Fluent Aphasia Research Articles

Regression of Poststroke Aphasia and Concomitant Nonspeech Syndromes Due to Courses of Restorative Therapy Including Intensive Speech Therapy

Objectives. To analyze clinical indicators and fMRI parameters associated with the therapeutic efficacy of courses of complex restorative therapy including intensive speech therapy in various clinical forms and severities of aphasia syndrome. Materials and methods. A total of 40 right-handed patients with aphasia syndrome were studied three months after disease onset before and after courses of therapy (4.7 weeks) including intensive speech therapy (15 h/week). The efficacy of courses of treatment and cognitive rehabilitation was assessed using changes in measures of neuropsychological, neurological, and neuroimaging investigations before and after patients received treatment. The extents of restoration of speech and nonspeech cognitive functions were evaluated (using a 10-point assessment of cognitive functions addressing changes in focal deficit (NIHSS), and patients’ functional recovery (Barthel index, modified Rankin scale). Neuroimaging methods included structural MRI, fMRI at rest, and the fMRI equivalent of the mismatch negativity (MMN) component of event-related potentials using a sequence of standard and deviant sounds (Russian-language phonemes) to obtain the MMN equivalent. A program written in Python 3.6.0 was used. Results. The greatest efficacy of courses of restorative therapy (≥15% improvement on subtests of the quantitative assessment scale) was seen in 28 cases (70%): 18 patients with initially severe and 10 patients with moderate aphasia (independently of the clinical type of aphasia) and in all 11 patients with isolated sensory aphasia. Regression of sensory aphasia was accompanied by marked activation of the intact speech homologs of the right hemisphere and the appearance of a low-volume, low-intensity activation of the left temporal-parietal area, with a near-normal location. Regardless of the clinical form of aphasia, maximum therapeutic efficacy was associated with reorganization of the speech-related resting neural network, including increases in both intrahemisphere and interhemisphere functional connectivity, with increases in intrahemisphere interactions between the posterior speech zones in the left hemisphere on the background of decreases in their interhemisphere connectivity. Statistically significant improvements in motor and sensory functions were seen in nine patients with moderate contralateral spastic hemiparesis (22%) (p ≤ 0.00), which did not correlate with the level of regression of speech and nonspeech impairments. A minor therapeutic effect was seen in 12 patients (30%) with mild and moderate speech and nonspeech cognitive impairments which did not correlate with any particular clinical form of aphasia. Conclusions. Courses of restorative hospital treatment lasting 4.7 weeks including intensive speech therapy (15 sessions per week) were maximally effective mainly in severe aphasia, as well as in a defined clinical form – isolated sensory aphasia. fMRI data identified a different compensatory reorganization of the neural speech network probably reflecting the features of poststroke neuroplasticity associated with regression of both severe speech impairments and a particular clinical form of aphasia.

Evaluating informative content and global coherence in fluent and non-fluent aphasia.

Discourse analysis is an important component of aphasia assessment because it can provide an insight into functional communication abilities. However, there are many unknowns regarding the levels of discourse breakdowns that occur across aphasia types. The purpose of the current study is to explore the possible differences in discourse-level communication in persons with fluent and non-fluent aphasia during picture description. To examine if persons with fluent and non-fluent aphasia differ on utterance-level discourse measures when evaluating informative content and global coherence. Additionally, to evaluate and compare the types of global coherence violations made by each group. Data from 31 people with aphasia was collected from AphasiaBank, which included 13 people with fluent aphasia and 18 people with non-fluent aphasia. Discourse samples from three picture descriptions were analysed. Discourse outcomes included utterances with new information (UNIs-relevant utterances containing new information) and global coherence (the extent to which each utterance maintained the overall discourse theme). Additionally, seven types of errors were identified to explore the nature of breakdowns in global coherence. People with fluent aphasia produced significantly higher proportions of UNIs and had significantly higher average global coherence ratings than those with non-fluent aphasia. Differences in global coherence violations were identified with people with fluent aphasia producing more non-specific, incorrect and off-topic utterances and people with non-fluent aphasia producing more incomplete utterances. One of the most common global coherence error types in both groups was commentary. Although people with fluent aphasia produced more types of global coherence errors, including incorrect, non-specific and off-topic utterances, the group was still rated significantly higher on utterance relevance and topic maintenance, indicating that the ability to produce a complete utterance plays an important role in some aspects of discourse production. Additionally, these findings provide an insight into potential targets for intervention.

