. Results: A total of 43 cases were identified with an overall attack rate of 7.1 per 1000 population. All complicated cases occurred in children under four years of age. The most affected groups were females. There was an interrupted routine immunization service in the cluster at the health post-level to associate vaccination coverage with the occurrence of a pertussis outbreak. The outbreak was reported after three days of the occurrence of more transmission from person to person. Conclusion: The outbreak of pertussis was high and the children were suffering. It is advisable to build capacity, consolidate routine vaccination services, and enhancing the vaccine cold chain management system, surveillance and early treatment of infected patients to control the expansion of pertussis.

Evaluation of breeding objectives, breeding practices and reproductive performance of indigenous dairy cows in selected districts of Kaffa Zone, South West Ethiopia.

Breeding objectives are designed to achieve targeted dairy cow production goals, which can be affected by production type, farmer preferences, environmental factors and genetic factors individually or in combination. Breeding practices, such as both controlled and uncontrolled, and artificial insemination (AI) are the tools used to obtain the desired breeding objectives. The lower reproductive performance of indigenous dairy cows affects the total milk production and calf crops that are produced during their lifetime. Designing appropriate breeding objectives and breeding practices can improve the reproductive performance of dairy cows and their overall production performance. The current study was conducted with the objective of evaluating the breeding, practices and performance of indigenous dairy cattle in the south western part of Ethiopia. The districts of Gesha and Chena were purposefully chosen. The study design for the 384 household surveys was a cross-sectional survey with a simple random sample approach. Data analysis was carried out by MS-Excel (2010) and the general linear model procedure of SAS of 2008. The current study revealed that methods of breeding were predominantly natural-controlled mating, followed by natural-uncontrolled mating and AI in descending order. Breeding objectives were input function, output function, sociocultural and economic functions and assets and security functions in decreasing order of rank. Reproduction performance indexes of indigenous dairy cows age at first service (3.72±0.05 years), age at first calving (AFC) (4.71±0.07 years), calving interval (CI) (1.58±0.03 years), days open (DO) (4.26±0.11 months), services per conception in natural mating (1.4±0.08) and AI (2.73±0.14), age of bull at maturity (4.17±0.74 years), interoestrus interval (23.18±0.61 days), calves crop (7.53±0.22) and the life span of indigenous dairy cow (11.94±0.26 years) were significant (p<0.01) between two districts, whereas the values of age of bull at maturity and number of services per conception in natural mating were significant (p<0.05) between districts. Using AI and major reproduction performances, such as AFC, CI and DO of indigenous dairy cows in the study area, were very low. Therefore, concerned bodies should intervene to improve reproduction performance through the utilization of AI techniques, with the integration of forage development activities and improvements in livestock health care.

Time to Recovery from COVID-19 and Its Predictors in Patients Hospitalized at Tibebe Ghion Specialized Hospital Care and Treatment Center, A Retrospective Follow-Up Study, North West Ethiopia.

Since the end of 2019, the world has been facing a new coronavirus disease 19 (COVID-19), which is considered a global pandemic. COVID-19 is considered a major public health burden due to the uncontrolled morbidity and mortality of the global community. The World Health Organization estimates the recovery time as 2 weeks for patients with mild infection and 3 to 6 weeks for those with serious illnesses. The recovery time and its predictors are not well studied in Ethiopia yet. Therefore, the aim of this study was to estimate time to recovery from COVID-19 and its predictors among COVID-19 patients admitted to Tibebe Ghion Specialized Hospital care and treatment center, North West Ethiopia. An institution-based retrospective follow-up study was conducted among 452 COVID-19 patients admitted to Tibebe Ghion Specialized Hospital from March 2020 to September 2021. Simple random sampling using a table of random number generators was used to select study units. Data entry and analysis were performed using EpiData 3.1 and Stata version 14, respectively. Bivariable and multivariable Cox proportional hazard analyses were used to identify predictors of recovery time. An AHR at a 5% level of significance was used to identify significant predictors. : Among 452 COVID-19 patients, 437 (88%) were recovered, with a median recovery time of 9 days. Recovery time was significantly related to age (AHR = 0.98; 95% CI = 0.97, 0.99), oxygen saturation (AHR = 0.42; 95% CI = 0.31, 0.56), shortness of breath (AHR = 0.65; 95% CI = 0.47, 0.85), disease severity (moderate (AHR = 0.63; 95% CI = 0.47, 0.85) and severe (AHR = 0.32; 95% CI = 0.22, 0.47)), and comorbidities (AHR = 0.67; 95% CI = 0.53, 0.84). Conclusions and recommendations: The overall median recovery time was 9 days. Older age, low oxygen saturation, shortness of breath, disease severity (moderate and severe), history of comorbidities, and high-level of WBC were predictors of delayed recovery time. On the other hand, corticosteroid use significantly shortens the median recovery time of COVID-19 patients. Thus, patients presented with older age, low oxygen saturation, shortness of breath, moderate and severe COVID-19 disease, comorbidities, and increased WBC need to be closely monitoring and followed up by healthcare providers. In addition, there should be special attention during the administration of corticosteroid.

