• In this study, AISI 2205 duplex stainless steel materials and P355GH pressure vessel steels are joined by using the same additional metal and powder, with the same parameters and submerged arc welding method. • Welded with SAW method, these materials were tested by eye, magnetic particle and radiographic examination methods to detect surface and sub-surface defects. No pores, voids or cracks were found in the materials after the magnetic particle test and radiographic test. In addition, solid spot and fixation of the welded samples worked, and welded samples showed no unacceptable angular distortion and high-low defect error. • Tensile, bending, impact notch and hardness tests were applied to determine the mechanical properties of welded samples. When the tensile test results are examined, it is seen that although the highest tensile strength of the main materials is in AISI2205 material, % elongation values are very close to each other. • Successful results have been achieved from all SAW of duplex stainless steel and pressure vessel steels. This result shows that additional metal, welding flux and welding parameters are suitable for joining duplex stainless steel and pressure vessel steels. In this study, duplex stainless (AISI2205) steel and pressure vessel (P355GH) steel have been joined by submerged arc welding method (SAW). Three different joining operations (AISI2205-AISI2205), (P355GH-P355GH) and (AISI2205-P355GH) were performed respectively. ELOX UP 309 L submerged arc welding wire and Eliflux Bss-A submerged arc welding powder were used for joining materials. Welded materials have been tested with eye, magnetic particle and radiographic examination methods were used to detect surface and subsurface defects. Tensile, bending, Charpy impact notch and hardness tests were then performed to determine the mechanical properties of welded samples. Additionally, microstructure investigations were made to determine the structural changes in the welding zone. Various NDE technqiues were adopted to investigate the quality of the welds. As a result of tensile tests, the rupture was made of welding metal in AISI2205-AISI2205 joints and P355GH in other joints was made of base material. No visible errors were observed in the welding area after bending test. When the V-notch impact energies of the materials were compared, the highest toughness value was measured in the ITAB of AISI2205 material and the lowest toughness value was measured in the P355GH weld metal. In hardness measurements, the highest hardness value was obtained in the HAZ of the AISI2205 material, whereas the lowest hardness was measured in the P355GH base material. Microstructure studies indicated that the weld metal comprised a dendritic structure, and the grains were observed to become coarse in the region adjacent to the melting boundary on the main material side.