Repetition Tasks for Treatment of Wernicke Aphasia in an Adolescent: Case Study

Repetition Tasks for Treatment of Wernicke Aphasia in an Adolescent: Case Study

Factors Influencing Aphasia Outcome in Patients with Occlusive Stroke

AbstractBackground: Aphasia related to ischemic stroke is a major health problem affecting the quality of life profoundly.Aim of Study: Is to assess factors influencing aphasia outcome in patients with occlusive stroke and the role of functional magnetic resonance imaging in detection the patterns of post-stroke language recovery.Patients and Methods: This was a prospective cohort study done at Neuropsychiatry Department and Center of Psychiatry, Neurology and Neurosurgery, Diagnostic Radiol-ogy, Tanta University, from January 2017 to January 2018. Aphasia Rapid Test (ART) at day 1 and follow-up at day 8 which is a bed side clinical test to assess aphasia severity, Diffusion Tensor Imaging (DTI) and fMRI were done at day 8 to assess aphasia severity. A total of 34 cases were finally included in this study after fulfilling the inclusion and exclusion criteria, 12 patients who had receptive or global aphasia, were not suitable for fMRI, their native language Arabic, age Results: The total number of the studied patients was 34 of them 18 patients (52.9%) were males and 16 patients were females (47.1%). The age of the studied patients ranged from 28-79 years. The older group of patients had severe language disability also those with global aphasia and perisylvian lesion, risk factors as HTN, DM, Cardiac Disease, Dyslipidemia had worse prognosis, those with no reconstruction of the Arcuate Fasiculus in DTI and fMRI data analysis showed negative effect of the site contralateral to lesion.Conclusion: Age was a significant factor with the higher age group had the worst prognosis regarding aphasia. Large lesion sizes and those with damage to strategic language areas had a bad prognosis. fMRI and DTI were the cornerstone of our study and they were a highly reliable tools in the prognosis of language outcome, with those who had activity in the perilesional and bilateral activity (perilesional and contralateral homotopic) in fMRI to have better outcome than those with only contralateral activity, also DTI to delineate the AF and the degree of its integrity and reconstitution.

Do You Understand Me? An Aphasia Assessment Case Study in a Non-Native English Speaker

Abstract Objective We report on the assessment of a non-native, English speaking patient who presented for a comprehensive neuropsychological evaluation following an infarct with associated language deficits. Challenges in assessment and interpretation given language and cultural barriers are discussed. Case Description The patient presented for an evaluation of cognitive and emotional difficulties following a left internal carotid artery infarct. Brain MRI revealed multiple acute infarcts in the left hemisphere, including the left occipital, medial aspect of the left temporal, left frontal, and left parietal lobes. While the patient had lived in the U.S. for 30 years and spoke English fluently for work, he primarily spoke his native language (Tamil). Given the lack of medically certified interpreters in the region along with a lack of culturally sensitive tests, the patient was evaluated in English using English-based tests and norms. Diagnostic Impressions and Outcomes Results were suggestive of a transcortical sensory aphasia. Language comprehension deficits were observed in both oral and written formats, while simple oral expression and repetition remained intact. The lack of normative data that matched the patient’s demographic background in addition to the lack of available samples regarding the patient’s English language functioning prior to the stroke made assessing the severity of deficits challenging. The family’s cultural norms and the patient’s unawareness of his deficits may have resulted in underreporting of the patient’s symptoms to providers. These factors further complicated the selection of appropriate recommendations for short- versus long-term disability. Discussion Specific challenges included an inability to assess the patient in his native language while using culturally-sensitive measures; thus, shedding light on the current clinical need for increasing competency in the assessment of non-native English-speaking patients. Further directions and opportunities are discussed.