Reproductive phenology of &lt;i&gt;Milicia excelsa&lt;/i&gt;, &lt;i&gt;Antiaris toxicaria&lt;/i&gt;, and &lt;i&gt;Pouteria adolfi-friedericii&lt;/i&gt; in South West Ethiopia

Deforestation and degradation of natural forests pose a challenge for the forest sector in Ethiopia. Gathering scientific data on the reproductive biology of selected timber species has now become important to develop seed production areas and establish forest management regimes. In this regard, this study is aimed at determining the reproductive phenology of three indigenous tree species. The time of leafing, flowering, and fruiting in the three indigenous timber tree species has been recorded for three years in South West Ethiopia. This study was conducted in natural forests of the Benchi-Maji zone (Debub Bench district). We selected three prioritized species, Milicia excelsa, Antiaris toxicaria, and Pouteria adolfi-friedericii, based on the severity of their depletion and relative timber values in the area and in the country at large. Over 20 reproductively healthy, mature, and average mother trees 10 cm wide in diameter at breast height and with easily visible crowns, located at a distance of 100 m from one another, were selected out of each species and marked with marking ink. We conducted continuous observations and recorded data on leafing, flowering, and fruiting every 15 days (twice every month). The data was then analyzed using descriptive statistics. The result of this study indicates that the actual season when the seeds of Milicia excelsa are available for collection is once a year, from January to February. The results also showed that, for Antiaris toxicaria, the fruiting time is seasonal, and seeds become available for collection from early January up to the end of February. The fruiting time or the actual season when seeds of Pouteria adolfi-friedericii become available for collection is from May to June. Low-cost technologies (to establish seed production areas and domesticate the species) are recommended to be used for seed/seedling acquisition and distribution and preferable to reduce the destruction of the selected indigenous tree species.

Variability and association among tuber yield and yield related traits of potato (Solanum tuberosum L.) genotypes in Debre markos district, north west Ethiopia

Twenty five potato genotypes were tested 5*5 simple lattice design in Debremarkos, north western Ethiopia, during the main rainy season of 2019. The objectives of the study were to assess the nature and magnitude of variability, to estimate the genotypic and phenotypic association among characters and to cluster genotypes based on their genetic similarity and divergence. The analysis of variance showed the presence of significant (P < 0.05) differences among genotypes for all trait. The phenotypic coefficient of variation (PCV) ranged from 8.8 to 58.70% and genotypic coefficient of variation (GCV) from 5.62 to 35.17%. The values for heritability in broad sense and genetic advance as percent of mean ranged from 22.98 to 91.25% and 5.55–69.17% respectively. Tuber yield per hectare showed a positive and highly significant (P < 0.01) correlation with marketable tuber yield both at the genotypic and phenotypic levels. Tuber yield showed positive, negative and significant (P < 0.05) correlation with plant height, average number of tuber, average tuber weight and small tuber size at genotypic and phenotypic levels. Cluster analysis had revealed that the 25 genotypes were grouped in 5 distinct clusters. Maximum and minimum average intra cluster D2 was obtained in cluster III (D2 = 5.69) and cluster IV (D2 = 2.63) respectively. This shows that there is a maximum genetic recombination is expected from the hybridization of the parents selected from divergent cluster groups. Principal component analysis showed that the first seven principal components accounted for 84.65% for the observed variations among potato genotypes.