Auditory, Phonological, and Semantic Factors in the Recovery From Wernicke’s Aphasia Poststroke: Predictive Value and Implications for Rehabilitation

Background. Understanding the factors that influence language recovery in aphasia is important for improving prognosis and treatment. Chronic comprehension impairments in Wernicke’s aphasia (WA) are associated with impairments in auditory and phonological processing, compounded by semantic and executive difficulties. This study investigated whether the recovery of auditory, phonological, semantic, or executive factors underpins the recovery from WA comprehension impairments by charting changes in the neuropsychological profile from the subacute to the chronic phase. Method. This study used a prospective, longitudinal observational design. Twelve WA participants with superior temporal lobe lesions were recruited 2 months post–stroke onset (2 MPO). Language comprehension was measured alongside a neuropsychological profile of auditory, phonological, and semantic processing and phonological short-term memory and nonverbal reasoning at 3 poststroke time points: 2.5, 5, and 9 MPO. Results. Language comprehension displayed a strong and consistent recovery between 2.5 and 9 MPO. Improvements were also seen for slow auditory temporal processing, phonological short-term memory, and semantic processing but not for rapid auditory temporal, spectrotemporal, and phonological processing. Despite their lack of improvement, rapid auditory temporal processing at 2.5 MPO and phonological processing at 5 MPO predicated comprehension outcomes at 9 MPO. Conclusions. These results indicate that recovery of language comprehension in WA can be predicted from fixed auditory processing in the subacute stage. This suggests that speech comprehension recovery in WA results from reorganization of the remaining language comprehension network to enable the residual speech signal to be processed more efficiently, rather than partial recovery of underlying auditory, phonological, or semantic processing abilities.

Incidence and types of aphasia after first-ever acute stroke in Bengali speakers: age, gender, and educational effect on the type of aphasia

ABSTRACT Background The pattern of post-stroke aphasia in speakers of Bengali language has not previously been reported in the literature. Furthermore, the inter-relationship between age, gender, and level of education and aphasia typology has remained unsettled thus far. Aims To investigate the incidence and type of aphasia in first-ever acute stroke patients who were speakers of Bengali language. Methods & Procedures Bengali version of Western Aphasia Battery was used for language assessment in our study participants. Lesion localization was done by using magnetic resonance imaging(3T) for ischemic stroke (if not contraindicated) and computed tomography for hemorrhagic stroke. Among 515 screened cases of first-ever acute stroke, 208 presented with aphasia. Language assessment was done between 7 and 14 days in all study participants. Outcomes & Results The incidence of post-stroke aphasia in our sample was found at 40.39%. Types of aphasia were – Broca’s (38.5%) followed by global (27.9%); Wernicke’s (12.5%); transcortical motor (9.6%); anomic (4.3%); transcortical sensory (3.8%); isolation (1.9%); and conduction (1.4%). Mean number of years of formal education was significantly higher in fluent aphasia group in comparison with non-fluent group (10.51 years versus 7.01 years, p = 0.003). In logistic regression analysis, location of lesion (posterior perisylvian) (p = 0.007, OR = 5.406, 95% CI, 1.602–18.240) and education (p = 0.044, OR = 1.097, 95% CI, 1.003–1.199) were two independent predictors favoring fluent aphasia. Conclusions Aphasia among post-stroke Bengali patients is quite frequent. The commonest type of aphasia in our sample was Broca’s aphasia. Bengali-speaking people with higher education were more likely to present fluent aphasia.

Semantic Processing in Bilingual Aphasia: Evidence of Language Dependency.

Individuals with aphasia frequently show lexical retrieval deficits due to increased interference of semantically related competitors, a phenomenon that can be observed in tasks such as naming pictures grouped by semantic category. These deficits are explained in terms of impaired semantic control, a set of abilities that are to some extent dependent upon executive control (EC). However, the extent to which semantic control abilities can be affected in a second and non-dominant language has not been extensively explored. Additionally, findings in healthy individuals are inconclusive regarding the degree to which semantic processing is shared between languages. In this study, we explored the effect of brain damage on semantic processing by comparing the performance of bilingual individuals with aphasia on tasks involving semantic control during word production and comprehension. Furthermore, we explored whether semantic deficits are related to domain-general EC deficits. First, we investigated the naming performance of Catalan–Spanish bilinguals with fluent aphasia and age-matched healthy controls on a semantically blocked cyclic naming task in each of their two languages (Catalan and Spanish). This task measured semantic interference in terms of the difference in naming latencies between pictures grouped by the same semantic category or different categories. Second, we explored whether lexical deficits extend to comprehension by testing participants in a word-picture matching task during a mixed language condition. Third, we used a conflict monitoring task to explore the presence of EC deficits in patients with aphasia. We found two main results. First, in both language tasks, bilingual patients’ performances were more affected than those of healthy controls when they performed the task in their non-dominant language. Second, there was a significant correlation between the speed of processing on the EC task and the magnitude of the semantic interference effect exclusively in the non-dominant language. Taken together, these results suggest that lexical retrieval may be selectively impaired in bilinguals within those conditions where semantic competition is higher, i.e.,- in their non-dominant language; this could possibly be explained by an excessive amount of inhibition placed upon this language. Moreover, lexico-semantic impairments seem to be at least somewhat related to conflict monitoring deficits, suggesting a certain degree of overlap between EC and semantic control.

Phonological and phonetic impairment in aphasic speech: an acoustic study of the voice onset time of six French-speaking aphasic patients

ABSTRACTThe aim of the present study is to contribute to the description of the speech production deficits in French-speaking aphasic patients, so as to shed light on their potential phonetic and/or phonological disorders. Acoustic studies of aphasics’ speech productions remain relatively infrequent, especially in French, and when entering into the specifics, often lead to inconsistent results. We conducted a multiple-case study on six aphasic patients, four with non-fluent aphasia and two with fluent aphasia. They were administered a variety of language and neuropsychological tasks, then they participated in a customized non-word repetition task. Acoustic analyses of their speech productions were performed, focussing on VOT as the main acoustic correlate of the voicing contrast for oral stops. Other atypicalities in their productions were also classified. Results showed variable and mainly “mixed” phonetic-phonological impairment profiles that differed from the traditional hypotheses made in the literature about the speech deficits to be expected as a function of type of aphasia. Our results support the use of acoustic analyses in order to complete language examination in aphasic patients but also suggest that the frontier between phonological and phonetic impairment is not clear-cut. These outcomes are better accounted for by theories and models postulating close relationships between the phonological and phonetic levels of processing.

The multiplex structure of the mental lexicon influences picture naming in people with aphasia.

An emerging area of research in cognitive science is the utilization of networks to model the structure and processes of the mental lexicon in healthy and clinical populations, like aphasia. Previous research has focused on only one type of word similarity at a time (e.g., semantic relationships), even though words are multi-faceted. Here, we investigate lexical retrieval in a picture naming task from people with Broca's and Wernicke's aphasia and healthy controls by utilizing a multiplex network structure that accounts for the interplay between multiple semantic and phonological relationships among words in the mental lexicon. Extending upon previous work, we focused on the global network measure of closeness centrality which is known to capture spreading activation, an important process supporting lexical retrieval. We conducted a series of logistic regression models predicting the probability of correct picture naming. We tested whether multiplex closeness centrality was a better predictor of picture naming performance than single-layer closeness centralities, other network measures assessing local and meso-scale structure, psycholinguistic variables and group differences. We also examined production gaps, or the difference between the likelihood of producing a word with the lowest and highest closeness centralities. Our results indicated that multiplex closeness centrality was a significant predictor of picture naming performance, where words with high closeness centrality were more likely to be produced than words with low closeness centrality. Additionally, multiplex closeness centrality outperformed single-layer closeness centralities and other multiplex network measures, and remained a significant predictor after controlling for psycholinguistic variables and group differences. Furthermore, we found that the facilitative effect of closeness centrality was similar for both types of aphasia. Our results underline the importance of integrating multiple measures of word similarities in cognitive language networks for better understanding lexical retrieval in aphasia, with an eye towards future clinical applications.