Factors Influencing Blood Donation Practice Among Health Care Providers of Public Hospitals in Bahir Dar City, North West Ethiopia: A Case Control Study.

Blood donation is a technique in which blood is collected from a healthy individual for transfusion to someone else. WHO estimates that it is necessary to donate blood to 2% to 3% of the country's population to meet blood needs. However, blood donation remains challenging in developing countries. This study aimed to identify factors influencing blood donation practices among healthcare providers in public hospitals in Bahir Dar City. This institution-based unmatched case-control study was conducted in Bahir Dar City Public Hospitals from May 01 to May 25, 2022. Total sample size was 491 (123 cases and 368 controls) and then the study subject was selected by using simple random sampling technic and collect data through self-administered questionnaire. Bi-variable and multi-variable binary logistic regression analyses were used to determine the association between dependent and independent variables. Finally, the results are presented in charts and tables, and the AOR and CI are reported. Statistical significance was set at P < 0.05. Fear of anemia (adjusted odds ratio (AOR): 0.02; 95% CI 0.007-0.078), lack of opportunity (AOR: 0.42; 95% CI 0.22-0.83), lack of time (AOR: 0.03; 95% CI, 0.005-0.199), profession (AOR: 0.15; 95% CI, 0.05-0.42), aware of free medical checkup (AOR: 31.79; 95% CI 13.13-76.94), willingness to donate blood (AOR: 5.09; 95% CI 2.25-11.50), blood group type (AOR: 5.67; 95% CI 1.42-22.68), and higher work experience (AOR: 7.99; 95% CI 2.59-24.67) were found to be significantly associated with blood donation practice. This study revealed that multiple factors influenced the practice of blood donation among healthcare providers. Therefore, access to blood donation areas and emphasizing the importance of donor blood donation are important for facilitating blood donation.

Prevalence, drug-susceptibility pattern and associated factors of Mycobacterium tuberculosis infection among prisoners in western Arsi zonal prisons, Oromia, South West Ethiopia

ObjectivesEach year, tuberculosis (TB) in prisons is a major worldwide health concern that results in millions of diseases. It is particularly prevalent in low socio-economic countries like Ethiopia because of the poverty, overcrowding, starvation, lack of access to basic healthcare services, and high prevalence of HIV infection in these countries. MethodsA cross-sectional study with 259 prisoners was carried out in the western Arsi zonal prison from November to January 2021. The sputum samples were taken from suspected TB patients and evaluated using the Gene Xpert Mycobacterium tuberculosis/rifampcine test. Line probe assay was used to assess the molecular drug susceptibility of isolates from positive sputum. A bivariate and multivariate logistic regression was analyzed using SPSS version 24 packages. Odds ratio (OR) and corresponding 95% CI were used to quantify the degrees of association between target potential risk factors and Mycobacterium tuberculosis positivity. P-value of less than 0.05 was considered statistically significant. ResultsThe prevalence of undiagnosed pulmonary TB (PTB) verified positive cases was 5.4% (95% CI 2.7, 8.5) out of 259 research participants that were recruited in this study. One (0.38%) occurrence of mono-drug resistance to isoniazid was found among them. In this study, variables that were significantly linked with PTB positive were age ≥30 years, smoking (adjusted OR [AOR] = 0.087, 95% CI = 0.01-0.93, P = 0.043), body mass index 18.5 kg/m2, cough duration 4 weeks (AOR = 0.03, 95% CI = 0.1-0.13 P = 0.001), and coughing before incarceration (AOR = 6.2, 95% CI = 3.6-10.59, P = 0.004). ConclusionIn West Arsi zonal prisons, PTB and mono-drug resistance for isoniazid were found to be more common than in the general population.