Analysing coherence of oral discourse among Cantonese speakers in Mainland China with traumatic brain injury and cerebrovascular accident

Purpose: Coherence can reflect subtle language deficits in individuals with traumatic brain injury (TBI) and cerebrovascular accident (CVA). This study aimed at investigating whether global and local coherence in Cantonese-speaking adults with CVA and TBI differ from non-brain-injured (NBI) speakers. Factors contributing to the coherence ratings and impacts of elicitation tasks on coherence were examined.Method: Two clinical groups with fluent aphasia (7 CVA and 11 TBI) and 18 controls matched in age and education, who were Cantonese speakers living in China participated. Language samples of single and sequential picture description and storytelling were elicited, and subsequently analysed on global and local coherence, content sequence, and informativeness.Result: TBI speakers had impaired global and local coherence, while CVA speakers had poor global coherence. Sequence of main events produced by the three groups correlated significantly with global coherence. Attention and visuospatial skills were also significantly related to global coherence in both clinical groups. Finally, impaired language integrity was associated with problems of local coherence.Conclusion: The results were consistent with previous studies. Linguistic deficits of coherence in discourse in the two clinical groups and possible impacts of elicitation tasks on the cognitive demands and coherence ratings were discussed.

Sustained attention failures on a 3-min reaction time task is a sensitive marker of dementia.

The objective of the study is to determine the utility of a simple reaction time task as a marker of general cognitive decline across the frontotemporal lobar degeneration (FTLD) spectrum and in Alzheimer's disease (AD). One hundred and twelve patients presenting with AD or FTLD affecting behaviour (behavioural-variant frontotemporal dementia), language (progressive non fluent aphasia, logopenic progressive aphasia, semantic dementia) or motor function (corticobasal syndrome, progressive supranuclear palsy, frontotemporal dementia-motor neuron disease) and 25 age-matched healthy controls completed the Psychomotor Vigilance Task (PVT), a 3-min reaction time (RT) task. The proportion of lapses (RT > 500ms) was significantly increased in dementia patients compared to healthy controls, except for semantic dementia, and correlated with all cognitive functions except language. Discrimination of individuals (dementia patients versus healthy controls) based on the proportion of lapses yielded the highest classification performance (Area Under the Curve, AUC, 0.90) compared to standard neuropsychological tests. Only the complete and lengthy neuropsychological battery had a higher predictive value (AUC 0.96). The basic ability to sustain attention is fundamental to perform any cognitive task. Lapses, interpreted as momentary shifts in goal-directed processing, can therefore, be used as a marker of general cognitive decline indicative of possible dementia.

Speech and Language Dysfunctions in Patients with Cerebrocortical Disorders Admitted in a Neurosurgical Unit.

Introduction:Speech and language abnormality among brain injury patients are common, especially during the acute stage. The details of same from Andhra Pradesh (AP) state are limited. The present study provides details of speech and language abnormality among brain damage patients, from a tertiary care hospital AP.Materials and Methods:This study was conducted at tertiary care hospital, Nellore, AP. Patients with acute brain damage due to traumatic brain injury (TBI), cerebrovascular accident (CVA), and postoperative cases of brain tumors were selected for the study. Detail of speech and language disturbances was accessed using Western Aphasia Battery. All patients were right-handed and Telugu was their first language.Results:There were totally 38 patients, of them 28 had TBI, 8 patients were postoperative cases of brain tumor, and 2 cases were of CVA. The mean age was 45.6 years. A total of 22 patients were literate. TBI patients with left cerebral hemisphere damage manifested with anomic, conduction, transcortical sensory, global, and Wernicke's aphasia. Four patients of postoperative brain tumor manifested with anomic and transcortical sensory aphasia had left-sided brain damage and mild dysarthria had right-sided brain damage patient. CVA patients had anomic aphasia and subcortical aphasia having right and left cerebral hemisphere damage, respectively.Conclusions:This study reports that acute brain damage due to various causes manifest with speech and language abnormality, especially when the left cerebral hemisphere is involved.

THE STUDY OF LANGUAGE DISORDER OF AN AUTISTIC SAVANT PORTRAYED IN LEVINSON’S RAIN MAN FILM (1988)

ABSTRACT Autistic savant as one of the language disorders can be found in daily life and it also can be portrayed in literary works and films. An autistic savant is a person with autism who has the limitation in most social functions but has cognitive abilities, such as possessing some outstanding memories and computational skills. This research aims to find out the types of language disorder and to find out the dominant type of language disorders found in autistic savant portrayed in Levinson’s Rain Man film. This research used a descriptive method. The data used in this research were the utterances of an autistic savant. The result of this research shows that the type of expressive language disorder was obtained with the occurrence percentage of 67.7% while the receptive language disorder type was obtained by the occurrence percentage of 32.3%. From this percentage, it can be seen that the most dominant type of language disorders experienced by autistic savant in Rain Man film is expressive language disorder. It means the autistic savant as an adult person also has difficulty in expressing or producing language. Key words: language disorder, autistic savant, expressive language disorder, receptive language disorder

Proceedings #45: Effects of Active and Sham tDCS on Lexical Decision in Three Persons with Aphasia

It is unclear how lesion location, task demands, and specific language deficits interact with ideal transcranial direct current stimulation (tDCS) montage placement to promote language recovery in persons with aphasia. The aim of this case report is to determine how three patients with different lesion locations and different aphasia types and severities respond during stimulation with the most common tDCS montage for aphasia during a lexical decision task. 3 persons with aphasia performed a lexical decision task during sham or active tDCS stimulation with anode over F7 and cathode over F8 (1 mA, 5x7 sponges, 20 minutes). The patient with the most anterior lesion and anomic aphasia was faster (p = 0.001) and more accurate in the discrimination of real words (p = 0.014) during the active condition, while the patient with the most posterior lesion and fluent aphasia was slower and less accurate (p = 0.013) during the active condition. These results show that it is likely that task sensitivities and individual aphasia/lesion profiles should be considered before determining a stimulation montage and that further research is necessary into the relationship between lesion location and montage efficacy.

Repetitive verbal behaviors are not always harmful signs: Compensatory plasticity within the language network in aphasia

Repetitive verbal behaviors such as conduite d’approche (CdA) and mitigated echolalia (ME) are well-known phenomena since early descriptions of aphasia. Nevertheless, there is no substantial fresh knowledge on their clinical features, neural correlates and treatment interventions. In the present study we take advantage of three index cases of chronic fluent aphasia showing CdA, ME or both symptoms to dissect their clinical and neural signatures. Using multimodal neuroimaging (structural magnetic resonance imaging and [18]-fluorodeoxyglucose positron emission tomography during resting state), we found that despite of the heterogeneous lesions in terms of etiology (stroke, traumatic brain injury), volume and location, CdA was present when the lesion affected in greater extent the left dorsal language pathway, while ME resulted from preferential damage to the left ventral stream. The coexistence of CdA and ME was associated with involvement of areas overlapping with the structural lesions and metabolic derangements described in the subjects who showed one of these symptoms (CdA or ME). These findings suggest that CdA and ME represent the clinical expression of plastic changes that occur within the spared language network and its interconnected areas in order to compensate for the linguistic functions that previously relied on the activity of the damaged pathway. We discuss the results in the light of this idea and consider alternative undamaged neural networks that may support CdA and ME.

Treatment of a pregnant woman with glioblastoma complicated by acute occlusive hydrocephalus in the subcompensation stage (from practice)

The study objective is to present a rare clinical observation, describe a successful 2-stage neurosurgical treatment of a pregnant patient with glioblastoma complicated by acute occlusive hydrocephalus.Materials and methods. A pregnant woman, 36 years (pregnancy 28–29 weeks), was urgently hospitalized with a suspicion for preeclampsia at a multispecialty hospital with a maternity ward. One day prior to hospitalization the patient developed hypertensive syndrome manifesting through headache, nausea, vomiting, depressed consciousness to stupor, then seizures in the extremities with loss of consciousness.Examination had shown malignant paraventricular tumor of the left temporal and parietal lobes accompanied by perifocal edema, brain dislocation, and acute occlusive triventricular hydrocephalus.Results. Treatment included the following stages: 1) emergency endoscopic third ventriculocisternostomy under local anesthesia, 2) premature delivery per cesarean section, 3) microsurgical resection of the brain tumor. Histological examination diagnosed glioblastoma (grade IV). The patient was discharged with minimal neurological deficiency (elements of motor and sensory aphasia) for administration of chemoradiation therapy.Conclusion. Surgical treatment of a patient with glioblastoma and acute occlusive hydrocephalus in the 3rd trimester can be performed safely and effectively for the mother and fetus in 2 stages. Third ventriculocisternostomy under local anesthesia is recommended as a method of cerebrospinal fluid drainage.

Cognitive profiles of fluent and non-fluent aphasia with the Russian version of Oxford Cognitive Screen

Event Abstract Back to Event Cognitive profiles of fluent and non-fluent aphasia with the Russian version of Oxford Cognitive Screen Maria Shendyapina1* and Brendan S. Weekes1 1 The University of Hong Kong, Hong Kong, SAR China Post-stroke aphasia reflects cognitive deficits to memory or executive functions (Kuzmina & Weekes, 2017) as well as language impairments. It was also known that stroke cognitive profiles reflect the integrity of language functions and can serve as a criteria for the prognosis of rehabilitation (Yeung & Law, 2010). Following results of Kuzmina and Weekes (2107), we compared cognitive deficits in patients who have fluent and non-fluent aphasia. In this present study we used the Russian version of the Oxford Cognitive Screen (Rus-OCS; see Shendyapina et al., 2019) which is more potent (shorter) than the Birmingham Cognitive Screen used by Kuzmina and Weekes (2017). Procedure. 25 individuals with fluent aphasia (58.65±16.26 years old, 10 females) and 23 patients with non-fluent aphasia (62.84±13.69 years old, 7 females) were assessed with the Rus-OCS and Russian version of the Montreal Cognitive Assessment (Rus-MoCA). Scores on subtests of attention, memory, praxis, language and number processing domains were recorded. The Kruskal-Wallis test was applied to examine differences between performance of both groups. Results. Both groups had significant impairments in verbal functions, although they differed in subtests of reading, verbal recall, verbal recognition and episodic memory wherein patients with nonfluent aphasia were significantly more impaired in the subtest performance (p < 0.05). Conclusions. Using the newly validated Rus-OCS, we identified an impairment to episodic memory and verbal functions in Russian speakers with non-fluent aphasia. These findings add to previous reports of the dissociations in cognitive impairment following brain damage for fluent and nonfluent patients with aphasia and in particular show the relevance of (brief) cognitive testing in the assessment of language impairments post-stroke. Theoretical implications will be discussed. References Kuzmina, E., & Weekes, B. S. (2017). Role of cognitive control in language deficits in different types of aphasia. Aphasiology, 31(7), 765-792. Shendyapina, M., Kuzmina, E., Kazymaev, S., Petrova, A., Demeyere, N., & Weekes, B. S. (2019). The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors. Neuropsychology, 33(1), 77. Yeung, O., & Law, S.-P. (2010). Executive functions and aphasia treatment outcomes: Data from ortho-phonological cueing therapy for anomia in Chinese. International Journal of Speech-Language Pathology, 12, 529–544. Keywords: cognitive assessment, fluent aphasia, non-fluent aphasia, Oxford Cognitive Screen, cognitive profile, episodic memory Conference: Academy of Aphasia 57th Annual Meeting, Macau, Macao, SAR China, 27 Oct - 29 Oct, 2019. Presentation Type: Poster presentation Topic: Eligible for student award Citation: Shendyapina M and Weekes BS (2019). Cognitive profiles of fluent and non-fluent aphasia with the Russian version of Oxford Cognitive Screen. Front. Hum. Neurosci. Conference Abstract: Academy of Aphasia 57th Annual Meeting. doi: 10.3389/conf.fnhum.2019.01.00038 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 29 Apr 2019; Published Online: 09 Oct 2019. * Correspondence: Ms. Maria Shendyapina, The University of Hong Kong, Pokfulam, Hong Kong, SAR China, mshend@hku.hk Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Maria Shendyapina Brendan S Weekes Google Maria Shendyapina Brendan S Weekes Google Scholar Maria Shendyapina Brendan S Weekes PubMed Maria Shendyapina Brendan S Weekes Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Imaging of semantic association judgements reveals areas of functional disruption and compensation remote from lesion in chronic Wernicke's aphasia

Imaging of semantic association judgements reveals areas of functional disruption and compensation remote from lesion in chronic Wernicke's aphasia

Quantifying the Differentiated Trajectory of the Wernicke’s-like Presentation of Logopenic Variant Primary Progressive Aphasia (lvPPA)

Quantifying the Differentiated Trajectory of the Wernicke’s-like Presentation of Logopenic Variant Primary Progressive Aphasia (lvPPA)